Zirui Huang, PhD
Research Assistant Professor of Anesthesiology and Co-Director
Center for Consciousness Science
[email protected]

Available to mentor

Zirui Huang, PhD
Research Assistant Professor
  • About
  • Qualifications
  • Research Overview
  • Recent Publications
  • About

    I am a Research Assistant Professor in the Department of Anesthesiology and a member of the Center for Consciousness Science at the University of Michigan Medical School. I have a multidisciplinary background including psychology, biology, cognitive neuroscience, and neuroimaging. I study the mechanistic role of large-scale brain networks in conscious cognition and its alteration by pharmacologic, neuropathologic and psychiatric manipulations using functional magnetic resonance imaging (fMRI).

    Qualifications
    • Postdoctoral Fellow
      University of Michigan Medical School, Department of Anesthesiology, 2018
    • Postdoctoral Fellow
      University of Ottawa, Institute of Mental Health Research, 2016
    • PhD in Cognitive Neuroscience
      Institute of Psychology, Chinese Academy of Sciences, Beijing, 2012
    • BS in Biotechnology
      Department of Biology, China Agriculture University, Beijing, 2007
    Research Overview

    The neural substrates of consciousness, e.g., the boundaries between conscious and non-conscious processing.
    Neural signatures in human subjects during awake, anesthesia, vegetative state, and mental/cognitive disorders.
    Spatiotemporal configurations and alterations of large-scale brain dynamics.
    Perceptual awareness.

    Recent Publications See All Publications
    • Journal Article
      Measuring the dynamic balance of integration and segregation underlying consciousness, anesthesia, and sleep in humans.
      Jang H, Mashour GA, Hudetz AG, Huang Z. Nat Commun, 2024 Oct 24; 15 (1): 9164 DOI:10.1038/s41467-024-53299-x
      PMID: 39448600
    • Journal Article
      Propofol disrupts the functional core-matrix architecture of the thalamus in humans.
      Huang Z, Mashour GA, Hudetz AG. Nat Commun, 2024 Sep 9; 15 (1): 7496 DOI:10.1038/s41467-024-51837-1
      PMID: 39251579
    • Additional Scholarship
      The brain in balance: Researchers develop a new measure of consciousness
      Malcom K. 2024 Nov 1;
    • Preprint
      Neural Correlates of Psychedelic, Sleep, and Sedated States Support Global Theories of Consciousness.
      Dai R, Jang H, Hudetz AG, Huang Z, Mashour GA. 2024 Oct 23; DOI:10.1101/2024.10.23.619731
      PMID: 39484478
    • Preprint
      Thalamic Roles in Conscious Perception Revealed by Low-Intensity Focused Ultrasound Neuromodulation.
      Jang H, Fotiadis P, Mashour GA, Hudetz AG, Huang Z. 2024 Oct 10; DOI:10.1101/2024.10.07.617034
      PMID: 39416133
    • Presentation
      Mapping the Thalamocortical Dialogue: From Anesthesia to Conscious Perception (Zoom)
      2024 Oct 1;
    • Journal Article
      Theoretical Neurobiology of Consciousness Applied to Human Cerebral Organoids.
      Owen M, Huang Z, Duclos C, Lavazza A, Grasso M, Hudetz AG. Camb Q Healthc Ethics, 2023 Oct 18; 1 - 21. DOI:10.1017/S0963180123000543
      PMID: 37850471
    • Additional Scholarship
      How the brain's inner chamber governs your state of consciousness
      Malcom K. 2024 Sep 9;
    Featured News & Stories brain drawn
    Health Lab
    The brain in balance
    In a recent study, using network neuroscience, investigators found a way to objectively determine the balance of integration and segregation in fMRI-measured brain signals during wakefulness as well as during sleep and anesthesia.
    navy background with wavy thicker lines going through and blue brain that turns red and then fades and white dots in middle that half turn red
    Health Lab
    How the brain's inner chamber governs your state of consciousness
    Investigators at Michigan Medicine, who are studying the nature of consciousness, have successfully used the drug to identify the intricate brain geometry behind the unconscious state, offering an unprecedented look at brain structures that have traditionally been difficult to study.