Early treatment of pediatric Crohn’s disease with anti-tumor necrosis factor medications can substantially reduce the risk of perianal fistulas in Crohn’s disease. Michigan Medicine researchers confirmed this finding using prospective data. 

A study from University of Michigan researchers may explain why some patients with Crohn’s disease continue to experience symptoms, even in the absence of inflammation.

In a report in JAMA Surgery, researchers propose two novel tools that leverage the All of Us dataset to look at acute health events such as surgery.

For people taking the popular blood thinners rivaroxaban (brand name Xarelto) and apixaban (brand name Eliquis), after having a blood clot, a reduced dose may limit the future risk of bleeding as well as hospital visits, a Michigan Medicine-led study suggests.

Hearing loss is one of the most common conditions of aging, affecting nearly two-thirds of older adults over the age of 70, but it’s not just a matter of diminished hearing. Hearing loss can contribute to poor psychosocial outcomes for patients including loneliness, depression, and social isolation. New research also shows that hearing loss is linked to a higher risk of cognitive decline and dementia. In fact, the 2024 Lancet Commission on Dementia Prevention, Intervention, and Care identified hearing loss as one of 14 modifiable risk factors for dementia. According to the commission, treating hearing loss could prevent up to 7% of dementia cases globally, making it one of the most impactful areas for potential prevention. This raises the question of whether use of hearing aids in people with hearing loss can reduce or mitigate this increased dementia risk. To help us understand these connections and the latest research in this area, we are joined today by Dr. Alison Huang, an epidemiologist and Senior Research Associate from the Johns Hopkins Cochlear Center for Hearing and Public Health. Her research studies the impact of sensory loss on cognitive and mental health in older adults. Dr. Huang was an author of the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) study, a large, multicenter randomized controlled trial that tested whether treating hearing loss in older adults could help slow cognitive decline published in the Lancet. Alison Huang, PhD, MPH Link to article: Lin FR, Pike JR, Albert MS, Arnold M, Burgard S, Chisolm T, Couper D, Deal JA, Goman AM, Glynn NW, Gmelin T, Gravens-Mueller L, Hayden KM, Huang AR, Knopman D, Mitchell CM, Mosley T, Pankow JS, Reed NS, Sanchez V, Schrack JA, Windham BG, Coresh J; ACHIEVE Collaborative Research Group. Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial. Lancet. 2023 Sep 2;402(10404):786-797. doi: 10.1016/S0140-6736(23)01406-X. Epub 2023 Jul 18. PMID: 37478886; PMCID: PMC10529382.

The second episode of Well-Being at Michigan Medicine with Dr. Elizabeth Harry welcomes Dr. Louito Edje as guest. Dr. Edje is the senior associate dean for medical education at the U-M Medical School. In the conversation, Dr. Edje speaks to the importance of well-being in the education space. From policy positions to leadership development, Dr. Edje and Dr. Harry touch on ways that Michigan Medicine is empowering and aiding its current generation of learners who are set to be the next generation of faculty with positive well-being messaging and tools. The two also speak to how psychological safety and speaking up in important matters bring people together to provide better outcomes for patients. Learn more about the host of Well-Being at Michigan Medicine, Dr. Elizabeth Harry. Episode guest: Louito Edje, M.D., MHPE, FAAFP