Anna Suk-Fong Lok, MD
Internal Medicine, Division of Gastroenterology and Hepatology
1500 East Medical Center Drive
Ann Arbor, MI 48109
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About
Anna Suk-Fong Lok, M.D., is director of clinical hepatology and assistant dean for clinical research at the University of Michigan Medical School. She also is the Dame Sheila Sherlock Distinguished University Professor of Hepatology and Internal Medicine and Alice Lohrman Andrews Research Professor of Hepatology in the Department of Internal Medicine.
In her role as assistant dean, Dr. Lok is responsible for leading, championing, and implementing recommendations from the Research Board of Directors to transform the clinical trials enterprise of the academic medical center. She is responsible for the overall leadership and direction, management, and oversight of the Clinical Trials Support Units and the Clinical Research Unit, training of clinical investigators, and facilitation and support of clinical research.
Dr. Lok obtained her medical degree from the University of Hong Kong and her hepatology training under the late Dame Sheila Sherlock at the Royal Free Hospital in London, UK. She was on the faculty at the University of Hong Kong until she moved to the United States in 1992.
Her research focuses on the natural history and treatment of hepatitis B and C, and the prevention of liver cancer. Her research is funded by the National Institutes of Health, federal and private foundations, and various pharmaceutical companies. She has published more than 600 papers on viral hepatitis and liver diseases and is the co-author of five editions of the American Association for the Study of Liver Diseases Association Guidelines on Hepatitis B. She was one of the top 1% most cited scientists in the world for the decade 2002-12. She has trained more than 60 fellows and junior faculty from all over the world, some of whom have risen to the ranks of full professors and directors of liver programs in their home country. She received a Distinguished Mentor Award from the Michigan Institute of Clinical and Health Research in 2012, an Inspirational Physician Award from the American Medical Association in 2014, and a Distinguished Mentor Award from the American Gastroenterological Association in 2022. She was inducted into the Clinical Excellence Society in the Department of Internal Medicine in 2013.
Dr. Lok has received many awards throughout her career. She has been included in the list of “Best Doctors” and “Who's Who” for many years. She was inducted into the Association of American Physicians in 2012 and elected to the National Academy of Medicine in 2022. Recent awards include the Distinguished Scientist Award from the Hepatitis B Foundation in 2008, the Distinguished Women Scientist Award from the American Gastroenterological Association in 2008, the Distinguished Service Award from the American Association for the Study of Liver Diseases in 2011, the Distinguished Scientific Achievement Award from the American Liver Foundation in 2015, the William Beaumont Prize in Gastroenterology from the American Gastroenterological Association in 2016, a Gold Medal Award from the Canadian Association for the Study of the Liver and an honorary Doctor of Science degree from the University of Hong Kong in 2017, the International Recognition Award from the European Association of the Study of the Liver in 2018, and a Distinguished University Professorship from the University of Michigan in 2019.
She is currently an associate editor of Hepatology Communication. She was an associate editor of HEPATOLOGY from 2001-06, a co-editor of the Journal of Viral Hepatitis from 2007-09, and a senior associate editor of GASTROENTEROLOGY from 2011-12.
Dr. Lok was the President of the American Association for the Study of Liver Diseases in 2017.
Qualifications
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MDUniversity of Hong Kong, Hong Kong, United Kingdom
1990 - 1990
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MB BSUniversity of Hong Kong School of Medicine, Hong Kong, United Kingdom
1972 - 1977
Center Memberships
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Center MemberMM-PKUHSC Joint Institute
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Center MemberRogel Cancer Center
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Center MemberGlobal REACH
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Center MemberInstitute for Healthcare Policy and Innovation
Research Overview
Epidemiology, natural history, and treatment of hepatitis B and C
Risk stratification of nonalcoholic fatty liver disease
Prevention and early detection of hepatocellular carcinoma
Recent Publications
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Han Y, Shaw VR, Byun J, Thrift AP, Zhu C, Li D, Hatia RI, Kelley RK, Cleary SP, Lok AS, Bracci PM, Permuth JB, Bucur R, Knox J, Yuan JM, Singal AG, Jalal PK, Ghobrial RM, Kono Y, Shah DP, Nguyen MH, Parikh ND, Kim R, Wu HC, El-Serag H, Chang P, Chun YS, Gu J, Huff C, Rashid A, Hwang LY, Klein AP, Khaderi SA, Kaseb AO, McGlynn KA, Roberts LR, Hassan MM, Amos CI. International Journal of Cancer, 2026 Mar 1; 158 (5): 1193 - 1203.Journal ArticleLinkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits
DOI:10.1002/ijc.70136 PMID: 41013983 -
Singal AG, Jin Q, Marrero J, Parikh ND, Lok AS, Lopez C, Page-Lester S, Roberts LR, Reddy R, Luster M, Khaderi S, Asrani SK, El-Serag HB, Kanwal F, Feng Z, Tayob N. Hepatol Commun, 2026 Mar 1; 10 (3):Journal ArticleValidation of longitudinal biomarker screening algorithms for HCC detection in patients with cirrhosis.
DOI:10.1097/HC9.0000000000000902 PMID: PMC12922931 -
Bloom PP, Tapper EB, Asrani SK, Lok AS. Clinical Gastroenterology and Hepatology, 2026 Jan 1;Journal ArticleAnimal Naming Test Predicts Future Overt Hepatic Encephalopathy
DOI:10.1016/j.cgh.2025.11.031 PMID: 41525864 -
Papatheodoridis GV, Lok ASF. Journal of Hepatology, 2026 Jan 10;Journal ArticleIn memoriam: Professor Stephanos J. Hadziyannis
DOI:10.1016/j.jhep.2025.12.002 -
Mak L-Y, Chan HL-Y, Yuen M-F, Heydtmann M, Ward JW, Suk-Fong Lok A, Gish RG, Global Consortium for Science-Led Hepatitis B Birth Dose Vaccine Policy . Hepatology, 2025 Dec 31;Journal ArticleProtecting the future generation through science and HBV vaccination.
DOI:10.1097/HEP.0000000000001665 PMID: 41474418 -
Ghany MG, Pan CQ, Lok AS, Feld JJ, Lim JK, Wang SH, Kim AY, Tang AS, Nguyen MH, Naggie S, Sulkowski MS, Norberto R-B, Chen J, Murad MH, Mohammad KS, Terrault NA. Hepatology, 2025 Nov 4;Journal ArticleAASLD ISDA Practice Guideline on treatment of chronic hepatitis B.
DOI:10.1097/HEP.0000000000001549 PMID: 41186418 -
Robert A, Schechter S, Lok ASF. Clinical Gastroenterology and Hepatology, 2025 Nov 1; 23 (12): A27 - A28.Journal ArticleRecurrent Erythropoietic Protoporphyria Post Liver Transplant
DOI:10.1016/j.cgh.2025.02.019 PMID: 40348106 -
Bloom PP, Lok AS. Hepatology, 2025 Jun 1; 81 (6): E155Journal ArticleReply: Enhancing automated speech analysis for hepatic encephalopathy detection
DOI:10.1097/HEP.0000000000001151 PMID: 39509361
Featured News & Stories
Experts urge continued hepatitis B vaccine birth doses for newborns