Sebastian K Zoellner
John G Searle Associate Professor of Biostatistics
Professor of Biostatistics
Professor of Psychiatry
[email protected]

Available to mentor

Sebastian K Zoellner
Professor
  • Center Memberships
  • Recent Publications
  • Center Memberships
    • Center Member
      Eisenberg Family Depression Center
    • Center Member
      Precision Health Initiative
    • Center Member
      Center for Computational Medicine and Bioinformatics
    Recent Publications See All Publications
    • Journal Article
      FICTURE: scalable segmentation-free analysis of submicron-resolution spatial transcriptomics.
      Si Y, Lee C, Hwang Y, Yun JH, Cheng W, Cho C-S, Quiros M, Nusrat A, Zhang W, Jun G, Zöllner S, Lee JH, Kang HM. Nat Methods, 2024 Oct; 21 (10): 1843 - 1854. DOI:10.1038/s41592-024-02415-2
      PMID: 39266749
    • Journal Article
      Multi-ancestry polygenic risk scores for venous thromboembolism.
      Jee YH, Thibord F, Dominguez A, Sept C, Boulier K, Venkateswaran V, Ding Y, Cherlin T, Verma SS, Faro VL, Bartz TM, Boland A, Brody JA, Deleuze J-F, Emmerich J, Germain M, Johnson AD, Kooperberg C, Morange P-E, Pankratz N, Psaty BM, Reiner AP, Smadja DM, Sitlani CM, Suchon P, Tang W, Trégouët D-A, Zöllner S, Pasaniuc B, Damrauer SM, Sanna S, Snieder H, Lifelines Cohort Study , Kabrhel C, Smith NL, Kraft P, INVENT Consortium . Hum Mol Genet, 2024 Sep 3; 33 (18): 1584 - 1591. DOI:10.1093/hmg/ddae097
      PMID: 38879759
    • Preprint
      The expected polygenic risk score (ePRS) framework: an equitable metric for quantifying polygenetic risk via modeling of ancestral makeup
      Huang Y-J, Kurniansyah N, Goodman MO, Spitzer BW, Wang J, Stilp A, Laurie C, de Vries PS, Chen H, Min Y-I, Sims M, Peloso GM, Guo X, Bis JC, Brody JA, Raffield LM, Smith JA, Zhao W, Rotter JI, Rich SS, Redline S, Fornage M, Kaplan R, Franceschini N, Levy D, Morrison AC, Boerwinkle E, Smith NL, Kooperberg C, Psaty BM, Zöllner S, Consortium TT-OIPM, Sofer T. medRxiv, DOI:10.1101/2024.03.05.24303738
    • Journal Article
      PNPLA3 Risk Allele Association With ALT Response to Semaglutide Treatment.
      Urias E, Tedesco NR, Oliveri A, Raut C, Michigan Genomics Initiative , Speliotes EK, Chen VL. Gastroenterology, 2024 Mar; 166 (3): 515 - 517.e2. DOI:10.1053/j.gastro.2023.11.018
      PMID: 37972824
    • Journal Article
      Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
      Ziyatdinov A, Torres J, Alegre-Díaz J, Backman J, Mbatchou J, Turner M, Gaynor SM, Joseph T, Zou Y, Liu D, Wade R, Staples J, Panea R, Popov A, Bai X, Balasubramanian S, Habegger L, Lanche R, Lopez A, Maxwell E, Jones M, García-Ortiz H, Ramirez-Reyes R, Santacruz-Benítez R, Nag A, Smith KR, Damask A, Lin N, Paulding C, Reppell M, Zöllner S, Jorgenson E, Salerno W, Petrovski S, Overton J, Reid J, Thornton TA, Abecasis G, Berumen J, Orozco-Orozco L, Collins R, Regeneron Genetics Center , Mexico City Prospective Study , Baras A, Hill MR, Emberson JR, Marchini J, Kuri-Morales P, Tapia-Conyer R. Nature, 2024 Feb; 626 (8001): E18 DOI:10.1038/s41586-024-07051-6
      PMID: 38332034
    • Preprint
      A Stacking Framework for Polygenic Risk Prediction in Admixed Individuals.
      Liao K, Zöllner S. 2024 Feb 3; DOI:10.1101/2024.01.31.24302103
      PMID: 38434717
    • Preprint
      Multi-ancestry polygenic risk scores for venous thromboembolism.
      Jee YH, Thibord F, Dominguez A, Sept C, Boulier K, Venkateswaran V, Ding Y, Cherlin T, Verma SS, Faro VL, Bartz TM, Boland A, Brody JA, Deleuze J-F, Emmerich J, Germain M, Johnson AD, Kooperberg C, Morange P-E, Pankratz N, Psaty BM, Reiner AP, Smadja DM, Sitlani CM, Suchon P, Tang W, Trégouët D-A, Zöllner S, Pasaniuc B, Damrauer SM, Sanna S, Snieder H, Lifelines Cohort Study , Kabrhel C, Smith NL, Kraft P, INVENT Consortium . 2024 Jan 10; DOI:10.1101/2024.01.09.24300914
      PMID: 38260294
    • Journal Article
      Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.
