When white blood cells, meant to protect the body from infection, are overly activated, they eject their DNA into nets, further disrupting the immune system and making patients more likely to develop a potentially severe reaction to immunotherapy.

Changing how often a popular cancer therapy is delivered would reduce greenhouse gas emissions and improve environmental impact without decreasing cancer survival, according to a new analysis from researchers at the University of Michigan Health Rogel Cancer Center.

Youth with heart disease enrolled in unique program that teaches resilience and builds connections with their peers

M&I Teresa O'Meara is a recipient of of the Investigators in the Pathogenesis of Infectious Disease (PATH) program of the Burroughs Wellcome Fund. Her lab will further study the mechanisms of attachment and virulence for C. auris, with a focus on how the novel adhesin contributes to pathogenesis. On a practical level, their work will suggest strategies for developing vaccine candidates and therapeutics to limit disease caused by this emerging pathogen.

On May 16, 2024, the Regents of the University of Michigan promoted Melanie Pearson, Ph.D., to Associate Professor on the Research Track, effective September 1, 2024.

Faith Anderson, Jaime Fuentes, and Andrés Rivera Ruiz, M&I Ph.D. candidates, have been awarded prestigious fellowships from Rackham Graduate School, in recognition of their academic excellence. Congratulations, we’re so proud of you!

A melanoma survivor shares facts and tips about preventing all types of skin cancer.

In emergency rooms and intensive care units across the country, clinicians make split-second decisions about which antibiotics to give a patient when a life threatening infection is suspected. Now, a study reveals that these decisions may have unintended consequences for patient outcomes.

Recent developments represent a dramatic change from long standing federal policy around these substances that has historically criminalized their use and blocked or delayed research efforts into their therapeutic potential.

The availability of clinical trials of new treatments for cancer varies greatly by geography, and a new study shows more socially vulnerable areas have far fewer.

A study builds on previous work that found depriving T cells of iron prevented cells from proliferating. The current study, published in PNAS, found that excess iron is just as problematic.

Today on The Fundamentals is Dr. Maria Castro, the R.C. Schneider collegiate professor of neurosurgery, and a professor of cell and developmental biology at the University of Michigan Medical School. Her research program aims to develop immunotherapies for primary and metastatic brain cancer, studying basic immune biology mechanisms leading to clinical implementation. She has been inducted into the American Association for the Advancement of Sciences, the Latin American Academy of Sciences, and the American Institute for Medical and Biological Engineering College of Fellows. She has won numerous awards for her contributions to basic science and cancer research and is a diversity ambassador for the Cancer Biology Graduate Training Program. You can learn more about Dr. Castro here, and you can follow her @castro2355_mg, the Rogel Cancer Center @UMRogelCancer, the department of neurosurgery @umichneuro, Michigan Neurscience Institute @UM_MNI and the department of cell and developmental biology @UMCDB on X

Four Graduate Program in Immunology alumni participated in a panel discussion about their career paths.

A study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas.

This M&I award recognizes outstanding dissertations.