When white blood cells, meant to protect the body from infection, are overly activated, they eject their DNA into nets, further disrupting the immune system and making patients more likely to develop a potentially severe reaction to immunotherapy.

Changing how often a popular cancer therapy is delivered would reduce greenhouse gas emissions and improve environmental impact without decreasing cancer survival, according to a new analysis from researchers at the University of Michigan Health Rogel Cancer Center.

Researchers uncovered nine elements that have significant effects on a whether a patient may develop pneumonia, with nearly 20% of patients moving into a higher risk category based on what occurred during or following the surgery.

A melanoma survivor shares facts and tips about preventing all types of skin cancer.

The availability of clinical trials of new treatments for cancer varies greatly by geography, and a new study shows more socially vulnerable areas have far fewer.

On today’s The Fundamentals is Dr. Brummett, Professor at the University of Michigan where he serves as the Senior Associate Chair for Research in the Department of Anesthesiology. He has more than 280 publications, including articles in top journals such as JAMA, JAMA Surgery, Anesthesiology, and Annals of Surgery. He is the Co-Director of the Opioid Prescribing Engagement Network or OPEN at the University of Michigan, which aims to apply a preventative approach to the opioid epidemic in the US through appropriate prescribing after surgery, dentistry and emergency medicine. Moreover, he is the Co-Director of the cross-campus Opioid Research Institute, which was launched in the spring of 2023. He leads multiple NIH grants studying these concepts and receives funding from the Michigan Department of Health and Human Services, SAMHSA, CDC, and multiple foundations. You can learn more about Dr. Brummett here, and you can follow Dr. Brummett @drchadb and the department of anesthesiology @UMichAnesthesia on X.

Today on The Fundamentals is Dr. Maria Castro, the R.C. Schneider collegiate professor of neurosurgery, and a professor of cell and developmental biology at the University of Michigan Medical School. Her research program aims to develop immunotherapies for primary and metastatic brain cancer, studying basic immune biology mechanisms leading to clinical implementation. She has been inducted into the American Association for the Advancement of Sciences, the Latin American Academy of Sciences, and the American Institute for Medical and Biological Engineering College of Fellows. She has won numerous awards for her contributions to basic science and cancer research and is a diversity ambassador for the Cancer Biology Graduate Training Program. You can learn more about Dr. Castro here, and you can follow her @castro2355_mg, the Rogel Cancer Center @UMRogelCancer, the department of neurosurgery @umichneuro, Michigan Neurscience Institute @UM_MNI and the department of cell and developmental biology @UMCDB on X

A study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas.

Experts in brain cancer outline current discoveries and offer a path of hope for glioblastoma treatment

The Clinical Trials Support Office (CTSO) is pleased to announce that Mio Nakamura, MD, MS, Clinical Assistant Professor, Dermatology, has been appointed as the new Associate Medical Director of the Michigan Clinical Trials Support Unit (M-CTSU) and Michigan Clinical Research Unit (MCRU). Dr. Nakamura’s appointment will begin July 1, 2024, and is a 2-year term.

A new urine-based test addresses a major problem in prostate cancer: how to separate the slow growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.

In the past two years, 60% of people age 50 to 80 have visited an urgent care clinic, or a clinic based in a retail store, workplace or vehicle, according to new findings from the University of Michigan National Poll on Healthy Aging.

A Michigan Medicine study finds that storing chemicals in a garage at home may associate with an increased risk of ALS.

Telehealth study of patient portal e-visits by Medicare participants shows few had an interaction for which their provider billed them.

At-home test can detect tumor DNA fragments in urine samples, providing a non-invasive alternative to traditional blood-based biomarker tests