Anna Suk-Fong Lok, MD

Anna S. Lok
Dame Sheila Sherlock Distinguished University Professor of Hepatology and Internal Medicine
Alice Lohrman Andrews Research Professor of Hepatology
Professor of Internal Medicine
Assistant Dean for Clinical Research
Medical School
University of Michigan Medical School
Internal Medicine, Division of Gastroenterology and Hepatology
1500 East Medical Center Drive
Ann Arbor, MI 48109
[email protected]
Available to mentor
Anna Suk-Fong Lok, MD
Anna S. Lok
Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    Anna Suk-Fong Lok, M.D., is director of clinical hepatology and assistant dean for clinical research at the University of Michigan Medical School. She also is the Dame Sheila Sherlock Distinguished University Professor of Hepatology and Internal Medicine and Alice Lohrman Andrews Research Professor of Hepatology in the Department of Internal Medicine.

    In her role as assistant dean, Dr. Lok is responsible for leading, championing, and implementing recommendations from the Research Board of Directors to transform the clinical trials enterprise of the academic medical center. She is responsible for the overall leadership and direction, management, and oversight of the Clinical Trials Support Units and the Clinical Research Unit, training of clinical investigators, and facilitation and support of clinical research.

    Dr. Lok obtained her medical degree from the University of Hong Kong and her hepatology training under the late Dame Sheila Sherlock at the Royal Free Hospital in London, UK. She was on the faculty at the University of Hong Kong until she moved to the United States in 1992.

    Her research focuses on the natural history and treatment of hepatitis B and C, and the prevention of liver cancer. Her research is funded by the National Institutes of Health, federal and private foundations, and various pharmaceutical companies. She has published more than 600 papers on viral hepatitis and liver diseases and is the co-author of five editions of the American Association for the Study of Liver Diseases Association Guidelines on Hepatitis B. She was one of the top 1% most cited scientists in the world for the decade 2002-12. She has trained more than 60 fellows and junior faculty from all over the world, some of whom have risen to the ranks of full professors and directors of liver programs in their home country. She received a Distinguished Mentor Award from the Michigan Institute of Clinical and Health Research in 2012, an Inspirational Physician Award from the American Medical Association in 2014, and a Distinguished Mentor Award from the American Gastroenterological Association in 2022. She was inducted into the Clinical Excellence Society in the Department of Internal Medicine in 2013.

    Dr. Lok has received many awards throughout her career. She has been included in the list of “Best Doctors” and “Who's Who” for many years. She was inducted into the Association of American Physicians in 2012 and elected to the National Academy of Medicine in 2022. Recent awards include the Distinguished Scientist Award from the Hepatitis B Foundation in 2008, the Distinguished Women Scientist Award from the American Gastroenterological Association in 2008, the Distinguished Service Award from the American Association for the Study of Liver Diseases in 2011, the Distinguished Scientific Achievement Award from the American Liver Foundation in 2015, the William Beaumont Prize in Gastroenterology from the American Gastroenterological Association in 2016, a Gold Medal Award from the Canadian Association for the Study of the Liver and an honorary Doctor of Science degree from the University of Hong Kong in 2017, the International Recognition Award from the European Association of the Study of the Liver in 2018, and a Distinguished University Professorship from the University of Michigan in 2019.

    She is currently an associate editor of Hepatology Communication. She was an associate editor of HEPATOLOGY from 2001-06, a co-editor of the Journal of Viral Hepatitis from 2007-09, and a senior associate editor of GASTROENTEROLOGY from 2011-12.

    Dr. Lok was the President of the American Association for the Study of Liver Diseases in 2017.

