Carol Elias
Molecular and Integrative Physiology
2800 Plymouth Rd, Building 25, 3682
Ann Arbor, Michigan 48109
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About
I earned my PhD in Neuroscience and Behavior from the University of São Paulo, Brazil, and completed my postdoctoral training in Neuroscience and Neuroendocrinology at Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA. After my postdoctoral training, I returned to Brazil to establish my research program at the Institute of Biomedical Sciences at the University of Sao Paulo, where I worked for approximately 10 years. In 2006, I returned to the United States for a 1-year sabbatical at the University of Texas Southwestern Medical Center in Dallas, TX and was invited to join the faculty at the Division of Hypothalamic Research. In 2013, I moved my laboratory to the University of Michigan in Ann Abor, MI. I currently hold the position of Professor in the Departments of Molecular & Integrative Physiology and of Obstetrics & Gynecology. I am the Director of the Neuroscience Graduate Program and the Director of the Michigan Mouse Metabolic Phenotyping Center (MMPC-Live), a National Center funded by the NIDDK. I am a member of the Latin American Academy of Sciences (ACAL) and a fellow of the American Academy for the Advancement of Sciences (AAAS).
Links
Laboratory website
Qualifications
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Leptin action in the brainHarvard Medical School, Beth Israel Deaconess Medical Center, Endocrinology, Boston, United States
1998 - 1999
Postdoctoral Fellowship
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Neural pathways in metabolic controlHarvard Medical School, Neurology, Boston, United States
1997 - 1998
Postdoctoral Fellowship
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PhDUniversity of Sao Paulo, Sao Paulo, SP, Brazil
1994 - 1997
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MSUniversity of Sao Paulo (USP), Sao Paulo, SP, Brazil
1991 - 1994
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BSUniversity of Campinas (UNICAMP), Campinas, SP, Brazil
1985 - 1990
Center Memberships
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Center MemberGlobal REACH
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Center MemberCenter for Cell Plasticity and Organ Design
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Center MemberCaswell Diabetes Institute
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Center MemberCenter for Global Health Equity
Research Overview
Research in our laboratory is focused on determining the mechanisms by which metabolic imbalance (e.g. obesity and diabetes) disrupts the reproductive neuroendocrine axis. We give special attention to the neural and molecular basis of the adipocyte-derived hormone leptin action in reproductive control. We are also interested in systems neuroscience and the interplay between neuroendocrine axes in development and metabolic dysfunction.
Recent Publications
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Anderson GM, Hill JW, Kaiser UB, Navarro VM, Ong KK, Perry JRB, Prevot V, Tena-Sempere M, Elias CF. Nature Reviews Endocrinology, 2024 Feb 1; 20 (2): 111 - 123.Journal ArticleMetabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra’s seminal work
DOI:10.1038/s41574-023-00919-z PMID: 38049643 -
Sáenz de Miera C, Feng J, Elias CF, Qi N. Journal of Visualized Experiments, 2024 Jan 9; 2023 (198):Journal ArticleRemote Neuronal Activation Coupled with Automated Blood Sampling to Induce and Measure Circulating Luteinizing Hormone in Mice
DOI:10.3791/65875 -
Beekly BG, Rupp A, Burgess CR, Elias CF. Frontiers in Neuroendocrinology, 2023 Jul 1; 70:Journal ArticleFast neurotransmitter identity of MCH neurons: Do contents depend on context?
DOI:10.1016/j.yfrne.2023.101069 PMID: 37149229 -
Cara AL, Burger LL, Beekly BG, Allen SJ, Henson EL, Auchus RJ, Myers MG, Moenter SM, Elias CF. Endocrinology United States, 2023 Mar 1; 164 (3):Journal ArticleDeletion of Androgen Receptor in LepRb Cells Improves Estrous Cycles in Prenatally Androgenized Mice
DOI:10.1210/endocr/bqad015 PMID: 36683455 -
Cisneros-Larios B, Elias CF. Frontiers in Neuroanatomy, 2023 Jan 6; 16:Journal ArticleSex differences in the coexpression of prokineticin receptor 2 and gonadal steroids receptors in mice
DOI:10.3389/fnana.2022.1057727 -
Dos Santos WO, Wasinski F, Tavares MR, Campos AMP, Elias CF, List EO, Kopchick JJ, Szawka RE, Donato J. Endocrinology United States, 2022 Aug 1; 163 (8):Journal ArticleAblation of Growth Hormone Receptor in GABAergic Neurons Leads to Increased Pulsatile Growth Hormone Secretion
DOI:10.1210/endocr/bqac103 PMID: 35803590 -
Chaves FM, Wasinski F, Tavares MR, Mansano NS, Frazao R, Gusmao DO, Quaresma PGF, Pedroso JAB, Elias CF, List EO, Kopchick JJ, Szawka RE, Donato J. Endocrinology United States, 2022 May 1; 163 (5):Journal ArticleEffects of the Isolated and Combined Ablation of Growth Hormone and IGF-1 Receptors in Somatostatin Neurons
DOI:10.1210/endocr/bqac045 PMID: 35395079 -
Cara AL, Henson EL, Beekly BG, Elias CF. Journal of Neuroendocrinology, 2021 Dec 1; 33 (12):Journal ArticleDistribution of androgen receptor mRNA in the prepubertal male and female mouse brain
DOI:10.1111/jne.13063 PMID: 34866263