The majority of older adults with cognitive impairment are still driving, despite concerns raised by caregivers and others, a Michigan Medicine study in a South Texas community finds.

The Mobile Monitoring Transformation Project, supported by the Sickbay Clinical Platform will allow care team members to access data from cardiac monitors and all connected bedside devices on workstations, PCs, phones and tablets. The new web-based technology will transform bedside care and greatly enhance collaboration among care team members. A pilot was run last year, and units in different buildings will begin using the new technology this week, with a larger rollout planned.

A new Publication by Carpenter, ElHossiny and Kadiyala (Pasca di Magliano Lab) was published in Cancer Discovery.

"Approaches to vascularizing human brain organoids," was published in PLOS BIOLOGY.

Michigan Medicine research finds that some patients with PE, a blood clot in one or more pulmonary arteries, may be hospitalized unnecessarily due to computed tomography, or CT, imaging results rather than clinical risk factors.

"Ptbp1 deletion does not induce astrocyte-to-neuron conversion," was published in Nature.

"Senescence-induced immune remodeling facilitates metastatic adrenal cancer in a sex-dimorphic manner," was published in Nature Aging.

"Recruitment of the SNX17-Retriever recycling pathway regulates synaptic function and plasticity," was published in the Journal of Cell Biology.

A highly complicated experiment designed to reveal how SARS-CoV-2 causes infection by hijacking cellular machinery is published by a team of investigators at Michigan Medicine.

"Mechanistic Analysis of CCP1 in Generating ΔC2 α-Tubulin in Mammalian Cells and Photoreceptor Neurons," was published in Biomolecules.

"LabGym: Quantification of user-defined animal behaviors using learning-based holistic assessment," was published in Cell Reports Methods.

"Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication," has been published in the Journal of Cell Biology.

"DSCAM gene triplication causes excessive GABAergic synapses in the neocortex in Down syndrome mouse models," was published in PLOS BIOLOGY.

Michigan Medicine study shows model that predicts patient deterioration defies traditional challenges.

"Derepression of Y-linked multicopy protamine-like genes interferes with sperm nuclear compaction in D. melanogaster," has been published in Proceedings of the National Academy of Sciences (PNAS).