Jillian N Pearring, PhD
Assistant Professor
Ophthalmology and Visual Sciences
1000 Wall Street
Ann Arbor, MI 48105
[email protected]

Available to mentor

Jillian N Pearring, PhD
Assistant Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Dr. Jillian N. Pearring is appointed as the Skillman Early Career Professor of Pediatric Ophthalmology Assistant Professor in the Department of Ophthalmology & Visual Science at the University of Michigan. She holds a joint appointment in the Department of Cell & Developmental Biology and is a member of the Center for Plasticity and Organ Design, Neuroscience Graduate Program, and Cell & Molecular Biology Graduate Program. Dr. Pearring started her first faculty appointment at U-M in 2017 following a postdoctoral fellowship at Duke University under the tutelage of Dr. Vadim Y. Arshavsky. Dr. Pearring's research program focuses on retinal photoreceptors, the sensory neurons detecting photons of light that enter the eye. Her lab studies neuronal differentiation, migration, and ciliation of photoreceptors during retinal development as well as the molecular and cellular processes used to form and maintain the light-sensitive outer segment organelle in mature photoreceptors. Ultimately, our research will provide a foundation to develop therapeutic strategies for patients suffering from inherited blindness. Complementary to her research program, Dr. Pearring is passionate about academic mentorship and DEI in STEM programs.

    Links
    Qualifications
    • EBMO Practical Course on High-Accuracy CLEM at Cryo and Room Temperature
      EMBL Laboratories, Heidelberg, 2019
    • 4-Day EMBO Lab Leadership Training Course
      University of Michigan, United States, 2018
    • Postdoctoral Fellow
      Duke University, Ophthalmology, 2017
    • Postdoctoral Career Development Workshop
      ASCB MAC, United States, 2016
    • Experimental Tools in Model Systems of Translational Vision Research
      Jackson Labs, United States, 2006
    • PhD
      University of Louisville, Abell Administration Building 323 East Chestnut Street, 2010
    • BA
      Boston University, Boston, 2004
    Center Memberships
    • Center Member
      Center for Cell Plasticity and Organ Design
    Research Overview

    - My research program centers on retinal photoreceptors, the sensory neurons (i.e. rods and cones) detecting
    photons of light that enter the eye. We study neuronal differentiation, migration, and ciliation of rod photoreceptors
    during retinal development as well as the molecular and cellular processes used to form and maintain the lightsensitive
    outer segment organelle of mature photoreceptors. Photoreceptor cell death is a hallmark of many
    inherited retinal degenerations in humans and often the underlying genetic defect is associated with ciliary or
    photoreceptor-specific proteins. We aim to uncover important cellular processes in photoreceptors and how these
    processes go wrong during disease.

    Recent Publications See All Publications
    • Presentation
      Mouse Model of Retinitis Pigmentosa 2 has a Photoreceptor Nuclear Migration Defect.
      Pearring J. 2024 Oct;
    • Presentation
      The tectonic complex impedes membrane diffusion through the photoreceptor connecting cilium.
      Pearring J. 2024 Sep;
    • Presentation
      The tectonic complex impedes membrane diffusion through the photoreceptor connecting cilium.
      Pearring J. 2024 Aug;
    • Presentation
      The tectonic complex impedes membrane diffusion through the photoreceptor connecting cilium.
      Pearring J. 2024 Jun;
    • Presentation
      The science of sight: how photoreceptors cells capture light.
      Pearring J. 2024 Mar;
    • Presentation
      Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration.
      Pearring J. 2024 Jan;
    • Journal Article
      The tectonic complex regulates membrane protein composition in the photoreceptor cilium.
      Truong HM, Cruz-Colón KO, Martínez-Márquez JY, Willer JR, Travis AM, Biswas SK, Lo W-K, Bolz HJ, Pearring JN. Nat Commun, 2023 Sep 13; 14 (1): 5671 DOI:10.1038/s41467-023-41450-z
      PMID: 37704658
    • Presentation
      The tectonic complex impedes membrane diffusion through the photoreceptor connecting cilium.
      Pearring J. 2023 Jun;
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