Anna Suk-Fong Lok, MD

Anna S. Lok
Dame Sheila Sherlock Distinguished University Professor of Hepatology and Internal Medicine
Alice Lohrman Andrews Research Professor of Hepatology
Professor of Internal Medicine
Assistant Dean for Clinical Research, Medical School
Office:
University of Michigan Medical School
Internal Medicine, Division of Gastroenterology and Hepatology
1500 East Medical Center Drive
Ann Arbor, MI 48109
Email:
[email protected]
Available to mentor
Anna Suk-Fong Lok, MD
Anna S. Lok
Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    Anna Suk-Fong Lok, M.D., is director of clinical hepatology and assistant dean for clinical research at the University of Michigan Medical School. She also is the Dame Sheila Sherlock Distinguished University Professor of Hepatology and Internal Medicine and Alice Lohrman Andrews Research Professor of Hepatology in the Department of Internal Medicine.

    In her role as assistant dean, Dr. Lok is responsible for leading, championing, and implementing recommendations from the Research Board of Directors to transform the clinical trials enterprise of the academic medical center. She is responsible for the overall leadership and direction, management, and oversight of the Clinical Trials Support Units and the Clinical Research Unit, training of clinical investigators, and facilitation and support of clinical research.

    Dr. Lok obtained her medical degree from the University of Hong Kong and her hepatology training under the late Dame Sheila Sherlock at the Royal Free Hospital in London, UK. She was on the faculty at the University of Hong Kong until she moved to the United States in 1992.

    Her research focuses on the natural history and treatment of hepatitis B and C, and the prevention of liver cancer. Her research is funded by the National Institutes of Health, federal and private foundations, and various pharmaceutical companies. She has published more than 600 papers on viral hepatitis and liver diseases and is the co-author of five editions of the American Association for the Study of Liver Diseases Association Guidelines on Hepatitis B. She was one of the top 1% most cited scientists in the world for the decade 2002-12. She has trained more than 60 fellows and junior faculty from all over the world, some of whom have risen to the ranks of full professors and directors of liver programs in their home country. She received a Distinguished Mentor Award from the Michigan Institute of Clinical and Health Research in 2012, an Inspirational Physician Award from the American Medical Association in 2014, and a Distinguished Mentor Award from the American Gastroenterological Association in 2022. She was inducted into the Clinical Excellence Society in the Department of Internal Medicine in 2013.

    Dr. Lok has received many awards throughout her career. She has been included in the list of “Best Doctors” and “Who's Who” for many years. She was inducted into the Association of American Physicians in 2012 and elected to the National Academy of Medicine in 2022. Recent awards include the Distinguished Scientist Award from the Hepatitis B Foundation in 2008, the Distinguished Women Scientist Award from the American Gastroenterological Association in 2008, the Distinguished Service Award from the American Association for the Study of Liver Diseases in 2011, the Distinguished Scientific Achievement Award from the American Liver Foundation in 2015, the William Beaumont Prize in Gastroenterology from the American Gastroenterological Association in 2016, a Gold Medal Award from the Canadian Association for the Study of the Liver and an honorary Doctor of Science degree from the University of Hong Kong in 2017, the International Recognition Award from the European Association of the Study of the Liver in 2018, and a Distinguished University Professorship from the University of Michigan in 2019.

    She is currently an associate editor of Hepatology Communication. She was an associate editor of HEPATOLOGY from 2001-06, a co-editor of the Journal of Viral Hepatitis from 2007-09, and a senior associate editor of GASTROENTEROLOGY from 2011-12.

    Dr. Lok was the President of the American Association for the Study of Liver Diseases in 2017.

