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7433 Medical Science Building I, 1150 West Medical Center Drive
Ann Arbor, Michigan 48109-0615
Available to mentor
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Postdoctoral FellowUniversity of Michigan Medical School, Anesthesiology, 2009
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Residency in Critical Care MedicineSchool of Medicine, Universidad de la República, Montevideo, 2005
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MDSchool of Medicine, Universidad de la República, Montevideo, 2000
- Regulation of Arousal States and Neural Correlates of Consciousness.- Research in my laboratory focuses on the neural mechanisms underlying the generation of arousal states of sleep and wakefulness, as well as the neural regulation of the loss and resumption of consciousness with respect to general anesthesia.
- Sleep and Pain Interactions.- Ongoing studies in my lab aim to understand the brain circuitry by which sleep disruption increases pain and paves the way for chronic pain.
- Mechanisms of Hypothermia.- We study the neural underpinnings of hypothermia during sleep and hypometabolic states (torpor), and their potential implications in neuroprotection.
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Wasilczuk AZ, Rinehart C, Aggarwal A, Stone ME, Mashour GA, Avidan MS, Kelz MB, Proekt A, ReCCognition Study Group . Proc Natl Acad Sci U S A, 2024 Jan 16; 121 (3): e2312913120Journal ArticleHormonal basis of sex differences in anesthetic sensitivity.
DOI:10.1073/pnas.2312913120 PMID: 38190526 -
Kolbman N, Liu T, Guzzo P, Gilligan J, Mashour GA, Vanini G, Pal D. Curr Biol, 2023 Dec 18; 33 (24): R1282 - R1283.Journal ArticleIntravenous psilocybin attenuates mechanical hypersensitivity in a rat model of chronic pain.
DOI:10.1016/j.cub.2023.10.016 PMID: 38113836 -
Vanini G. Curr Biol, 2023 Apr 24; 33 (8): R316 - R318.Journal ArticleNarcolepsy: Mending a broken neural circuit that controls arousal.
DOI:10.1016/j.cub.2023.02.053 PMID: 37098337 -
Labonte AK, Kafashan M, Huels ER, Blain-Moraes S, Basner M, Kelz MB, Mashour GA, Avidan MS, Palanca BJA, ReCCognition Study Group . Br J Anaesth, 2023 Feb; 130 (2): e233 - e242.Journal ArticleThe posterior dominant rhythm: an electroencephalographic biomarker for cognitive recovery after general anaesthesia.
DOI:10.1016/j.bja.2022.01.019 PMID: 35183346 -
2022 Dec 1;PresentationZooming into preoptic glutamatergic mechanisms controlling arousal, anesthesia and cortical dynamics
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2022 Oct 1;PresentationPanel Presentation: Snap-Talk in the Fundamentals of Anesthesiology Track
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2022 Jun 1;PresentationPanel Presentation: Preoptic Glutamatergic Neurons Promote Wakefulness, Suppress REM Sleep, and Reduce Body Temperature - The Preoptic Area in Sleep and Arousal
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2022 Apr 1;PresentationPlenary Presentaion: Preoptic Hypothalamic Mechanisms Controlling Sleep-Wake States Do Not Influence the Loss and Recovery of Consciousness Associated with Isoflurane Anesthesia