Rodica Busui
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About
Rodica Pop-Busui, MD, PhD, is the Larry D. Soderquist Professor of Diabetes, a prominent diabetologist at Michigan Medicine and a recognized leader in the field of diabetes and diabetes complications. She is the Vice Chair for Clinical Research in the Department of Internal Medicine and the Associate Director of Clinical Research, Mentoring and Development of the Elizabeth Caswell Diabetes Institute at the University of Michigan. Her research interests involve chronic complications of diabetes, particularly diabetic peripheral and cardiovascular autonomic neuropathy, as well as diabetic foot complications, diabetic kidney disease and cardiovascular disease, and the design and conduct of traditional and pragmatic clinical trials for patients with diabetes.
Dr. Pop-Busui has published more than 200 peer-reviewed manuscripts and book chapters, and received awards from the American Diabetes Association (ADA) and the University of Michigan. She has chaired the 2017 American Diabetes Association Position Statement on Diabetic Neuropathy, and has served as Chair of the American Diabetes Association Scientific Research Review Clinical and Chair of the ADA Diabetes & Cardiovascular Disease Interest Group. Most recently she has been elected to chair the Precision Prognostic in Type 1 Diabetes Working Group of the American Diabetes Association/European Association for the Study of Diabetes.
She has been PI/CoI and member of the Steering Committee in several landmark diabetes clinical trials including: the NHLBI-funded Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, the NIDDK funded Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications, Preventing Early Renal Loss in Type 1 Diabetes (PERL), Bypass Angioplasty Revascularization Diabetes 2 (BARI- 2D) and Glycemia Reduction Approaches in Type 2 Diabetes-A Comparative Effectiveness Study (GRADE) . In addition, she designed and leads several investigator-initiated studies funded by NIDDK and Pharma to unveil disease modifying agents for diabetic neuropathy and other chronic diabetes complications.
Dr Pop-Busui is the corresponding principal investigator and member of the Steering Committee of the recently established NIDDK Diabetes Foot Consortium and one of the principal investigators of the JDRF Center of Excellence at the University of Michigan .
Dr Pop-Busui had also mentored junior physician scientists and other trainees in their career developments, has implemented and directs the Clinical Trials Academy at the University of Michigan, and is the PI on the Steno North American Fellowship funded by Novo Nordisk Foundation to foster new collaborations and mentoring between physicians scientists from the University of Michigan and the 5 Steno Diabetes Centers in Denmark.
Qualifications
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PhDUniversity of Timisoara, School of Medicine, Timisoara, Romania
1995 - 2001
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MDUniversity of Timisoara, School of Medicine, Timisoara, Romania
1981 - 1987
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BSCollege of Mathematics-Physics, Resita, Romania
1976 - 1981
Center Memberships
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Center MemberGlobal REACH
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Center MemberMM-PKUHSC Joint Institute
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Center MemberInstitute for Healthcare Policy and Innovation
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Center MemberCaswell Diabetes Institute
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center MemberCenter for Global Health Equity
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Center MemberAI and Digital Health Innovation
Research Overview
Dr. Pop-Busui has concentrated her scholarship and research efforts on translational and clinical research focused in understanding the mechanisms of diabetic complications, particularly of diabetic peripheral neuropathy and cardiovascular autonomic neuropathy, and to understand their role in the development of the high cardiovascular risk complicating diabetes. As a result of her efforts, her research has been funded by the National Institute of Health/National Heart, Lung and Blood Institute, the American Diabetes Association, the Juvenile Diabetes Research Foundation, other foundations and industry. She also is and has been a PI or co-PI on several landmark diabetes trials funded by the National Institute of Health, such as the NHLBI-funded Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, the NHLBI-funded Bypass Angioplasty Revascularization Investigation Type 2 Diabetes (BARI 2D) study, and the NIDDK-funded Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC).
