Zirui Huang
Research Assistant Professor
[email protected]

Available to mentor

Zirui Huang
Research Assistant Professor
  • About
  • Qualifications
  • Research Overview
  • Recent Publications
  • About

    I am a Research Assistant Professor in the Department of Anesthesiology and a member of the Center for Consciousness Science at the University of Michigan Medical School. I have a multidisciplinary background including psychology, biology, cognitive neuroscience, and neuroimaging. I study the mechanistic role of large-scale brain networks in conscious cognition and its alteration by pharmacologic, neuropathologic and psychiatric manipulations using functional magnetic resonance imaging (fMRI).

    • Postdoctoral Research Fellow
      University of Michigan Medical School, Department of Anesthesiology, 2018
    • Postdoctoral Fellow
      University of Ottawa, Institute of Mental Health Research, 2016
    • PhD
      Institute of Psychology, Chinese Academy of Sciences, Beijing, 2012
    • BS
      Department of Biology, China Agriculture University, Beijing, 2007
    Research Overview

    The neural substrates of consciousness, e.g., the boundaries between conscious and non-conscious processing.
    Neural signatures in human subjects during awake, anesthesia, vegetative state, and mental/cognitive disorders.
    Spatiotemporal configurations and alterations of large-scale brain dynamics.
    Perceptual awareness.

    Recent Publications See All Publications
    • Preprint
      Propofol Disrupts the Functional Core-Matrix Architecture of the Thalamus in Humans.
      Huang Z, Mashour GA, Hudetz AG. 2024 Jan 24; DOI:10.1101/2024.01.23.576934
      PMID: 38328136
    • Journal Article
      The neural correlates of arousal: Ventral posterolateral nucleus-global transient co-activation.
      Han J, Xie Q, Wu X, Huang Z, Tanabe S, Fogel S, Hudetz AG, Wu H, Northoff G, Mao Y, He S, Qin P. Cell Rep, 2024 Jan 23; 43 (1): 113633 DOI:10.1016/j.celrep.2023.113633
      PMID: 38159279
    • Journal Article
      Altered brain dynamics index levels of arousal in complete locked-in syndrome.
      Zilio F, Gomez-Pilar J, Chaudhary U, Fogel S, Fomina T, Synofzik M, Schöls L, Cao S, Zhang J, Huang Z, Birbaumer N, Northoff G. Commun Biol, 2023 Jul 20; 6 (1): 757 DOI:10.1038/s42003-023-05109-1
      PMID: 37474587
    • Journal Article
      Functional geometry of the cortex encodes dimensions of consciousness.
      Huang Z, Mashour GA, Hudetz AG. Nat Commun, 2023 Jan 5; 14 (1): 72 DOI:10.1038/s41467-022-35764-7
      PMID: 36604428
    • Journal Article
      Psychedelic concentrations of nitrous oxide reduce functional differentiation in frontoparietal and somatomotor cortical networks.
      Dai R, Huang Z, Larkin TE, Tarnal V, Picton P, Vlisides PE, Janke E, McKinney A, Hudetz AG, Harris RE, Mashour GA. Commun Biol, 2023 Dec 19; 6 (1): 1284 DOI:10.1038/s42003-023-05678-1
      PMID: 38114805
    • Journal Article
      Scale-free dynamics in the core-periphery topography and task alignment decline from conscious to unconscious states.
      Klar P, Çatal Y, Langner R, Huang Z, Northoff G. Commun Biol, 2023 May 9; 6 (1): 499 DOI:10.1038/s42003-023-04879-y
      PMID: 37161021
    • Journal Article
      Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex.
      Chen A, Sun Y, Lei Y, Li C, Liao S, Meng J, Bai Y, Liu Z, Liang Z, Zhu Z, Yuan N, Yang H, Wu Z, Lin F, Wang K, Li M, Zhang S, Yang M, Fei T, Zhuang Z, Huang Y, Zhang Y, Xu Y, Cui L, Zhang R, Han L, Sun X, Chen B, Li W, Huangfu B, Ma K, Ma J, Li Z, Lin Y, Wang H, Zhong Y, Zhang H, Yu Q, Wang Y, Liu X, Peng J, Liu C, Chen W, Pan W, An Y, Xia S, Lu Y, Wang M, Song X, Liu S, Wang Z, Gong C, Huang X, Yuan Y, Zhao Y, Chai Q, Tan X, Liu J, Zheng M, Li S, Huang Y, Hong Y, Huang Z, Li M, Jin M, Li Y, Zhang H, Sun S, Gao L, Bai Y, Cheng M, Hu G, Liu S, Wang B, Xiang B, Li S, Li H, Chen M, Wang S, Li M, Liu W, Liu X, Zhao Q, Lisby M, Wang J, Fang J, Lin Y, Xie Q, Liu Z, He J, Xu H, Huang W, Mulder J, Yang H, Sun Y, Uhlen M, Poo M, Wang J, Yao J, Wei W, Li Y, Shen Z, Liu L, Liu Z, Xu X, Li C. Cell, 2023 Aug 17; 186 (17): 3726 - 3743.e24. DOI:10.1016/j.cell.2023.06.009
      PMID: 37442136
    • Journal Article
      Temporospatial Nestedness in Consciousness: An Updated Perspective on the Temporospatial Theory of Consciousness.
      Huang Z. Entropy (Basel), 2023 Jul 17; 25 (7): DOI:10.3390/e25071074
      PMID: 37510023