![](https://medschool.umich.edu/sites/default/files/styles/square_1_1/public/2024-02/Gallagher_Katherine_web.jpg?h=d94c4b90&itok=YOreod5s)
Available to mentor
![](https://medschool.umich.edu/sites/default/files/styles/square_1_1/public/2024-02/Gallagher_Katherine_web.jpg?h=d94c4b90&itok=YOreod5s)
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Residency, General SurgeryUniversity of Maryland Medical Center, Baltimore, MD, United States
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Postdoctoral Fellow, Vascular SurgeryUniversity of Pennsylvania Hospital, Philadelphia, PA, United States
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Fellowship, Vascular SurgeryWeill Cornell Medical Center, Columbia University Hospital, New York, NY, United States
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MDUniversity of Maryland School of Medicine, 655 W. Baltimore Street, 2002
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BSUniversity of Maryland, College Park, 1998
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center MemberCaswell Diabetes Institute
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Center MemberTaubman Institute
Dr. Gallagher has had a long-standing defined clinical and translational interest in the mechanisms underlying impaired diabetic wound healing. Her long-term goal is to uncover the basic mechanisms responsible for the coordination of immune cells in early tissue repair processes, determine impairments in Type 2 Diabetes and translate this knowledge to the bedside. It is my belief that the diabetic phenotype has systemic effects on bone marrow cells that alter innate immune cell phenotypes resulting in impaired peripheral wound healing.
Since joining the faculty at the University of Michigan, Dr. Gallagher's research has focused on histone methylation changes in bone marrow progenitor cells and the impact on peripheral macrophage phenotypes as it relates to wound healing and inflammation. This work will provide important data on inflammatory macrophages in peripheral tissue and their contribution to chronic inflammation and may lead to novel treatment modalities. I have also trained numerous post-doctoral fellows/residents in my lab under NIH T32, F32, AAS grant, VESS grant and other funding mechanisms. I have a strong interest in training postdocs/residents in translational science.
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Entrup GP, Unadkat A, Warheit-Niemi HI, Thomas B, Gurczynski SJ, Cui Y, Smith AM, Gallagher KA, Moore BB, Singer K. J Immunol, 2024 Jun 21;Journal ArticleObesity Inhibits Alveolar Macrophage Responses to Pseudomonas aeruginosa Pneumonia via Upregulation of Prostaglandin E2 in Male, but Not Female, Mice.
DOI:10.4049/jimmunol.2400140 PMID: 38905107 -
Moon JY, Gallagher KA. Immunity, 2024 Jul 9; 57 (7): 1448 - 1451.Journal ArticleScavengers in islets fuel diabetic autoimmunity.
DOI:10.1016/j.immuni.2024.06.008 PMID: 38986438 -
Bauer T, Mangum KD, Barrett E, Joshi A, Buckley S, Gudjonsson J, Davis F, Obi A, Moore B, Gallagher K. Journal of Vascular Surgery, 2024 Jun; 79 (6): e214Proceeding / Abstract / PosterImpaired Epigenetic Reprogramming prevents Fibroblast to Myofibroblast Transition in Diabetic Wounds
DOI:10.1016/j.jvs.2024.03.274 -
Mangum KD, Bauer T, Joshi A, Wolf-Fortune S, Moon J, Li Q, Gudjonsson J, Obi A, Davis F, Gallagher K. Journal of Vascular Surgery, 2024 Jun; 79 (6): e292Proceeding / Abstract / PosterThe Histone Demethylase JMJD3 Regulates Smooth Muscle Cell Phenotype during Macrophage-mediated Inflammation
DOI:10.1016/j.jvs.2024.03.376 -
Bauer TM, Gallagher KA. J Clin Invest, 2024 Feb 1; 134 (3):Journal ArticleBiofilm-derived oxylipin 10-HOME mediated immune response in women with breast implants.
DOI:10.1172/JCI176547 PMID: 38299590 -
Ladner DP, Goldstein AM, Billiar TR, Cameron AM, Carpizo DR, Chu DI, Coopersmith CM, DeMatteo RP, Feng S, Gallagher KA, Gillanders WE, Lal BK, Lipshutz GS, Liu A, Maier RV, Mittendorf EA, Morris AM, Sicklick JK, Velazquez OC, Whitson BA, Wilke LG, Yoon SS, Zeiger MA, Farmer DL, Hwang ES, ASA Task Force for Research Sustainability . Ann Surg, 2024 Feb 1; 279 (2): 231 - 239.Journal ArticleTransforming the Future of Surgeon-Scientists.
DOI:10.1097/SLA.0000000000006148 PMID: 37916404 -
Gallagher KA, Mills JL, Armstrong DG, Conte MS, Kirsner RS, Minc SD, Plutzky J, Southerland KW, Tomic-Canic M, American Heart Association Council on Peripheral Vascular Disease; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; and Council on Lifestyle and Cardiometabolic Health . Circulation, 2024 Jan 23; 149 (4): e232 - e253.Journal ArticleCurrent Status and Principles for the Treatment and Prevention of Diabetic Foot Ulcers in the Cardiovascular Patient Population: A Scientific Statement From the American Heart Association.
DOI:10.1161/CIR.0000000000001192 PMID: 38095068 -
Audu CO, Wolf SJ, Joshi AD, Moon JY, Melvin WJ, Sharma SB, Davis FM, Obi AT, Wasikowski R, Tsoi LC, Barrett EC, Mangum KD, Bauer TM, Kunkel SL, Moore BB, Gallagher KA. JCI Insight, 2024 Jun 24; 9 (12):Journal ArticleHistone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells.
DOI:10.1172/jci.insight.172959 PMID: 38912581