Maude T Lane Professor of Surgical Immunology
Professor of Surgery
Professor of Cell and Developmental Biology
[email protected]
Available to mentor
Marina Pasca Di Magliano
Professor
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Embryonic signaling pathways in pancreatic cancerUniversity of California, San Francisco, San Francisco, 2008
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberCenter for Cell Plasticity and Organ Design
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Center MemberRogel Cancer Center
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Lee KE, Pasca di Magliano M. Cancer Immunol Res, 2024 Jul 11; OF1 - OF2.Journal ArticleUnveiling the Culprit: IL17 Signaling in the Pancreatic Epithelium Drives Tumorigenesis.
DOI:10.1158/2326-6066.CIR-24-0479 PMID: 38990149 -
Donahue KL, Watkoske HR, Kadiyala P, Du W, Brown K, Scales MK, Elhossiny AM, Espinoza CE, Lasse Opsahl EL, Griffith BD, Wen Y, Sun L, Velez-Delgado A, Renollet NM, Morales J, Nedzesky NM, Baliira RK, Menjivar RE, Medina-Cabrera PI, Rao A, Allen B, Shi J, Frankel TL, Carpenter ES, Bednar F, Zhang Y, Pasca di Magliano M. Cancer Discov, 2024 Jul 3;Journal ArticleOncogenic KRAS-dependent stromal interleukin-33 directs the pancreatic microenvironment to promote tumor growth.
DOI:10.1158/2159-8290.CD-24-0100 PMID: 38958646 -
Sigafoos AN, Tolosa EJ, Carr RM, Fernandez-Barrena MG, Almada LL, Pease DR, Hogenson TL, Raja Arul GL, Mousavi F, Sen S, Vera RE, Marks DL, Flores LF, LaRue-Nolan KC, Wu C, Bamlet WR, Vrabel AM, Sicotte H, Schenk EL, Smyrk TC, Zhang L, Rabe KG, Oberg AL, Zaphiropoulos PG, Chevet E, Graham RP, Hagen CE, di Magliano MP, Elsawa SF, Pin CL, Mao J, McWilliams RR, Fernandez-Zapico ME. Cancer Res Commun, 2024 Jul 1; 4 (7): 1677 - 1689.Journal ArticleKRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis.
DOI:10.1158/2767-9764.CRC-23-0464 PMID: 38896052 -
Carpenter ES, Kadiyala P, Elhossiny AM, Kemp SB, Li J, Steele NG, Nicolle R, Nwosu ZC, Freeman J, Dai H, Paglia D, Du W, Donahue K, Morales J, Medina-Cabrera PI, Bonilla ME, Harris L, The S, Gunchick V, Peterson N, Brown K, Mattea M, Espinoza CE, McGue J, Kabala SM, Baliira RK, Renollet NM, Mooney AG, Liu J, Bhalla S, Farida JP, Ko C, Machicado JD, Kwon RS, Wamsteker E-J, Schulman A, Anderson MA, Law R, Prabhu A, Coulombe PA, Rao A, Frankel TL, Bednar F, Shi J, Sahai V, Pasca Di Magliano M. Clin Cancer Res, 2024 Jun 3; 30 (11): 2497 - 2513.Journal ArticleKRT17high/CXCL8+ Tumor Cells Display Both Classical and Basal Features and Regulate Myeloid Infiltration in the Pancreatic Cancer Microenvironment.
DOI:10.1158/1078-0432.CCR-23-1421 PMID: 37851080 -
Tinsley SL, Shelley RA, Mall GK, Chianis ERD, Dhiman A, Baral G, Kothandaraman H, Thoma MC, Daniel CJ, Lanman NA, di Magliano MP, Narla G, Solorio L, Dykhuizen EC, Sears RC, Allen-Petersen BL. 2024 May 23;PreprintKRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development.
DOI:10.1101/2023.07.01.547283 PMID: 38826439 -
Barravecchia I, Lee JM, Manassa J, Magnuson B, Ferris SF, Cavanaugh S, Steele NG, Espinoza CE, Galban CJ, Ramnath N, Frankel TL, Pasca di Magliano M, Galban S. 2024 Mar 1;Additional ScholarshipData from Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice
DOI:10.1158/1541-7786.c.7100174.v1 -
Barravecchia I, Lee JM, Manassa J, Magnuson B, Ferris SF, Cavanaugh S, Steele NG, Espinoza CE, Galban CJ, Ramnath N, Frankel TL, Pasca di Magliano M, Galban S. 2024 Mar 1;Additional ScholarshipData from Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice
DOI:10.1158/1541-7786.c.7100174 -
Barravecchia I, Lee JM, Manassa J, Magnuson B, Ferris SF, Cavanaugh S, Steele NG, Espinoza CE, Galban CJ, Ramnath N, Frankel TL, Pasca di Magliano M, Galban S. 2024 Mar 1;Additional ScholarshipSupplemental Figure S1 from Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice
DOI:10.1158/1541-7786.25325096
Department News
A research partnership between Michigan Medicine and Gift of Life Michigan has revealed a new pathway to understanding the progression of pancreatic cancer.
Department News
Marina has been inducted as a 2022 Fellow of the American Association for the Advancement of Science (AAAS).