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The Fundamentals
Treating Diabetes & Weight: The Ozempic & Wegovy Effect
Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss. You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.
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Health Lab
Path forward for glioblastoma treatment
Experts in brain cancer outline current discoveries and offer a path of hope for glioblastoma treatment
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Health Lab
Researchers discover urine based test to detect head and neck cancer
At-home test can detect tumor DNA fragments in urine samples, providing a non-invasive alternative to traditional blood-based biomarker tests
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Health Lab
Discovery reveals how this common stinky gas is processed to promote blood vessel growth
A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.
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Health Lab
Is lung cancer treatment working? This chip can tell from a blood draw
Using a chip to process blood samples, doctors can monitor the amount of cancer cells in a patient’s blood to determine how well a treatment is working by the fourth week, according to a new study.
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Health Lab
Treating prostate cancer without major side effects
Recently approved by the Food and Drug Administration, Pluvicto is a radionuclide-labelled drug administered to patients showing promising results.
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Health Lab
Metabolite tells cells whether to repair DNA
Findings from researchers at the University of Michigan Health Rogel Cancer Center, published in Cancer Discovery, show how a specific nucleotide metabolite called GTP controls responses to radiation and chemotherapy in an unexpected way.
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Health Lab
Gene links exercise endurance, cold tolerance and cellular maintenance in flies
A study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in fruit flies.
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Health Lab
Genetic mutation linked to adrenal tumor and hypertension
Research from the Department of Molecular & Integrative Physiology at Michigan Medicine identifies a previously unknown genetic mutation that causes the disease called primary aldosteronism in certain populations.
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News Release
13 U-M graduate medical education programs ranked in the top 10 by Doximity
There are 13 U-M graduate medical education programs ranked in the top 10 by Doximity.
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Health Lab
Changing the way immune-based cancer drugs are delivered could reduce costs by 14%
An analysis finds that up to millions of dollars could be saved annually on cancer immunotherapy treatments across the Veterans Health Administration by reconsidering how those drugs are delivered.
surgeon looking in distant
Health Lab
In academic hospitals, study finds these groups disproportionately affected by workplace mistreatment
A study finds that women, racial and ethnic minorities, and individuals identifying as lesbian, gay, bisexual, transgender and queer are disproportionately affected by workplace mistreatment in academic medicine, and this mistreatment negatively impacts their mental health.
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Health Lab
A new regulator of innate immunity identified
One of the most important protein complexes in mammals involved in ERAD is called SEL1L-HRD1. Recent research finds that this protein complex helps regulate another critical protein involved in innate immunity, called STING, at the endoplasmic reticulum.
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Health Lab
Evidence of conscious-like activity in the dying brain
A Michigan Medicine study provides early evidence of a surge of activity correlated with consciousness in the dying brain.