Steven E Harte
Associate Professor of Anesthesiology
Associate Professor of Internal Medicine and Program Associate
Chronic Pain and Fatigue Research Center
[email protected]

Available to mentor

Steven E Harte
Associate Professor
  • About
  • Links
  • Qualifications
  • Research Overview
  • Recent Publications
  • About

    Dr. Harte is a psychobiologist and an Associate Professor of Anesthesiology and Internal Medicine with 25 years of experience studying and teaching pain science. His NIH-funded research program leverages preclinical models, psychophysics, inflammatory biomarkers, patient-reported outcomes measures, wearables, and functional brain imaging to investigate mechanisms of chronic pain and analgesic treatments. Specific areas of interest include multisensory neural integration, cannabinoids, environmental influences on pain, pain affect, mechanisms of pain modulation, and analgesic drug development. He is a member of several national pain research collaborations, including the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network, the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN), the HEAL BACPAC and BEST initiatives, and the recently completed AURORA Study on trauma where he leads the development and implementation of multi-site quantitative sensory testing (QST). Dr. Harte is a faculty affiliate of the U-M Neuroscience Graduate Program, Michigan Neuroscience Institute, and Sensory Science Initiative. He is Director of the Postdoctoral T32 in Translational Science at the Michigan Institute for Clinical and Health Research (MICHR) and Co-Director/Co-PI of the HEAL National K12 Clinical Pain Career Development Program. Lastly, he is engaged in the development of novel medical and research devices and e-Health delivery applications, and is Co-Founder/Chief Scientific Officer of Arbor Medical Innovations, LLC. Dr. Harte holds several patents for pain measurement and wearable technology resulting from this work.

    Links
    • HEAL K12
    Qualifications
    • Postdoctoral Research Fellow
      University of Michigan Medical School, Internal Medicine
    • Postdoctoral Translational Science Scholar
      University of Michigan Medical School, Ann Arbor
    • PHD
      Wayne State University, Detroit, 2005
    • MA
      Wayne State University, Detroit, 2002
    Research Overview

    • Quantitative sensory testing and multisensory processing
    • Preclinical pain assessment
    • Pain neuroimaging
    • Neuropsychopharmacology
    • Neural-Immune interactions
    • Consciousness neuroscience
    • Environmental and architectural influences on pain and behavior
    • Biomedical technology development

    Recent Publications See All Publications
    • Journal Article
      Elevated posterior insula glutamate in patients with sickle cell disease.
      Zhou X, Ichesco E, Pucka AQ, Liu Z, O'Brien AR, Harte SE, Harris RE, Wang Y. J Pain, 2024 Nov 28; 27: 104743 DOI:10.1016/j.jpain.2024.104743
      PMID: 39615812
    • Preprint
      Peritraumatic C-reactive protein levels predict pain outcomes following traumatic stress exposure in a sex-dependent manner.
      McKibben LA, Layne MN, Albertorio-Sáez LM, Zhao Y, Branham EM, House SL, Beaudoin FL, An X, Stevens JS, Neylan TC, Clifford GD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O'Neil BJ, Sanchez LD, Bruce SE, Sheridan JF, Harte SE, Kessler RC, Koenen KC, Ressler KJ, McLean SA, Linnstaedt SD. 2024 Dec 7; DOI:10.1101/2024.12.03.24318221
      PMID: 39677432
    • Journal Article
      Brain network hypersensitivity underlies pain crises in sickle cell disease.
      Joo P, Kim M, Kish B, Nair VV, Tong Y, Liu Z, O'Brien ARW, Harte SE, Harris RE, Lee U, Wang Y. Sci Rep, 2024 Mar 27; 14 (1): 7315 DOI:10.1038/s41598-024-57473-5
      PMID: 38538687
    • Journal Article
      Heart rate variability wrist-wearable biomarkers identify adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure.
      Guichard L, An X, Neylan TC, Clifford GD, Li Q, Ji Y, Macchio L, Baker J, Beaudoin FL, Jovanovic T, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Gentile NT, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Bruce SE, Sheridan JF, Harte SE, Ressler KJ, Koenen KC, Kessler RC, McLean SA, AURORA Study Group . Psychiatry Res, 2024 Dec; 342: 116260 DOI:10.1016/j.psychres.2024.116260
      PMID: 39549594
    • Journal Article
      Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma.
      Webb EK, Stevens JS, Ely TD, Lebois LAM, van Rooij SJH, Bruce SE, House SL, Beaudoin FL, An X, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Murty VP, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Joormann J, Pizzagalli DA, Harte SE, Kessler RC, Koenen KC, Ressler KJ, McLean SA, Harnett NG. JAMA Psychiatry, 2024 Nov 1; 81 (11): 1090 - 1100. DOI:10.1001/jamapsychiatry.2024.2148
      PMID: 39083325
    • Journal Article
      Acupuncture Ameliorates Heightened Inflammatory/Immune Responses Accompanied with Improvement in Clinical Outcomes in Patients with Sickle Cell Disease
      Li W, Pucka A, Debats C, Reyes B, O'Brien ARW, Harte SE, Harris RE, Yu Q, Wang Y. Blood, 2024 Nov 5; 144 (Supplement 1): 2519 - 2519. DOI:10.1182/blood-2024-198474
    • Journal Article
      Altered Cerebral Functional Connectivity in Patients with Sickle Cell Disease
      Sridhar A, Ichesco E, Pucka AQ, O'Brien AR, Harte SE, Harris RE, Wang Y. Blood, 2024 Nov 5; 144 (Supplement 1): 3881 - 3881. DOI:10.1182/blood-2024-204453
    • Journal Article
      Self-Administered Acupressure Improves Pain and Quality of Life in Patients with Sickle Cell Disease
      Pucka AQ, Houran L, O'Brien AR, Harte SE, Harris RE, Pakbaz Z, Wang Y. Blood, 2024 Nov 5; 144 (Supplement 1): 2516 - 2516. DOI:10.1182/blood-2024-199218
    Featured News & Stories Nociplastic pain researchers Chelsea Kaplan, Steven Harte, Andrew Schrepf, Dan Clauw
    Department News
    What we know about nociplastic pain
    A new review article shines light on nociplastic pain, a type of pain some thought to be ‘all in your head’