      Wang A, Shen J, Rodriguez AA, Saunders EJ, Chen F, Janivara R, Darst BF, Sheng X, Xu Y, Chou AJ, Benlloch S, Dadaev T, Brook MN, Plym A, Sahimi A, Hoffman TJ, Takahashi A, Matsuda K, Momozawa Y, Fujita M, Laisk T, Figuerêdo J, Muir K, Ito S, Liu X, Biobank Japan Project , Uchio Y, Kubo M, Kamatani Y, Lophatananon A, Wan P, Andrews C, Lori A, Choudhury PP, Schleutker J, Tammela TLJ, Sipeky C, Auvinen A, Giles GG, Southey MC, MacInnis RJ, Cybulski C, Wokolorczyk D, Lubinski J, Rentsch CT, Cho K, Mcmahon BH, Neal DE, Donovan JL, Hamdy FC, Martin RM, Nordestgaard BG, Nielsen SF, Weischer M, Bojesen SE, Røder A, Stroomberg HV, Batra J, Chambers S, Horvath L, Clements JA, Tilly W, Risbridger GP, Gronberg H, Aly M, Szulkin R, Eklund M, Nordstrom T, Pashayan N, Dunning AM, Ghoussaini M, Travis RC, Key TJ, Riboli E, Park JY, Sellers TA, Lin H-Y, Albanes D, Weinstein S, Cook MB, Mucci LA, Giovannucci E, Lindstrom S, Kraft P, Hunter DJ, Penney KL, Turman C, Tangen CM, Goodman PJ, Thompson IM, Hamilton RJ, Fleshner NE, Finelli A, Parent M-É, Stanford JL, Ostrander EA, Koutros S, Beane Freeman LE, Stampfer M, Wolk A, Håkansson N, Andriole GL, Hoover RN, Machiela MJ, Sørensen KD, Borre M, Blot WJ, Zheng W, Yeboah ED, Mensah JE, Lu Y-J, Zhang H-W, Feng N, Mao X, Wu Y, Zhao S-C, Sun Z, Thibodeau SN, McDonnell SK, Schaid DJ, West CML, Barnett G, Maier C, Schnoeller T, Luedeke M, Kibel AS, Drake BF, Cussenot O, Cancel-Tassin G, Menegaux F, Truong T, Koudou YA, John EM, Grindedal EM, Maehle L, Khaw K-T, Ingles SA, Stern MC, Vega A, Gómez-Caamaño A, Fachal L, Rosenstein BS, Kerns SL, Ostrer H, Teixeira MR, Paulo P, Brandão A, Watya S, Lubwama A, Bensen JT, Butler EN, Mohler JL, Taylor JA, Kogevinas M, Dierssen-Sotos T, Castaño-Vinyals G, Cannon-Albright L, Teerlink CC, Huff CD, Pilie P, Yu Y, Bohlender RJ, Gu J, Strom SS, Multigner L, Blanchet P, Brureau L, Kaneva R, Slavov C, Mitev V, Leach RJ, Brenner H, Chen X, Holleczek B, Schöttker B, Klein EA, Hsing AW, Kittles RA, Murphy AB, Logothetis CJ, Kim J, Neuhausen SL, Steele L, Ding YC, Isaacs WB, Nemesure B, Hennis AJM, Carpten J, Pandha H, Michael A, De Ruyck K, De Meerleer G, Ost P, Xu J, Razack A, Lim J, Teo S-H, Newcomb LF, Lin DW, Fowke JH, Neslund-Dudas CM, Rybicki BA, Gamulin M, Lessel D, Kulis T, Usmani N, Abraham A, Singhal S, Parliament M, Claessens F, Joniau S, Van den Broeck T, Gago-Dominguez M, Castelao JE, Martinez ME, Larkin S, Townsend PA, Aukim-Hastie C, Bush WS, Aldrich MC, Crawford DC, Srivastava S, Cullen J, Petrovics G, Casey G, Wang Y, Tettey Y, Lachance J, Tang W, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Yamoah K, Govindasami K, Chokkalingam AP, Keaton JM, Hellwege JN, Clark PE, Jalloh M, Gueye SM, Niang L, Ogunbiyi O, Shittu O, Amodu O, Adebiyi AO, Aisuodionoe-Shadrach OI, Ajibola HO, Jamda MA, Oluwole OP, Nwegbu M, Adusei B, Mante S, Darkwa-Abrahams A, Diop H, Gundell SM, Roobol MJ, Jenster G, van Schaik RHN, Hu JJ, Sanderson M, Kachuri L, Varma R, McKean-Cowdin R, Torres M, Preuss MH, Loos RJF, Zawistowski M, Zöllner S, Lu Z, Van Den Eeden SK, Easton DF, Ambs S, Edwards TL, Mägi R, Rebbeck TR, Fritsche L, Chanock SJ, Berndt SI, Wiklund F, Nakagawa H, Witte JS, Gaziano JM, Justice AC, Mancuso N, Terao C, Eeles RA, Kote-Jarai Z, Madduri RK, Conti DV, Haiman CA. Nat Genet, 2023 Dec; 55 (12): 2065 - 2074. DOI:10.1038/s41588-023-01534-4
      PMID: 37945903