ChadTough Defeat DIPG Research Professor of Pediatrics
Associate Professor of Pediatrics
[email protected]
Available to mentor
Carl Koschmann
Associate Professor
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Center MemberRogel Cancer Center
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Roberts HJ, Ji S, Picca A, Sanson M, Garcia M, Snuderl M, Schüller U, Picart T, Ducray F, Green AL, Nakano Y, Sturm D, Abdullaev Z, Aldape K, Dang D, Kumar-Sinha C, Wu Y-M, Robinson D, Vo JN, Chinnaiyan AM, Cartaxo R, Upadhyaya SA, Mody R, Chiang J, Baker S, Solomon D, Venneti S, Pratt D, Waszak SM, Koschmann C. Acta Neuropathol, 2023 Dec; 146 (6): 849 - 852.Journal ArticleClinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations.
DOI:10.1007/s00401-023-02640-7 PMID: 37851269 -
Xin DE, Liao Y, Rao R, Ogurek S, Sengupta S, Xin M, Seibel WL, Graham RT, Koschmann C, Lu QR. Neuro Oncol, 2023 Nov 27;Journal ArticleChaetocin-mediated SUV39H1 inhibition targets stemness and oncogenic networks of diffuse midline gliomas and synergizes with ONC201.
DOI:10.1093/neuonc/noad222 PMID: 38011799 -
Koschmann C, Al-Holou WN, Alonso MM, Anastas J, Bandopadhayay P, Barron T, Becher O, Cartaxo R, Castro MG, Chung C, Clausen M, Dang D, Doherty R, Duchatel R, Dun M, Filbin M, Franson A, Galban S, Garcia Moure M, Garton H, Gowda P, Marques JG, Hawkins C, Heath A, Hulleman E, Ji S, Jones C, Kilburn L, Kline C, Koldobskiy MA, Lim D, Lowenstein PR, Lu QR, Lum J, Mack S, Magge S, Marini B, Martin D, Marupudi N, Messinger D, Mody R, Morgan M, Mota M, Muraszko K, Mueller S, Natarajan SK, Nazarian J, Niculcea M, Nuechterlein N, Okada H, Opipari V, Pai MP, Pal S, Peterson E, Phoenix T, Prensner JR, Pun M, Raju GP, Reitman ZJ, Resnick A, Rogawski D, Saratsis A, Sbergio SG, Souweidane M, Stafford JM, Tzaridis T, Venkataraman S, Vittorio O, Wadden J, Wahl D, Wechsler-Reya RJ, Yadav VN, Zhang X, Zhang Q, Venneti S. Cancer Cell, 2023 Nov 20;Journal ArticleA road map for the treatment of pediatric diffuse midline glioma.
DOI:10.1016/j.ccell.2023.11.002 PMID: 38039965 -
Ausejo-Mauleon I, Labiano S, de la Nava D, Laspidea V, Zalacain M, Marrodán L, García-Moure M, González-Huarriz M, Hervás-Corpión I, Dhandapani L, Vicent S, Collantes M, Peñuelas I, Becher OJ, Filbin MG, Jiang L, Labelle J, de Biagi-Junior CAO, Nazarian J, Laternser S, Phoenix TN, van der Lugt J, Kranendonk M, Hoogendijk R, Mueller S, De Andrea C, Anderson AC, Guruceaga E, Koschmann C, Yadav VN, Gállego Pérez-Larraya J, Patiño-García A, Pastor F, Alonso MM. Cancer Cell, 2023 Nov 13; 41 (11): 1911 - 1926.e8.Journal ArticleTIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.
DOI:10.1016/j.ccell.2023.09.001 PMID: 37802053 -
Erez N, Furth N, Fedyuk V, Wadden J, Aittaleb R, Schwark K, Miclea M, Venneti S, Koschmann C, Shema E. Neuro-Oncology, 2023 Nov 10; 25 (Supplement_5): v5 - v5.Journal ArticleBIOM-08. SINGLE-MOLECULE SYSTEMS FOR DETECTION OF PLASMA CIRCULATING ONCOPROTEINS IN DIFFUSE MIDLINE GLIOMA
DOI:10.1093/neuonc/noad179.0019 -
Wadden J, John V, Niculcea M, Kong S, Aittaleb R, Cartaxo R, Verbal K, Bruzek A, Magge S, Yadavilli S, Erez N, Furth N, Shema E, Marapudi N, Heth J, Al-holou W, Garton H, Nazarian J, Koschmann C. Neuro-Oncology, 2023 Nov 10; 25 (Supplement_5): v17 - v18.Journal ArticleBIOM-58. ZERO-WASTE MOLECULAR DIAGNOSTICS FROM BIOPSY NEEDLE WASHES
DOI:10.1093/neuonc/noad179.0069 -
Barravecchia I, Sharma M, Teis R, Cruz J, Mumby R, Ziemke E, Espinoza C, Krishnamoorthy V, Magnuson B, Ljungman M, Koschmann C, Whitehead C, Sebolt-Leopold J, Galban S. Neuro-Oncology, 2023 Nov 10; 25 (Supplement_5): v105 - v106.Journal ArticleDDDR-05. TARGETED INHIBITION OF DNA REPAIR AND SURVIVAL SIGNALING IN DIFFUSE INTRINSIC PONTINE GLIOMAS
DOI:10.1093/neuonc/noad179.0399 -
Venneti S, Kawakibi AR, Ji S, Waszak SM, Sweha SR, Mota M, Pun M, Deogharkar A, Chung C, Tarapore RS, Ramage S, Chi A, Wen PY, Arrillaga-Romany I, Batchelor TT, Butowski NA, Sumrall A, Shonka N, Harrison RA, de Groot J, Mehta M, Hall MD, Daghistani D, Cloughesy TF, Ellingson BM, Beccaria K, Varlet P, Kim MM, Umemura Y, Garton H, Franson A, Schwartz J, Jain R, Kachman M, Baum H, Burant CF, Mottl SL, Cartaxo RT, John V, Messinger D, Qin T, Peterson E, Sajjakulnukit P, Ravi K, Waugh A, Walling D, Ding Y, Xia Z, Schwendeman A, Hawes D, Yang F, Judkins AR, Wahl D, Lyssiotis CA, de la Nava D, Alonso MM, Eze A, Spitzer J, Schmidt SV, Duchatel RJ, Dun MD, Cain JE, Jiang L, Stopka SA, Baquer G, Regan MS, Filbin MG, Agar NYR, Zhao L, Kumar-Sinha C, Mody R, Chinnaiyan A, Kurokawa R, Pratt D, Yadav VN, Grill J, Kline C, Mueller S, Resnick A, Nazarian J, Allen JE, Odia Y, Gardner SL, Koschmann C. 2023 Nov 1;Additional ScholarshipData from Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
DOI:10.1158/2159-8290.c.6908476