When white blood cells, meant to protect the body from infection, are overly activated, they eject their DNA into nets, further disrupting the immune system and making patients more likely to develop a potentially severe reaction to immunotherapy.

Changing how often a popular cancer therapy is delivered would reduce greenhouse gas emissions and improve environmental impact without decreasing cancer survival, according to a new analysis from researchers at the University of Michigan Health Rogel Cancer Center.

Assistant Professor Rachel Niederer of the Department of Biological Chemistry at U-M Medical School is one of the recipients of a collaborative award from the Cystic Fibrosis Foundation.

Assistant Professor Chase Weidmann of the Department of Biological Chemistry at U-M Medical School is the 2024 recipient of the Outstanding Faculty Mentor Award from the CMB Program.

Researchers uncovered nine elements that have significant effects on a whether a patient may develop pneumonia, with nearly 20% of patients moving into a higher risk category based on what occurred during or following the surgery.

Yan Zhang, PhD, Jeanne Stuckey, PhD, Markus Ruetz, PhD, Michael Cianfrocco, PhD, and Wei Cheng, PhD, have been promoted.

The newest version of the heparin reversal drug, described in a recent issue of Advanced Healthcare Materials, adjusted the number of protons bound to it, making the molecule less positive so it would preferentially bind to the highly negative heparin, resulting in a much safer drug.

A team of researchers have spent the past eight years looking at better ways to transport organs for donation, specifically hearts, to improve the number of organs that can be used for transplants. They found that using a modified normothermic perfusion system heart preservation was feasible for up to 24 hours.

A melanoma survivor shares facts and tips about preventing all types of skin cancer.

Recent research achievements from the Giessen lab.

The availability of clinical trials of new treatments for cancer varies greatly by geography, and a new study shows more socially vulnerable areas have far fewer.

Today on The Fundamentals is Dr. Maria Castro, the R.C. Schneider collegiate professor of neurosurgery, and a professor of cell and developmental biology at the University of Michigan Medical School. Her research program aims to develop immunotherapies for primary and metastatic brain cancer, studying basic immune biology mechanisms leading to clinical implementation. She has been inducted into the American Association for the Advancement of Sciences, the Latin American Academy of Sciences, and the American Institute for Medical and Biological Engineering College of Fellows. She has won numerous awards for her contributions to basic science and cancer research and is a diversity ambassador for the Cancer Biology Graduate Training Program. You can learn more about Dr. Castro here, and you can follow her @castro2355_mg, the Rogel Cancer Center @UMRogelCancer, the department of neurosurgery @umichneuro, Michigan Neurscience Institute @UM_MNI and the department of cell and developmental biology @UMCDB on X

A study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas.

Experts in brain cancer outline current discoveries and offer a path of hope for glioblastoma treatment