    Qualifications

    • MD
      University of Hong Kong, Hong Kong, United Kingdom
      1990 - 1990
    • MB BS
      University of Hong Kong School of Medicine, Hong Kong, United Kingdom
      1972 - 1977

    Center Memberships

    • Center Member
      MM-PKUHSC Joint Institute
    • Center Member
      Center for Global Health Equity
    • Center Member
      Rogel Cancer Center
    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      Global REACH

    Research Overview

    Epidemiology, natural history, and treatment of hepatitis B and C
    Risk stratification of nonalcoholic fatty liver disease
    Prevention and early detection of hepatocellular carcinoma

    Recent Publications

    See All Publications
    • Journal Article
      A multivariate Bayesian biomarker screening algorithm that incorporates clinical covariates.
      Vinattieri MV, Panero F, Jin Q, Lok AS, Stingo FC, Tayob N. Stat Methods Med Res, 2026 Oct 21; 9622802261496428 DOI:10.1177/09622802261496428
      PMID: 42904922
    • Journal Article
      Animal Naming Test Predicts Future Overt Hepatic Encephalopathy
      Bloom PP, Tapper EB, Asrani SK, Lok AS. Clinical Gastroenterology and Hepatology, 2026 Oct 1; 24 (10): 2870 - 2871. DOI:10.1016/j.cgh.2025.11.031
      PMID: 41525864
    • Journal Article
      Critical role of hepatitis B birth dose vaccination in preventing mother-to-child transmission.
      Lok AS. Clin Infect Dis, 2026 Sep 24; DOI:10.1093/cid/ciag599
      PMID: 42781762
    • Journal Article
      Long-term outcomes after nucleos(t)ide analogue cessation in chronic hepatitis B – follow-up from the RETRACT-B cohort
      Dongelmans E, Hirode G, van Bӧmmel F, Jeng WJ, Chien RN, Chen CH, Kilany M, Su TH, Kao JH, Seto WK, Liang LY, Reikvam DH, Holmberg M, Furquim d'Almeida A, Papatheodoridi M, Maasoumy B, Hansen B, Post R, Pocurull A, Terrault N, Ghany M, Johannessen A, Lok A, Vanwolleghem T, Lens S, Cornberg M, Yuen MF, Wong G, Sonneveld M, Papatheodoridis G, Berg T, Hsu YC, Feld J, Janssen H. Journal of Hepatology, 2026 Jul 1; 85 (1): 61 - 70. DOI:10.1016/j.jhep.2026.03.030
      PMID: 41921700
    • Journal Article
      Associations between circulating immunologic markers and HCC in individuals with chronic HCV infection.
      Kale S, Argirion I, Oâ€Brien T, Hildesheim A, Liu Z, Pfeiffer R, Lok A, Morgan T, Lee M-H, Koshiol J. Journal of Clinical Oncology, 2026 May 30; 44 (16_suppl): e16271 - e16271. DOI:10.1200/jco.2026.44.16_suppl.e16271
    • Proceeding / Abstract / Poster
      745 A SELF-REPORTED BODY MAP: A PRACTICAL BEDSIDE TOOL FOR PHENOTYPING PAIN IN CHRONIC PANCREATITIS
      Machicado JD, Guevara-Lazo D, Troost J, Bay M, Harte S, Williams D, Lok A, Clauw D. Gastroenterology, 2026 May 7; 170 (6): s-2132-s-2133 DOI:10.1016/s0016-5085(26)05065-1
    • Proceeding / Abstract / Poster
      745 A SELF-REPORTED BODY MAP: A PRACTICAL BEDSIDE TOOL FOR PHENOTYPING PAIN IN CHRONIC PANCREATITIS
      Machicado JD, Guevara-Lazo D, Troost J, Bay M, Harte S, Williams D, Lok A, Clauw D. Gastrointestinal Endoscopy, 2026 May 6; 103 (5): s-2132-s-2133 DOI:10.1016/s0016-5107(26)04996-5
    • Journal Article
      In memoriam: Professor Stephanos J. Hadziyannis
      Papatheodoridis GV, Lok ASF. Journal of Hepatology, 2026 Jan 12; 84 (4): 683 - 685. DOI:10.1016/j.jhep.2025.12.002

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