    Qualifications

    • MD
      University of Hong Kong, Hong Kong, United Kingdom
      1990 - 1990
    • MB BS
      University of Hong Kong School of Medicine, Hong Kong, United Kingdom
      1972 - 1977

    Center Memberships

    • Center Member
      MM-PKUHSC Joint Institute
    • Center Member
      Rogel Cancer Center
    • Center Member
      Global REACH
    • Center Member
      Institute for Healthcare Policy and Innovation

    Research Overview

    Epidemiology, natural history, and treatment of hepatitis B and C
    Risk stratification of nonalcoholic fatty liver disease
    Prevention and early detection of hepatocellular carcinoma

    Recent Publications

    See All Publications
    • Journal Article
      Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits
      Han Y, Shaw VR, Byun J, Thrift AP, Zhu C, Li D, Hatia RI, Kelley RK, Cleary SP, Lok AS, Bracci PM, Permuth JB, Bucur R, Knox J, Yuan JM, Singal AG, Jalal PK, Ghobrial RM, Kono Y, Shah DP, Nguyen MH, Parikh ND, Kim R, Wu HC, El-Serag H, Chang P, Chun YS, Gu J, Huff C, Rashid A, Hwang LY, Klein AP, Khaderi SA, Kaseb AO, McGlynn KA, Roberts LR, Hassan MM, Amos CI. International Journal of Cancer, 2026 Mar 1; 158 (5): 1193 - 1203. DOI:10.1002/ijc.70136
      PMID: 41013983
    • Journal Article
      Validation of longitudinal biomarker screening algorithms for HCC detection in patients with cirrhosis.
      Singal AG, Jin Q, Marrero J, Parikh ND, Lok AS, Lopez C, Page-Lester S, Roberts LR, Reddy R, Luster M, Khaderi S, Asrani SK, El-Serag HB, Kanwal F, Feng Z, Tayob N. Hepatol Commun, 2026 Mar 1; 10 (3): DOI:10.1097/HC9.0000000000000902
      PMID: PMC12922931
    • Journal Article
      Animal Naming Test Predicts Future Overt Hepatic Encephalopathy
      Bloom PP, Tapper EB, Asrani SK, Lok AS. Clinical Gastroenterology and Hepatology, 2026 Jan 1; DOI:10.1016/j.cgh.2025.11.031
      PMID: 41525864
    • Journal Article
      In memoriam: Professor Stephanos J. Hadziyannis
      Papatheodoridis GV, Lok ASF. Journal of Hepatology, 2026 Jan 10; DOI:10.1016/j.jhep.2025.12.002
    • Journal Article
      Protecting the future generation through science and HBV vaccination.
      Mak L-Y, Chan HL-Y, Yuen M-F, Heydtmann M, Ward JW, Suk-Fong Lok A, Gish RG, Global Consortium for Science-Led Hepatitis B Birth Dose Vaccine Policy . Hepatology, 2025 Dec 31; DOI:10.1097/HEP.0000000000001665
      PMID: 41474418
    • Journal Article
      AASLD ISDA Practice Guideline on treatment of chronic hepatitis B.
      Ghany MG, Pan CQ, Lok AS, Feld JJ, Lim JK, Wang SH, Kim AY, Tang AS, Nguyen MH, Naggie S, Sulkowski MS, Norberto R-B, Chen J, Murad MH, Mohammad KS, Terrault NA. Hepatology, 2025 Nov 4; DOI:10.1097/HEP.0000000000001549
      PMID: 41186418
    • Journal Article
      Recurrent Erythropoietic Protoporphyria Post Liver Transplant
      Robert A, Schechter S, Lok ASF. Clinical Gastroenterology and Hepatology, 2025 Nov 1; 23 (12): A27 - A28. DOI:10.1016/j.cgh.2025.02.019
      PMID: 40348106
    • Journal Article
      Reply: Enhancing automated speech analysis for hepatic encephalopathy detection
      Bloom PP, Lok AS. Hepatology, 2025 Jun 1; 81 (6): E155 DOI:10.1097/HEP.0000000000001151
      PMID: 39509361

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    Join us for the 27th Annual Liver Disease Wrap-Up conference taking place on Saturday, December 7, 2024