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The Fundamentals
Treating Diabetes & Weight: The Ozempic & Wegovy Effect
Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss. You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.
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Health Lab
It’s easier now to treat opioid addiction with medication -- but use has changed little
Buprenorphine prescribing for opioid addiction used to require a special waiver from the federal government, but a new study shows what happened in the first year after that requirement was lifted.
Pill capsule pushing through a paper with amoxicillin printed on it.
Health Lab
Rise seen in use of antibiotics for conditions they can’t treat – including COVID-19
Overuse of antibiotics can lead bacteria to evolve antimicrobial resistance, but Americans are still receiving the drugs for many conditions that they can’t treat.
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Medical School News
Four Medical School faculty recognized by American Association for the Advancement of Science
Four with Medical School ties are among 12 University of Michigan faculty and staff members recognized by the American Association for the Advancement of Science (AAAS) as 2023 fellows in recognition of their extraordinary achievements.
Illustration of hand holding list, with pill bottle in opposite and and small pic of doctor talking to patient
Health Lab
New urine-based test detects high grade prostate cancer, helping men avoid unnecessary biopsies
A new urine-based test addresses a major problem in prostate cancer: how to separate the slow growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.
Close up image of red blood cells moving through veins
Health Lab
Discovery reveals how this common stinky gas is processed to promote blood vessel growth
A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.
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Health Lab
Parents’ top resolutions: More patience, less time on phones
6 ways families can make resolutions stick
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Health Lab
Dental opioid prescriptions still declining, but not as quickly as pre-pandemic
Dental pain treatment with opioid painkillers like Oxycontin and Oxycodone declined before and during the pandemic but the rate of decline slowed after 2020.
Health Lab
Hungry for more
Metabolism pathways make tumors sensitive or resistant to treatments. A collaborative group leverages these avenues to explore the growing foundation of new potential therapies
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Health Lab
Gene links exercise endurance, cold tolerance and cellular maintenance in flies
A study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in fruit flies.
stethoscope
Health Lab
Genetic mutation linked to adrenal tumor and hypertension
Research from the Department of Molecular & Integrative Physiology at Michigan Medicine identifies a previously unknown genetic mutation that causes the disease called primary aldosteronism in certain populations.
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Health Lab
Prostate cancer drug shows promise against COVID
Michigan Medicine researchers looked into a drug in development to treat prostate cancer called proxalutamide, which works by blocking an enzyme called TMPRSS2 (transmembrane protease, serine 2) that is regulated by androgen receptors, as a potential therapeutic for COVID.
gloved hand doing microplate samples
Health Lab
Study brings insight to kidney cancer with gene mutation
A study from clinicians and researchers at the University of Michigan Rogel Cancer Center reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.
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News Release
13 U-M graduate medical education programs ranked in the top 10 by Doximity
There are 13 U-M graduate medical education programs ranked in the top 10 by Doximity.
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The Fundamentals
Good collaborators are why I stayed
An interview with Dr. Steven Kunkel on research at U-M Medical School.