Available to mentor
Current research efforts are concentrated in three main areas: (1) development and implementation of low cost technology systems for quantitative human phenotyping, (2) development and implementation of low cost technology systems for equitable health care delivery, and (3) quantitative trait analysis of complex, multigenic, late-life and time-dependent traits.
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Howard Hughes Medical Institute FellowPrinceton University, Molecular Biology, 1991
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PhDWashington University in St. Louis School of Medicine, St Louis, 1988
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BSUniversity of Rochester, Rochester, 1982
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Center MemberGlobal REACH
The cross-disciplinary research seeks obtain longitudinal phenotype trajectories in diverse human populations to understand gene-by-environment and gene-by-time interactions. The work addresses a fundamental biological question: “What are the human genetic variations that impact the changes observed in an individual’s phenotype over their life-course?” The core strategic challenge is the use of real-world human populations to understand the genetic and environmental interactions of longitudinal biological change. The work focuses on technologies for quantitative, reproducible phenotyping of large and diverse human populations.
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Osafo C, Thomford NE, Coleman J, Carboo A, Guure C, Okyere P, Adu D, Adanu R, Parekh RS, Burke D. PLoS One, 2022 17 (12): e0278115Journal ArticleAPOL1 genotype associated risk for preeclampsia in African populations: Rationale and protocol design for studies in women of African ancestry in resource limited settings.
DOI:10.1371/journal.pone.0278115 PMID: 36580463 -
Musser JA, Cho J, Cohn A, Niziol LM, Ballouz D, Burke DT, Newman-Casey PA. BMC Ophthalmol, 2022 Jun 28; 22 (1): 283Journal ArticleMeasuring impact of a quality improvement initiative on glaucoma clinic flow using an automated real-time locating system.
DOI:10.1186/s12886-022-02495-8 PMID: 35764976 -
Musser JA, Cho J, Cohn A, Niziol LM, Ballouz D, Burke DT, Newman-Casey PA. 2022 Jun 28;Journal ArticleMeasuring impact of a quality improvement initiative on glaucoma clinic flow using an automated real-time locating system
DOI:10.7302/5331 -
Choudhury A, Aron S, Botigué LR, Sengupta D, Botha G, Bensellak T, Wells G, Kumuthini J, Shriner D, Fakim YJ, Ghoorah AW, Dareng E, Odia T, Falola O, Adebiyi E, Hazelhurst S, Mazandu G, Nyangiri OA, Mbiyavanga M, Benkahla A, Kassim SK, Mulder N, Adebamowo SN, Chimusa ER, Muzny D, Metcalf G, Gibbs RA, TrypanoGEN Research Group , Rotimi C, Ramsay M, H3Africa Consortium , Adeyemo AA, Lombard Z, Hanchard NA. Nature, 2020 Oct; 586 (7831): 741 - 748.Journal ArticleHigh-depth African genomes inform human migration and health.
DOI:10.1038/s41586-020-2859-7 PMID: 33116287 -
Newman-Casey PA, Musser J, Niziol LM, Shedden K, Burke D, Cohn A. J Biomed Inform, 2020 Jun; 106: 103428Journal ArticleDesigning and validating a low-cost real time locating system to continuously assess patient wait times.
DOI:10.1016/j.jbi.2020.103428 PMID: 32339749 -
Payne N, Gangwani R, Barton K, Sample AP, Cain SM, Burke DT, Newman-Casey PA, Shorter KA. Sensors (Basel), 2020 Apr 24; 20 (8):Journal ArticleMedication Adherence and Liquid Level Tracking System for Healthcare Provider Feedback.
DOI:10.3390/s20082435 PMID: 32344754 -
Kc R, Srivastava A, Wilkowski JM, Richter CE, Shavit JA, Burke DT, Bielas SL. Sci Rep, 2016 Aug 25; 6: 32048Journal ArticleDetection of nucleotide-specific CRISPR/Cas9 modified alleles using multiplex ligation detection.
DOI:10.1038/srep32048 PMID: 27557703 -
Osafo C, Raji YR, Burke D, Tayo BO, Tiffin N, Moxey-Mims MM, Rasooly RS, Kimmel PL, Ojo A, Adu D, Parekh RS, H3Africa Kidney Disease Research Network Investigators as members of The H3Africa Consortium . Clin J Am Soc Nephrol, 2015 Dec 7; 10 (12): 2279 - 2287.Journal ArticleHuman Heredity and Health (H3) in Africa Kidney Disease Research Network: A Focus on Methods in Sub-Saharan Africa.
DOI:10.2215/CJN.11951214 PMID: 26138261
