Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss. You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.

A JAMA viewpoint outlines the tragic story of Shandra Eisenga, a patient who received spine surgery for back pain only to inexplicably contract tuberculosis.

A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.

Sudden cardiac arrest in young athletes: 5 things parents should know

Through a $4.17M NIH grant, a team of biomedical engineers, medical clinicians and data scientists from the Max Harry Weil Institute for Critical Care Research and Innovation is collaboratively researching ways to develop a portable, non-invasive breathalyzer-type device and corresponding algorithm to quickly and accurately diagnose acute respiratory distress syndrome (ARDS).

Researchers at Michigan Medicine developed an AI-driven algorithm that accurately predicts death and complications after PCI — which could emerge as a tool for clinicians as they determine treatment for blocked heart arteries.

Kyle and Kaylee Berner are enjoying making memories with their baby, Bennett, outside hospital walls. Courtesy of the Berners

Patients who experience this condition following the Fontan continue to have a high risk of death from the time they’re waitlisted for a new heart through receiving the transplant, according to a 20-center study led by Michigan Medicine. And one specific complication called cyanosis – or experiencing less than normal oxygen blood levels – was associated with worsened survival.

The vast majority of people who have a minimally invasive heart valve replacement procedure do not participate in recommended cardiac rehabilitation, a Michigan Medicine-led study finds.

For the first time in more than 20 years, dozens of pediatric cardiologists, surgeons and other health professionals have come together to develop new guidelines intended to improve heart surgery care for this population of children and teens.

A study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in fruit flies.

Research from the Department of Molecular & Integrative Physiology at Michigan Medicine identifies a previously unknown genetic mutation that causes the disease called primary aldosteronism in certain populations.

The Mobile Monitoring Transformation Project, supported by the Sickbay Clinical Platform will allow care team members to access data from cardiac monitors and all connected bedside devices on workstations, PCs, phones and tablets. The new web-based technology will transform bedside care and greatly enhance collaboration among care team members. A pilot was run last year, and units in different buildings will begin using the new technology this week, with a larger rollout planned.

One of the most important protein complexes in mammals involved in ERAD is called SEL1L-HRD1. Recent research finds that this protein complex helps regulate another critical protein involved in innate immunity, called STING, at the endoplasmic reticulum.