Peter DR Higgins, MD, PhD, MSc(CRDSA), AGAF
Timothy T Nostrant M.D.
Collegiate Professor of Gastroenterology
Professor of Internal Medicine
[email protected]

Available to mentor

Peter DR Higgins, MD, PhD, MSc(CRDSA), AGAF
Professor
  • About
  • Links
  • Research Overview
  • Recent Publications
  • About

    Dr. Peter Higgins received his bachelor's degree and medical degrees from Duke University, and completed a Ph.D. in molecular cancer biology at Duke. He completed a fellowship in gastroenterology at the University of Michigan in 2004, completed an M.Sc. in Clinical Research Design and Statistical Analysis at the University of Michigan School of Public Health, and joined the University of Michigan faculty the same year. Dr. Higgins currently serves as the IBD editor for the American Journal of Gastroenterology. His research focuses on inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis. He is interested in the molecular mechanisms of intestinal fibrosis, which leads to intestinal blockages and surgery. Dr. Higgins studies the use of ultrasound to measure intestinal scarring, the use of biomarkers to detect early scarring, and measurement of markers of early inflammation. His clinical research includes studies on patient-reported outcomes in IBD, medication holidays after long-term remission in IBD, and biomarker-guided therapy in IBD. Dr. Higgins' research interests are complemented by his clinical interest in improving the quality of care of patients with IBD. He is a member of the AGA IBD Quality Measures Committee, and has participated in the development of national guidelines for high quality IBD care. Dr. Higgins has received many honors and awards, including the AGA IBD Clinical Research Excellence Award.

    Links
    • Higgins IBD Program
    Research Overview

    Detection and measurement of inflammation in inflammatory bowel disease (IBD). Mechanisms of intestinal fibrosis, and measurement of fibrosis with ultrasound and biomarkers. Medication holidays after long-term IBD remission. Patient-reported outcomes in IBD.

    Recent Publications See All Publications
    • Journal Article
      Effectiveness of Upadacitinib for Patients With Acute Severe Ulcerative Colitis: A Multicenter Experience.
      Berinstein JA, Karl T, Patel A, Dolinger M, Barrett TA, Ahmed W, Click B, Steiner CA, Dulaney D, Levine J, Hassan SA, Perry C, Flomenhoft D, Ungaro RC, Berinstein EM, Sheehan J, Cohen-Mekelburg S, Regal RE, Stidham RW, Bishu S, Colombel J-F, Higgins PDR. Am J Gastroenterol, 2024 Mar 27; DOI:10.14309/ajg.0000000000002674
      PMID: 38275248
    • Journal Article
      Long-Term Effectiveness and Durability of COVID-19 Vaccination Among Patients With Inflammatory Bowel Disease.
      Brenner EJ, Weaver KN, Zhang X, Kastl AJ, Strople JA, Adler J, Dubinsky MC, Bousvaros A, Watkins R, Dai X, Chen W, Cross RK, Higgins PDR, Ungaro RC, Bewtra M, Bellaguarda EA, Farraye FA, Chun KY, Zikry M, Bastidas M, Firestine A, Craig RG, Boccieri ME, Long MD, Kappelman MD. Clin Gastroenterol Hepatol, 2024 Jul; 22 (7): 1475 - 1486.e4. DOI:10.1016/j.cgh.2024.02.001
      PMID: 38369224
    • Journal Article
      Timing Is Everything: The Lifesaving Potential of Early Medical Therapy in Acute Severe Ulcerative Colitis.
      Kathuria P, Higgins PDR, Berinstein JA. Am J Gastroenterol, 2024 Jun 12; DOI:10.14309/ajg.0000000000002867
      PMID: 38864521
    • Proceeding / Abstract / Poster
      P120 Upadacitinib for moderate-to-severe ulcerative colitis: interim results from U-ACTIVATE phase III open-label extension
      Panaccione R, Higgins PD, Lichtenstein G, Nakase H, Kujawski M, Cheng E, Ilo D, Levy G, Eccleston J, Glover SC, Danese S, Colombel J-F, Schreiber S, Terai A. 2024 Jun; a123.1 - a1a123. DOI:10.1136/gutjnl-2024-bsg.202
    • Journal Article
      Predictors of irritable bowel syndrome-like symptoms in quiescent inflammatory bowel disease.
      Ahmed M, Pu A, Jencks K, Bishu S, Higgins P, Chey WD, Rao K, Lee A. Neurogastroenterol Motil, 2024 Jun; 36 (6): e14809 DOI:10.1111/nmo.14809
      PMID: 38651743
    • Chapter
      Internal Fistula, Abscesses, and Strictures
      Higgins PDR. Clinical Challenges and Complications of IBD, 17 - 41. DOI:10.1201/9781003523017-3
    • Journal Article
      Legalization of Cannabis Does Not Reduce Opioid Prescribing in Patients With Inflammatory Bowel Disease: A Difference-in-Difference Analysis.
      Noureldin M, Van T, Cohen-Mekelburg S, Scott FI, Higgins PDR, Stidham RW, Hou J, Waljee AK, Berinstein JA. Am J Gastroenterol, 2024 May 21; DOI:10.14309/ajg.0000000000002834
      PMID: 38767951
    • Journal Article
      Insurer-Mandated Medication Utilization Barriers are Associated With Decreased Insurance Satisfaction and Adverse Clinical Outcomes: An Inflammatory Bowel Disease Partners Survey.
      Constant BD, Long MD, Scott FI, Higgins PDR. Am J Gastroenterol, 2024 May 2; DOI:10.14309/ajg.0000000000002851
      PMID: 38819004