Recent Publications
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Levine D, Briceno E, Gross A, Whitney R, YE W, Busui R, Hsu W-L, Giordani B, Ferber R, Marshall L, Aparicio H, Beiser A, Gutierrez J, Rundek T, Rooney M, Shikany J, Li J, Allen N, Hughes T, Power M, Gerstein H, Lopez O, Mukamal K, Selvin E, Yaffe K, Hayward R. Stroke, 2026 Jan 31; 57 (Suppl_1):Proceeding / Abstract / PosterAbstract DP183: Association between Cumulative Fasting Blood Glucose and Later-life Cognitive Decline
DOI:10.1161/str.57.suppl_1.dp183 -
Amighi A, ghormli LE, Braffett B, Holt S, Bebu I, Trapani V, Martin C, Busui R, Sarma A, Wessells H. Journal of Urology, 2025 Apr 10; 213 (5S): e1344Proceeding / Abstract / PosterPD38-01 CARDIOVASCULAR AUTONOMIC NEUROPATHY AND LONGITUDINAL ASSOCIATION WITH ERECTILE DYSFUNCTION IN MEN WITH TYPE 1 DIABETES: UROEDIC STUDY
DOI:10.1097/01.ju.0001110192.16065.99.01 -
Ismail A, Shadid H, Huang Y, Hutten C, Vasbinder A, Pizzo I, Catalan T, Machado K, Blakely P, Banerjee M, Rubenfire M, Williams G, Busui R, Hayek S. Circulation, 2024 Nov 16; 150 (Suppl_1): a4143186 - a4143186.Journal ArticleAbstract 4143186: Prior Statin Therapy Reduces Inflammation and Improves Outcomes in Patients Hospitalized for Covid-19: A Prospective Multicenter Cohort Study
DOI:10.1161/circ.150.suppl_1.4143186 -
Phillip M, Achenbach P, Addala A, Albanese-O'Neill A, Battelino T, Bell KJ, Besser REJ, Bonifacio E, Colhoun HM, Couper JJ, Craig ME, Danne T, de Beaufort C, Dovc K, Driscoll KA, Dutta S, Ebekozien O, Elding Larsson H, Feiten DJ, Frohnert BI, Gabbay RA, Gallagher MP, Greenbaum CJ, Griffin KJ, Hagopian W, Haller MJ, Hendrieckx C, Hendriks E, Holt RIG, Hughes L, Ismail HM, Jacobsen LM, Johnson SB, Kolb LE, Kordonouri O, Lange K, Lash RW, Lernmark Å, Libman I, Lundgren M, Maahs DM, Marcovecchio ML, Mathieu C, Miller KM, O'Donnell HK, Oron T, Patil SP, Pop-Busui R, Rewers MJ, Rich SS, Schatz DA, Schulman-Rosenbaum R, Simmons KM, Sims EK, Skyler JS, Smith LB, Speake C, Steck AK, Thomas NPB, Tonyushkina KN, Veijola R, Wentworth JM, Wherrett DK, Wood JR, Ziegler A-G, DiMeglio LA. Diabetes Care, 2024 Aug 1; 47 (8): 1276 - 1298.Journal ArticleConsensus Guidance for Monitoring Individuals With Islet Autoantibody-Positive Pre-Stage 3 Type 1 Diabetes.
DOI:10.2337/dci24-0042 PMID: PMC11381572 -
Mizokami-Stout K, Oshman L, Diez H, Griauzde D, Lee J, Khosrovaneh K, Bhomia N, Kim N, Rau J, Reiss J, Busui R. Diabetes, 2024 Sep 28; 73 (Supplement_1):Proceeding / Abstract / Poster1073-P: Trends in Guideline-Directed Medication Therapy for Type 2 Diabetes in a Statewide Quality Collaborative between 2018–2023
DOI:10.2337/db24-1073-p -
SCHMIDT BM, SPINO C, ROY S, GORDILLO G, HOLMES CM, SEN CK, BUSUI R. Diabetes, 2024 Jun 16; 73 (Supplement_1):Journal Article311-OR: High Transepidermal Water Loss (TEWL) Associates with Failure to Maintain Wound Closure in Diabetic Foot Ulcers
DOI:10.2337/db24-311-or -
ANG L, HUANG Y, MARTIN C, MIZOKAMI-STOUT KR, KUEI LIN Y, VASBINDER A, BANERJEE M, HAYEK S, FELDMAN EL, BUSUI R. Diabetes, 2024 Jun 16; 73 (Supplement_1):Proceeding / Abstract / Poster9-OR: ADA Presidents' Select Abstract: Targeting Inflammation with Salsalate in Type 1 Diabetes Neuropathy (TINSAL-T1DN Trial)
DOI:10.2337/db24-9-or