Steven E Harte, PhD
Ann Arbor, MI 48105
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About
Dr. Steven Harte
Associate Professor of Anesthesiology and Internal Medicine
Associate Director, Chronic Pain and Fatigue Research Center
Dr. Harte is a pain neuroscientist at the University of Michigan Medical School with over 25 years of experience advancing the understanding and treatment of chronic pain through innovative research and education. His NIH-funded research program employs a multidisciplinary approach—integrating preclinical models, psychophysics, inflammatory biomarkers, patient-reported outcomes, wearable technology, and functional brain imaging—to investigate chronic pain mechanisms and develop novel analgesic treatments. His specialized research interests include multisensory amplification and neural integration, neural-immune interface in chronic pain, endo-/cannabinoid and psychedelic analgesics, influence of built and natural environments on pain perception, pain affect, and mechanisms of pain modulation.
Dr. Harte has contributed to several major national pain research initiatives, including the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network, the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN), the HEAL BACPAC and BEST initiatives, and the AURORA Study on trauma, where he led multi-site quantitative sensory testing development. At the University of Michigan, he holds faculty affiliations with the Neuroscience Graduate Program, Michigan Neuroscience Institute, Opioid Research Institute, Sensory Science Initiative, and Michigan Psychedelic Center (M-PsyC). He serves as Director of the Postdoctoral T32 in Translational Science at the Michigan Institute for Clinical and Health Research (MICHR) and Co-Director of the HEAL National K12 Clinical Pain Career Development Program.
Committed to translating research into practical solutions, Dr. Harte co-founded Arbor Medical Innovations, where he serves as Chief Scientific Officer. His work in developing novel medical devices, research technologies, and eHealth applications has resulted in multiple patents related to pain measurement and wearable technology, furthering his mission to improve the lives of individuals suffering from chronic pain.
Links
Chronic Pain and Fatigue Research Center Department of Anesthesiology Neuroscience Graduate Program HEAL National K12 Michigan Institute of Clinical and Health Research Opioid Research Institute Michigan Psychedelic Center (M-PsyC) Arbor Medical Innovations
Center Memberships
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Center MemberOpioid Research Institute
Research Overview
- Quantitative sensory testing and multisensory sensitivity
- Preclinical pain assessment
- Functional and chemical neuroimaging
- Neuropsychopharmacology
- Neural-Immune interactions
- Consciousness neuroscience
- Cannabinoids/Endocannabinoids
- Environmental influences on pain
- Biomedical technology development
Recent Publications
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Frey-Law LA, Berardi G, Ansari B, Liu Y, Satpathy-Horton B, Sluka KA, Vance CG, Dailey DL, McCarthy RJ, Wager TD, Lindquist MA, Harte SE. 2026 Aug 19; medRxiv,PreprintPain and Pain Sensitivity Assessments in the Acute to Chronic Pain Signatures (A2CPS) Program
DOI:10.64898/2026.08.14.26360457 -
Mellen EJ, Poplin T, Jovanovic T, Rowland GE, House SL, Beaudoin FL, An X, Stevens JS, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Hudak LA, Pascual JL, Seamon MJ, Pearson C, Peak DA, Domeier RM, Rathlev NK, O'Neil BJ, Sanchez LD, Bruce SE, Harte SE, Kessler RC, Koenen KC, McLean SA, Harnett NG, Ressler KJ. JAMA Psychiatry, 2026 Jul 29;Journal ArticlePrior Sexual Violence, PTSD Symptoms, and Recovery Trajectories After New Trauma.
DOI:10.1001/jamapsychiatry.2026.2219 PMID: PMC13420162 -
Hidalgo-Lopez E, Portengen CM, Smith T, Angstadt M, Schrepf A, Clauw DJ, Harte SE, Heitzeg MM, Mindell JA, Beltz AM, Kaplan CM. Communications Biology, 2026 Jul 23;Journal ArticleSex-specific developmental pathways link brain networks, sensory sensitivity, and sleep to adolescent pain
DOI:10.1038/s42003-026-10619-9 -
Webb EK, Jajoo A, Balakundi V, Sendi MSE, Koenen KC, Linnstaedt SD, House SL, An X, Stevens JS, Neylan TC, Clifford GD, Jovanovic T, Germine LT, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Pearson C, Merchant RC, Domeier RM, Rathlev NK, O’Neil BJ, Sergot P, Sanchez LD, Bruce SE, Harte SE, Kessler RC, McLean SA, Ressler KJ, Daskalakis NP, Harnett NG. 2026 Jul 22; medRxiv,PreprintAncestry-Calibrated Polygenic Risk Scores Predict PTSD Trajectories in Recent Trauma Survivors and Interact with Neighborhood Resources
DOI:10.64898/2026.07.17.26358149 -
Kim HH, Kumar A, Nishimi K, Tiemeier H, Smoller JW, House SL, Beaudoin FL, An X, Stevens JS, Neylan TC, Clifford GD, Linnstaedt SD, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Punches BE, Swor RA, Pascual JL, Seamon MJ, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Bruce SE, Harte SE, Ressler KJ, McLean SA, Koenen KC, Choi KW. Psychol Trauma, 2026 Jun 25;Journal ArticleMultidimensional resiliency factors and psychopathology after acute trauma: Results from a prospective cohort study.
DOI:10.1037/tra0002183 PMID: 42347781 -
Santos JL, van Rooij SJ, House SL, Beaudoin FL, An X, Neylan TC, Clifford GD, Jovanovic T, Linnstaedt SD, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Hudak LA, Pascual JL, Seamon MJ, Harris E, Pearson C, Peak DA, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Bruce SE, Harte SE, Kessler RC, Koenen KC, Ressler KJ, McLean SA, Stevens JS. Journal of Mood and Anxiety Disorders, 2026 Jun 1; 14:Journal ArticleSocial support and post-traumatic stress symptoms: Longitudinal bidirectional relationships in the AURORA study
DOI:10.1016/j.xjmad.2026.100180 -
McKibben LA, Layne MN, Albertorio-Sáez LM, Zhao Y, Branham EM, House SL, Beaudoin FL, An X, Stevens JS, Neylan TC, Clifford GD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O'Neil BJ, Sanchez LD, Bruce SE, Sheridan JF, Harte SE, Kessler RC, Koenen KC, Ressler KJ, McLean SA, Linnstaedt SD. J Pain, 2026 May 28; 106326Journal ArticlePeritraumatic C-reactive protein levels predict pain outcomes following traumatic stress exposure in a sex-dependent manner.
DOI:10.1016/j.jpain.2026.106326 PMID: 42214575 -
Schrepf A, Smith T, Waller N, Harris RE, Ichesco E, Kaplan CM, Till SR, Williams DA, As-Sanie S, Evanski JM, Urquhart A, Brummett CM, Clauw DJ, Harte SE. 2026 May 27;PreprintGeneralized Sensory Sensitivity for Prediction of Post-Surgical Analgesic Outcomes: An Observational Cohort Study of Total Hip Arthroplasty and Hysterectomy.
DOI:10.64898/2026.05.26.26354108 PMID: 42245048
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