1000 Wall Street
Ann Arbor, MI 48105
Available to mentor
Dr. Jillian N. Pearring is appointed as the Skillman Early Career Professor of Pediatric Ophthalmology Assistant Professor in the Department of Ophthalmology & Visual Science at the University of Michigan. She holds a joint appointment in the Department of Cell & Developmental Biology and is a member of the Center for Plasticity and Organ Design, Neuroscience Graduate Program, and Cell & Molecular Biology Graduate Program. Dr. Pearring started her first faculty appointment at U-M in 2017 following a postdoctoral fellowship at Duke University under the tutelage of Dr. Vadim Y. Arshavsky. Dr. Pearring's research program focuses on retinal photoreceptors, the sensory neurons detecting photons of light that enter the eye. Her lab studies neuronal differentiation, migration, and ciliation of photoreceptors during retinal development as well as the molecular and cellular processes used to form and maintain the light-sensitive outer segment organelle in mature photoreceptors. Ultimately, our research will provide a foundation to develop therapeutic strategies for patients suffering from inherited blindness. Complementary to her research program, Dr. Pearring is passionate about academic mentorship and DEI in STEM programs.
-
EBMO Practical Course on High-Accuracy CLEM at Cryo and Room TemperatureEMBL Laboratories, Heidelberg, 2019
-
4-Day EMBO Lab Leadership Training CourseUniversity of Michigan, United States, 2018
-
Postdoctoral FellowDuke University, Ophthalmology, 2017
-
Postdoctoral Career Development WorkshopASCB MAC, United States, 2016
-
Experimental Tools in Model Systems of Translational Vision ResearchJackson Labs, United States, 2006
-
PhDUniversity of Louisville, Abell Administration Building 323 East Chestnut Street, 2010
-
BABoston University, Boston, 2004
-
Center MemberCenter for Cell Plasticity and Organ Design
- My research program centers on retinal photoreceptors, the sensory neurons (i.e. rods and cones) detecting
photons of light that enter the eye. We study neuronal differentiation, migration, and ciliation of rod photoreceptors
during retinal development as well as the molecular and cellular processes used to form and maintain the lightsensitive
outer segment organelle of mature photoreceptors. Photoreceptor cell death is a hallmark of many
inherited retinal degenerations in humans and often the underlying genetic defect is associated with ciliary or
photoreceptor-specific proteins. We aim to uncover important cellular processes in photoreceptors and how these
processes go wrong during disease.
-
Pearring J. 2024 Oct;PresentationMouse Model of Retinitis Pigmentosa 2 has a Photoreceptor Nuclear Migration Defect.
-
Pearring J. 2024 Sep;PresentationThe tectonic complex impedes membrane diffusion through the photoreceptor connecting cilium.
-
Pearring J. 2024 Aug;PresentationThe tectonic complex impedes membrane diffusion through the photoreceptor connecting cilium.
-
Pearring J. 2024 Jun;PresentationThe tectonic complex impedes membrane diffusion through the photoreceptor connecting cilium.
-
Pearring J. 2024 Mar;PresentationThe science of sight: how photoreceptors cells capture light.
-
Pearring J. 2024 Jan;PresentationDisrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration.
-
Truong HM, Cruz-Colón KO, Martínez-Márquez JY, Willer JR, Travis AM, Biswas SK, Lo W-K, Bolz HJ, Pearring JN. Nat Commun, 2023 Sep 13; 14 (1): 5671Journal ArticleThe tectonic complex regulates membrane protein composition in the photoreceptor cilium.
DOI:10.1038/s41467-023-41450-z PMID: 37704658 -
Pearring J. 2023 Jun;PresentationThe tectonic complex impedes membrane diffusion through the photoreceptor connecting cilium.