Maud T Lane Professor of Surgical Immunology
Professor of Surgery
Professor of Cell and Developmental Biology and Co-Director of Pancreatic Cancer Laboratory
Rogel Cancer Center
[email protected]
Available to mentor
Marina Pasca di Magliano, PhD
Professor
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Embryonic signaling pathways in pancreatic cancerUniversity of California, San Francisco, San Francisco, 2008
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberCenter for Cell Plasticity and Organ Design
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Center MemberRogel Cancer Center
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Nwosu ZC, Giza H, Nassif M, Charlestin V, Menjivar RE, Kim D, Kemp SB, Sajjakulnukit P, Andren A, Zhang L, Lai WK, Loveless I, Steele NG, Hu J, Hu B, Wang S, Pasca di Magliano M, Lyssiotis CA. JCI Insight, 2025 Jan 7;Journal ArticleMulti-dimensional analyses identify genes of high priority for pancreatic cancer research.
DOI:10.1172/jci.insight.174264 PMID: 39774001 -
Tinsley SL, Chianis ERD, Shelley RA, Mall GK, Dhiman A, Baral G, Kothandaraman H, Thoma MC, English IA, Daniel CJ, Acosta LCS, Solorio L, Atallah Lanman N, Pasca di Magliano M, Narla G, Dykhuizen EC, Sears RC, Allen-Petersen BL. Oncogene, 2024 Dec; 43 (50): 3673 - 3687.Journal ArticleKRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development.
DOI:10.1038/s41388-024-03196-w PMID: 39443726 -
Carpenter ES, Vendramini-Costa DB, Hasselluhn MC, Maitra A, Olive KP, Cukierman E, Pasca di Magliano M, Sherman MH. Cancer Res, 2024 Nov 4; 84 (21): 3505 - 3508.Journal ArticlePancreatic Cancer-Associated Fibroblasts: Where Do We Go from Here?
DOI:10.1158/0008-5472.CAN-24-2860 PMID: 39283867 -
Hinshaw R, Espinoza C, Zhang Y, Pasca di Magliano M, Galban S. Cancer Immunology Research, 2024 Oct 18; 12 (10_Supplement): b019 - b019.Journal ArticleAbstract B019: Investigating the role of antigen-presenting fibroblasts in the tumor microenvironment of non-small cell lung cancer
DOI:10.1158/2326-6074.tumimm24-b019 -
Donahue KL, Watkoske HR, Kadiyala P, Du W, Brown K, Scales MK, Elhossiny AM, Espinoza CE, Lasse Opsahl EL, Griffith BD, Wen Y, Sun L, Velez-Delgado A, Renollet NM, Morales J, Nedzesky NM, Baliira RK, Menjivar RE, Medina-Cabrera PI, Rao A, Allen B, Shi J, Frankel TL, Carpenter ES, Bednar F, Zhang Y, Pasca di Magliano M. Cancer Discov, 2024 Oct 4; 14 (10): 1964 - 1989.Journal ArticleOncogenic KRAS-Dependent Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor Growth.
DOI:10.1158/2159-8290.CD-24-0100 PMID: 38958646 -
Bonilla ME, Radyk MD, Perricone MD, Elhossiny AM, Harold AC, Medina-Cabrera PI, Kadiyala P, Shi J, Frankel TL, Carpenter ES, Green MD, Mitrea C, Lyssiotis CA, Pasca di Magliano M. JCI Insight, 2024 Aug 13; 9 (18):Journal ArticleMetabolic landscape of the healthy pancreas and pancreatic tumor microenvironment.
DOI:10.1172/jci.insight.180114 PMID: 39315547 -
Hannifin S, Mello AM, Ngodup T, Donahue KL, Pasca di Magliano M, Lee KE. Cancer Research, 2024 Sep 15; 84 (17_Supplement_2): a038 - a038.Journal ArticleAbstract A038: The hypoxic regulation of macrophage function in pancreatic cancer
DOI:10.1158/1538-7445.pancreatic24-a038 -
Elhossiny AM, Okoye J, Williams I, Zhang Y, Watkoske H, Deshpande A, Fertig E, Rao A, Carpenter ES, Frankel TL, Pasca di Magliano M. Cancer Research, 2024 Sep 15; 84 (17_Supplement_2): a046 - a046.Proceeding / Abstract / PosterAbstract A046: Spatial transcriptomics reveals heterogeneity of epithelial and stromal compartments in healthy and tumor pancreas
DOI:10.1158/1538-7445.pancreatic24-a046
Department News
A research partnership between Michigan Medicine and Gift of Life Michigan has revealed a new pathway to understanding the progression of pancreatic cancer.
Department News
Marina has been inducted as a 2022 Fellow of the American Association for the Advancement of Science (AAAS).
