Available to mentor
Dr. Harte is a psychobiologist and an Associate Professor of Anesthesiology and Internal Medicine with 25 years of experience studying and teaching pain science. His NIH-funded research program leverages preclinical models, psychophysics, inflammatory biomarkers, patient-reported outcomes measures, wearables, and functional brain imaging to investigate mechanisms of chronic pain and analgesic treatments. Specific areas of interest include multisensory neural integration, cannabinoids, environmental influences on pain, pain affect, mechanisms of pain modulation, and analgesic drug development. He is a member of several national pain research collaborations, including the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network, the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN), the HEAL BACPAC and BEST initiatives, and the recently completed AURORA Study on trauma where he leads the development and implementation of multi-site quantitative sensory testing (QST). Dr. Harte is a faculty affiliate of the U-M Neuroscience Graduate Program, Michigan Neuroscience Institute, and Sensory Science Initiative. He is Director of the Postdoctoral T32 in Translational Science at the Michigan Institute for Clinical and Health Research (MICHR) and Co-Director/Co-PI of the HEAL National K12 Clinical Pain Career Development Program. Lastly, he is engaged in the development of novel medical and research devices and e-Health delivery applications, and is Co-Founder/Chief Scientific Officer of Arbor Medical Innovations, LLC. Dr. Harte holds several patents for pain measurement and wearable technology resulting from this work.
HEAL K12
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Postdoctoral Research FellowUniversity of Michigan Medical School, Internal Medicine
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Postdoctoral Translational Science ScholarUniversity of Michigan Medical School, Ann Arbor
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PHDWayne State University, Detroit, 2005
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MAWayne State University, Detroit, 2002
• Quantitative sensory testing and multisensory processing
• Preclinical pain assessment
• Pain neuroimaging
• Neuropsychopharmacology
• Neural-Immune interactions
• Consciousness neuroscience
• Environmental and architectural influences on pain and behavior
• Biomedical technology development
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Zhou X, Ichesco E, Pucka AQ, Liu Z, O'Brien AR, Harte SE, Harris RE, Wang Y. J Pain, 2024 Nov 28; 27: 104743Journal ArticleElevated posterior insula glutamate in patients with sickle cell disease.
DOI:10.1016/j.jpain.2024.104743 PMID: 39615812 -
McKibben LA, Layne MN, Albertorio-Sáez LM, Zhao Y, Branham EM, House SL, Beaudoin FL, An X, Stevens JS, Neylan TC, Clifford GD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O'Neil BJ, Sanchez LD, Bruce SE, Sheridan JF, Harte SE, Kessler RC, Koenen KC, Ressler KJ, McLean SA, Linnstaedt SD. 2024 Dec 7;PreprintPeritraumatic C-reactive protein levels predict pain outcomes following traumatic stress exposure in a sex-dependent manner.
DOI:10.1101/2024.12.03.24318221 PMID: 39677432 -
Joo P, Kim M, Kish B, Nair VV, Tong Y, Liu Z, O'Brien ARW, Harte SE, Harris RE, Lee U, Wang Y. Sci Rep, 2024 Mar 27; 14 (1): 7315Journal ArticleBrain network hypersensitivity underlies pain crises in sickle cell disease.
DOI:10.1038/s41598-024-57473-5 PMID: 38538687 -
Guichard L, An X, Neylan TC, Clifford GD, Li Q, Ji Y, Macchio L, Baker J, Beaudoin FL, Jovanovic T, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Gentile NT, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Bruce SE, Sheridan JF, Harte SE, Ressler KJ, Koenen KC, Kessler RC, McLean SA, AURORA Study Group . Psychiatry Res, 2024 Dec; 342: 116260Journal ArticleHeart rate variability wrist-wearable biomarkers identify adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure.
DOI:10.1016/j.psychres.2024.116260 PMID: 39549594 -
Webb EK, Stevens JS, Ely TD, Lebois LAM, van Rooij SJH, Bruce SE, House SL, Beaudoin FL, An X, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Murty VP, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Joormann J, Pizzagalli DA, Harte SE, Kessler RC, Koenen KC, Ressler KJ, McLean SA, Harnett NG. JAMA Psychiatry, 2024 Nov 1; 81 (11): 1090 - 1100.Journal ArticleNeighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma.
DOI:10.1001/jamapsychiatry.2024.2148 PMID: 39083325 -
Li W, Pucka A, Debats C, Reyes B, O'Brien ARW, Harte SE, Harris RE, Yu Q, Wang Y. Blood, 2024 Nov 5; 144 (Supplement 1): 2519 - 2519.Journal ArticleAcupuncture Ameliorates Heightened Inflammatory/Immune Responses Accompanied with Improvement in Clinical Outcomes in Patients with Sickle Cell Disease
DOI:10.1182/blood-2024-198474 -
Sridhar A, Ichesco E, Pucka AQ, O'Brien AR, Harte SE, Harris RE, Wang Y. Blood, 2024 Nov 5; 144 (Supplement 1): 3881 - 3881.Journal ArticleAltered Cerebral Functional Connectivity in Patients with Sickle Cell Disease
DOI:10.1182/blood-2024-204453 -
Pucka AQ, Houran L, O'Brien AR, Harte SE, Harris RE, Pakbaz Z, Wang Y. Blood, 2024 Nov 5; 144 (Supplement 1): 2516 - 2516.Journal ArticleSelf-Administered Acupressure Improves Pain and Quality of Life in Patients with Sickle Cell Disease
DOI:10.1182/blood-2024-199218