Erin E Perrone, MD
Clinical Associate Professor of Surgery and Medical Director
UMMG
Pediatric Surgery Clinic
1540 E Hospital Drive, Floor 4 Reception B
Ann Arbor, MI 48109
[email protected]

Available to mentor

Erin E Perrone, MD
Clinical Associate Professor
  • About
  • Links
  • Qualifications
  • Research Overview
  • Recent Publications
  • About

    Erin E. Perrone, MD is a faculty member in the Section of Pediatric Surgery. She received her medical degree from Wayne State University and her general surgery training at the Detroit Medical Center/Wayne State University Department of Surgery. She completed pediatric surgery fellowship at Loma Linda University Children’s Hospital. She is board certified in Pediatric and General Surgery.

    Dr. Perrone is part of the Fetal Diagnosis and Treatment Center (FDTC) team and is specialized in prenatal consultation with evaluation for potential fetal intervention. Her practice includes all areas of general pediatric surgery with specific interest in congenital malformations and neonatal surgical diseases. She is active in clinical research and serves as the site principal investigator for 2 clinical trials, one for timing of delivery in gastroschisis and the other for fetal endoscopic tracheal occlusion (FETO), directed at prenatal therapy for congenital diaphragmatic hernia.

    Dr. Perrone has served the department as one of the inaugural co-chairs of the Junior Faculty Advisory Committee (JFAC), co-founder of the Impacting Health Equity, Opportunity, Pipeline, and Education (HOPE) Collaborative, and lead of the Michigan Women’s Surgical Collaborative (MWSC). She is also the Vice Chair of Faculty Life which manages the facets of the Michigan Promise, an initiative to ensure each and every faculty member reaches his or her fullest potential. Her leadership is also recognized outside of our department as she is a co-chair of the Michigan Medicine Professionalism Committee and has served as the co-chair for the inaugural women in surgery committees for both the American Pediatric Surgery Association (APSA) and the Michigan Chapter of the American College of Surgeons (MCACS). She has a passion for improving our work environment and developing an inclusive culture.

    Links
    • https://www.uofmhealth.org/profile/4069/erin-elizabeth-perrone-md
    Qualifications
    • Pediatric Surgery Fellow
      Loma Linda University Children's Hospital, Loma Linda, 2015
    • General Surgery Categorical Resident
      Detroit Medical Center, General Surgery, 2012
    Research Overview

    Dr. Perrone's research passion is in fetal intervention. She's dedicated to the improvement of care in fetuses and neonates in the perinatal period. She is an active member of the Fetal Diagnosis and Treatment Center (FDTC) team at Michigan Medicine and is the principal investigator (PI) and sponsor for our Fetal Endoscopic Tracheal Occlusion (FETO) trial through an FDA-approved Investigational Device Exemption (IDE). This is a clinical feasibility trial that offers prenatal therapy for fetuses with the most severe form of CDH designed to increase fetal lung tissue with the potential to improve survival postnatally. She also serves as site PI for Gastroschisis Outcomes of Delivery (GOOD) study, a clinical trial evaluating the impact of timing of delivery in fetuses with known gastroschisis so have experience with clinical trials.

    Dr. Perrone previously led a multi-institutional review of closing gastroschisis. This review identified 53 patients and developed a new classification system for postnatal grouping of these challenging patients and provided long-term data for physicians to use for counseling. She has also collaborated with other institutions investigating clinical outcomes surrounding the care of infants with gastroschisis.

    Dr. Perrone has been actively involved in clinical research surrounding CDH outcomes and improving the ability to provide prognosis for families prenatally. She's successfully collaborated with members of the Congenital Diaphragmatic Hernia Study Group (CDHSG) as well as the North American Fetal Therapy Network (NAFTNet) to improve knowledge of CDH.

    Dr. Perrone has focused on review of fetuses that have prenatally identified anomalies and outcomes with or without fetal intervention. These have added to the current literature and outline clinical recommendations for other fetal surgeons.

    Prenatal Diagnosis, Therapy, and Fetal Intervention
    Quality Improvement in Perinatal and Neonatal Care
    Congenital Diaphragmatic Hernia
    Gastroschisis
    Fetal Blood Banking and Transfusion of Fetal Red Blood Cells
    Creation of a Novel Prenatal Hysterotomy

    Recent Publications See All Publications
    • Journal Article
      Preoperative virtual video visits only: a convenient option that should be offered to caregivers beyond the pandemic.
      Dougherty D, Thompson AR, Speck KE, Perrone EE. World J Pediatr Surg, 2022 5 (3): e000403 DOI:10.1136/wjps-2021-000403
      PMID: 36475053
    • Journal Article
      Patterns and Outcomes of Epoprostenol Use in Infants with Congenital Diaphragmatic Hernia Requiring Extracorporeal Life Support.
      Shah NR, Burgi K, Lotakis DM, Olive MK, McCormick AD, Perrone EE, Church JT, Mychaliska GB. J Pediatr, 2024 Sep 2; 276: 114286 DOI:10.1016/j.jpeds.2024.114286
      PMID: 39233115
    • Journal Article
      Patterns and Outcomes of Epoprostenol Use in Infants with Congenital Diaphragmatic Hernia Requiring Extracorporeal Life Support.
      Shah NR, Burgi K, Lotakis DM, Olive MK, McCormick AD, Perrone EE, Church JT, Mychaliska GB. J Pediatr, 2024 Sep 2; 276: 114286 DOI:10.1016/j.jpeds.2024.114286
      PMID: 39233115
    • Presentation
      Changing Surgical Culure: “Health Equity, The Michigan Promise, & HOPE Collaborative”
      Perrone E. 2024 Jun 1;
    • Presentation
      Fetal Endoscopic Tracheal Occlusion (FETO) – History, Indications, & Lessons Learned
      Perrone E. 2024 Jun;
    • Journal Article
      Thoracoscopic Patch Repair of Congenital Diaphragmatic Hernia: Can Smaller Incisions Treat Larger Defects?
      Shah NR, Criss CN, Burgi K, Matusko N, Geiger JD, Perrone EE, Mychaliska GB, Ralls MW. J Pediatr Surg, 2024 Jun; 59 (6): 1083 - 1088. DOI:10.1016/j.jpedsurg.2023.09.040
      PMID: 37867043
    • Presentation
      The Impact of Health Policy Change on Moral Distress in Pediatric Surgeons
      2024 May 16;
    • Journal Article
      The role of fetal hemoglobin in the artificial placenta: A premature ovine model.
      Spencer BL, Fallon BP, McLeod JS, Cornell M, Perrone EE, Manthei DM, Rojas-Peña A, Hirschl RB, Bartlett RH, Mychaliska GB. Perfusion, 2024 Mar 22; 2676591241240725 DOI:10.1177/02676591241240725
      PMID: 38519444
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