Tom K Kerppola
Professor of Biological Chemistry
Professor of Biophysics
[email protected]

Available to mentor

Tom K Kerppola
  • About
  • Center Memberships
  • Recent Publications
  • About

    My laboratory investigates the mechanisms whereby transcription factor complexes regulate gene expression

    Center Memberships
    • Center Member
      Center for Cell Plasticity and Organ Design
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    • Center Member
      Caswell Diabetes Institute
    Recent Publications See All Publications
    • Journal Article
      Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFκB p50 recruitment.
      Burns VE, Kerppola TK. Immunology, 2022 Sep; 167 (1): 105 - 121. DOI:10.1111/imm.13527
      PMID: 35751391
    • Journal Article
      Virus Infection Induces Keap1 Binding to Cytokine Genes, Which Recruits NF-κB p50 and G9a-GLP and Represses Cytokine Transcription.
      Burns VE, Kerppola TK. J Immunol, 2021 Sep 1; 207 (5): 1437 - 1447. DOI:10.4049/jimmunol.2100355
      PMID: 34400522
    • Journal Article
      ATR-101 inhibits cholesterol efflux and cortisol secretion by ATP-binding cassette transporters, causing cytotoxic cholesterol accumulation in adrenocortical carcinoma cells.
      Burns VE, Kerppola TK. Br J Pharmacol, 2017 Oct; 174 (19): 3315 - 3332. DOI:10.1111/bph.13951
      PMID: 28710789
    • Journal Article
      Visualization of the Genomic Loci That Are Bound by Specific Multiprotein Complexes by Bimolecular Fluorescence Complementation Analysis on Drosophila Polytene Chromosomes.
      Deng H, Kerppola TK. Methods Enzymol, 2017 589: 429 - 455. DOI:10.1016/bs.mie.2017.02.003
      PMID: 28336073
    • Journal Article
      ATR-101 disrupts mitochondrial functions in adrenocortical carcinoma cells and in vivo.
      Cheng Y, Kerppola RE, Kerppola TK. Endocr Relat Cancer, 2016 Apr; 23 (4): 1 - 19. DOI:10.1530/ERC-15-0527
      PMID: 26843528
    • Journal Article
      KAP1 represses differentiation-inducible genes in embryonic stem cells through cooperative binding with PRC1 and derepresses pluripotency-associated genes.
      Cheng B, Ren X, Kerppola TK. Mol Cell Biol, 2014 Jun; 34 (11): 2075 - 2091. DOI:10.1128/MCB.01729-13
      PMID: 24687849
    • Journal Article
      Visualization of the Drosophila dKeap1-CncC interaction on chromatin illumines cooperative, xenobiotic-specific gene activation.
      Deng H, Kerppola TK. Development, 2014 Aug; 141 (16): 3277 - 3288. DOI:10.1242/dev.110528
      PMID: 25063457
    • Journal Article
      Regulation of Drosophila metamorphosis by xenobiotic response regulators.
      Deng H, Kerppola TK. PLoS Genet, 2013 9 (2): e1003263 DOI:10.1371/journal.pgen.1003263
      PMID: 23408904