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The Fundamentals
Treating Diabetes & Weight: The Ozempic & Wegovy Effect
Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss. You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.
Scientific illustration of gliobastoma cells in the brain
Health Lab
Path forward for glioblastoma treatment
Experts in brain cancer outline current discoveries and offer a path of hope for glioblastoma treatment
Illustration of a microscope
Health Lab
Helpful enzymes vanish in many patients with antiphospholipid syndrome
Researchers recently revealed a new mechanism behind antiphospholipid syndrome that the investigators hope will eventually allow treatments to be targeted closer to the source of the problem.
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Health Lab
Researchers discover urine based test to detect head and neck cancer
At-home test can detect tumor DNA fragments in urine samples, providing a non-invasive alternative to traditional blood-based biomarker tests
Close up image of red blood cells moving through veins
Health Lab
Discovery reveals how this common stinky gas is processed to promote blood vessel growth
A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.
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Health Lab
Everyone plays a role in improving cancer health equity
As guest editor for a themed journal issue, Lori Pierce helps highlight the multiple factors that can make cancer care and prevention more equitable and reduce the burden of this disease for all
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Health Lab
Sickle cell raises COVID risk, but vaccination lags
Vaccination against the coronavirus was much lower in adults and children with sickle cell disease despite a higher risk of severe COVID-19.
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Health Lab
Studying cells to improve medulloblastoma treatment
Research from Michigan Medicine experts is shedding light and potentially expanding options for patients living with an aggressive childhood cancer.
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Health Lab
Gene therapy to treat sickle cell disease
How two newly approved gene therapies, including novel technology CRISPR, may help kids and adults with inherited blood disorders
woman holding head down in library
Health Lab
Genetic “protection” against depression no match for pandemic stress
By studying first-year college students’ experiences and backgrounds, scientists may have discovered a way to go beyond genetics to predict which students might be more or less vulnerable to stress-related depression.
woman in hospital on left in ICU and the other right side woman standing in jean jacket and black clothes smiling
Health Lab
Brain tumor and car crash survivor aspires to be example for others living with disabilities
A car accident at age 20 left Sahar Mashhour in the intensive care unit for three months. Almost six years later, Mashhour is still pursuing her passions proving that her disability doesn’t limit her ability, but instead helps her see life through a different lens.
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Health Lab
Medication found safe and effective for preventing bleeding in infants with hemophilia A
Infants with hemophilia A who received monoclonal antibody emicizumab experienced few bleeding events and no serious complications, a study suggests.
cannabis leaf sketched blue
Health Lab
1 in 8 older adults use cannabis products, suggesting need to screen for risks
The Michigan Medicine finding suggest a need for more education and screening of older adults for cannabis-related risks.
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Health Lab
Gene links exercise endurance, cold tolerance and cellular maintenance in flies
A study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in fruit flies.
man looking at guns clerk store
Health Lab
High rate of mental health problems and political extremism found in those who bought firearms during COVID pandemic
Firearm purchases rose during the pandemic and a survey shows high rates of mental health issues and political extremism among those who bought guns during 2020 and 2021.