Thomas Schmidt, PhD
Professor of Internal Medicine
Professor of Microbiology and Immunology
Medical School and Professor of Ecology and Evolutionary Biology
College of Literature, Science, and the Arts
[email protected]
Available to mentor
Thomas Schmidt, PhD
Professor
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Qualifications
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PhDOhio State University, Columbus, OH, United States
1981 - 1985
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MSOhio State University, Columbus, OH, United States
1979 - 1981
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BSUniversity of Michigan, Ann Arbor, MI, United States
1974 - 1978
Center Memberships
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Center MemberRogel Cancer Center
Recent Publications
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de Medeiros MC, Fontaine S, Danella E, Hillman E, Schmidt TM, Furgal A, Wellik DM, Inohara N, Núñez G, Li G, Chen GY, D'Silva NJ. Microbiome, 2026 Apr 10;Journal ArticleLoss of salivary agglutinin induces changes in the salivary microbiome and accelerates development of oral cancer.
DOI:10.1186/s40168-026-02337-5 PMID: 41964098 -
Pudlo NA, Pereira GV, Schaus SR, Yang Q, Fuentes JJ, Jin C, Hein R, Zhang L, Terrapon N, Lyssiotis CA, Schmidt TM, Hansson GC, Luis AS, Martens EC. J Biol Chem, 2026 Mar 17; 111371Journal ArticleThe butyrate-producing Gram-positive human gut bacterium, Hoskinsella mucinilytica, selectively targets host mucin N-acetylhexosamines.
DOI:10.1016/j.jbc.2026.111371 PMID: 41856288 -
Pudlo NA, Pereira GV, Singh S, Pollet RM, Schmidt TM, Pope PB, Chuvochina M, la Rosa SL, Martens EC. International Journal of Systematic and Evolutionary Microbiology, 2026 Jan 1; 76 (1):Journal ArticleDescription of Hoskinsella mucinilytica gen. nov., sp. nov., a mucin-degrading isolate from human faeces, and reclassification of Amedibacillus hominis Abdugheni et al. 2023 as a later heterotypic synonym of Eubacterium hominis Liu et al. 2022 within the genus Hoskinsella gen. nov.
DOI:10.1099/ijsem.0.007038 PMID: 41568592 -
Gao J, Lee AA, Abtahi S, Turner JR, Grover M, Schmidt A, Schmidt TM, Nee JW, Iturrino J, Lembo A, Chey WD, Wiley JW, Singh P. Gastroenterology, 2025 Oct 13;Journal ArticleLow Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Diet Improves Colonic Barrier Function and Mast Cell Activation in Patients With Diarrhea-Predominant Irritable Bowel Syndrome: A Mechanistic Trial.
DOI:10.1053/j.gastro.2025.07.016 -
Solanki S, Taranto J, Rebernick R, Castillo C, Ponnusamy V, Sykes MM, Leiser SF, Lee JH, Schmidt T, Shah YM. Journal of Nutrition, 2025 Jun 1; 155 (6): 1804 - 1817.Journal ArticleLow Protein Diet Exacerbates Experimental Mouse Models of Colitis through Epithelial Autonomous and Nonautonomous Mechanisms
DOI:10.1016/j.tjnut.2025.03.031 PMID: 40216295 -
Pang Z, Cady N, Cen L, Schmidt TM, He X, Li J. 2025 Jan 14;PreprintPhysiologically Relevant Coculture Model for Oral Microbial-Host Interactions.
DOI:10.1101/2025.01.10.632380 PMID: 39868140 -
Awad D, Attebury H, Hong R, Kim K, Zhang L, Bischoff A, deDekker A, Hoostal M, Nieto Carrion JA, Nelson NS, Strayhorn C, Frankel T, di Magliano MP, Lyssiotis CA, Schmidt TM, Daley D. 2024 Dec 3;PreprintIsolation and characterization of microbiota from human pancreatic tumors and small intestine.
DOI:10.1101/2024.11.27.625762 PMID: 39677718 -
Kuffa P, Pickard JM, Campbell A, Yamashita M, Schaus SR, Martens EC, Schmidt TM, Inohara N, Núñez G, Caruso R. Cell Host and Microbe, 2023 Dec 13; 31 (12): 2007 - 2022.e12.Journal ArticleFiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont
DOI:10.1016/j.chom.2023.10.016 PMID: 37967555
Featured News & Stories
Department News
What we do in M&I: A gutsy dive into the microbiome
Have you ever wondered about the hidden microbial world inside your gut? Dive into the fascinating study of the molecules that fuel our energy or learn how a high fiber diet can do wonders for your gut. From the life-saving early detection of colon cancer to finding possible treatments for inflammatory bowel diseases and C diff. infection, M&I cutting-edge research is transforming our understanding of the biology that impacts our health and is shaping the future of healthcare.
Department News
Congratulations Austin Campbell
Dr. Campbell defended his dissertation