Brian C Callaghan, MD, MS
Eva L Feldman
Professor and Professor of Neurology
109 Zina Pitcher Pl, 4021 BSRB
Ann Arbor, Michgan 48109-2200
[email protected]

Available to mentor

Brian C Callaghan, MD, MS
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Dr. Callaghan is an Associate Professor of Neurology and a neuromuscular specialist at the University of Michigan. He completed his medical degree and neurology residency at the University of Pennsylvania and completed a fellowship in neuromuscular disease at the University of Michigan. He also completed a master’s degree program in clinical research at the University of Michigan School of Public Health.

    • Fellowship
      Center for Healthcare Research and Transformation Policy, University of Michigan, Ann Arbor, Michigan, 2016
    • Fellowship
      University of Michigan Health System, Neuromuscular, 2009
    • Residency
      University of Pennsylvania Medical Center, Neurology, 2008
    • Internship, Preliminary Medicine
      University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, 2005
    • MS
      University of Michigan, Ann Arbor, 2011
    • MD
      University of Pennsylvania Medical Center, 3400 Spruce Street, 2004
    • BS
      University of Michigan, Ann Arbor, 1999
    Center Memberships
    • Center Member
      Caswell Diabetes Institute
    • Center Member
      Institute for Healthcare Policy and Innovation
    Research Overview

    Dr. Callaghan is interested in the treatment of painful diabetic neuropathy and other chronic pain conditions including the role of opioids. He has led the recent American Academy of Neurology guideline on the treatment of painful diabetic neuropathy and is interested in better understanding the best interventions for this common condition. Furthermore, Dr. Callaghan is interested in a better understanding of the appropriate role of opioids in chronic non cancer pain conditions.

    Recent Publications See All Publications
    • Journal Article
      The effect of surgical weight loss on diabetes complications in individuals with class II/III obesity.
      Reynolds EL, Watanabe M, Banerjee M, Chant E, Villegas-Umana E, Elafros MA, Gardner TW, Pop-Busui R, Pennathur S, Feldman EL, Callaghan BC. Diabetologia, 2023 Jul; 66 (7): 1192 - 1207. DOI:10.1007/s00125-023-05899-3
      PMID: 36917280
    • Journal Article
      Open Peer Review Reports: A Pilot Project in Neurology®.
      Baskin PK, Barkhof F, Burch R, Callaghan BC, Ciccarelli O, Hedera P, Hershey LA, Jobst BC, Pieper KM, Quimby SL, Rahkola A, Schneider AL, Worrall BB, Wusthoff CJ, Merino JG. Neurology, 2024 May 14; 102 (9): e209462 DOI:10.1212/WNL.0000000000209462
      PMID: 38608230
    • Journal Article
      Burden of Neurologic Health Care and Incident Neurologic Diagnoses in the Year After COVID-19 or Influenza Hospitalization.
      de Havenon A, Callaghan BC, Xu Y, Connor M, Hill CE, Ney J, Esper GJ. Neurology, 2024 Apr 23; 102 (8): e209248 DOI:10.1212/WNL.0000000000209248
      PMID: 38507675
    • Journal Article
      Safety and Efficacy of Topiramate in Individuals With Cryptogenic Sensory Peripheral Neuropathy With Metabolic Syndrome: The TopCSPN Randomized Clinical Trial.
      Smith AG, Singleton JR, Aperghis A, Coffey CS, Creigh P, Cudkowicz M, Conwit R, Ecklund D, Fedler JK, Gudjonsdottir A, Hauer P, Herrmann DN, Kearney M, Kissel J, Klingner E, Quick A, Revere C, Stino A, NeuroNEXT NN108 TopCSPN Study Team . JAMA Neurol, 2023 Dec 1; 80 (12): 1334 - 1343. DOI:10.1001/jamaneurol.2023.3711
      PMID: 37870862
    • Journal Article
      Prescription Opioid Initiation for Neuropathy, Headache, and Low Back Pain: A US Population-based Medicare Study.
      Lin CC, Callaghan BC, Burke JF, Kerber KA, Bicket MC, Esper GJ, Skolarus LE, Hill CE. J Pain, 2023 Dec; 24 (12): 2268 - 2282. DOI:10.1016/j.jpain.2023.07.011
      PMID: 37468023
    • Journal Article
      The Effect of Surgical Weight Loss on Cognition in Individuals with Class II/III Obesity.
      Reynolds EL, Votruba KL, Watanabe M, Banerjee M, Elafros MA, Chant E, Villegas-Umana E, Giordani B, Feldman EL, Callaghan BC. J Nutr Health Aging, 2023 27 (12): 1153 - 1161. DOI:10.1007/s12603-023-2047-1
      PMID: 38151865
    • Journal Article
      Cost and utilization of healthcare services for persons with diabetes.
      Reynolds EL, Mizokami-Stout K, Putnam NM, Banerjee M, Albright D, Ang L, Lee J, Pop-Busui R, Feldman EL, Callaghan BC. Diabetes Res Clin Pract, 2023 Nov; 205: 110983 DOI:10.1016/j.diabres.2023.110983
      PMID: 37890702
    • Journal Article
      Patient Travel Distance to Neurologist Visits.
      Lin CC, Hill CE, Kerber KA, Burke JF, Skolarus LE, Esper GJ, de Havenon A, De Lott LB, Callaghan BC. Neurology, 2023 Oct 31; 101 (18): e1807 - e1820. DOI:10.1212/WNL.0000000000207810
      PMID: 37704403
    Featured News & Stories obese person walking with a shadow stretched out behind them
    Research News
    Obesity-related Neuropathy: The New Epidemic
    Researchers reviewed the latest research on obesity-related neuropathy and possible treatment options.
    microfage cell with lipids
    Research News
    Blood Fat Linked to Neuropathy
    Neurology published findings from an international group of scientists, including Brian Callaghan, M.D., M.S., that linked blood fatty acid levels to neuropathy.
    photo of Brian Callaghan
    Research News
    Research On Neurologic Burden of COVID vs Flu Covered By Numerous Media Outlets
    Recently published research by Dr. Brian Callaghan on whether influenza or COVID had a higher neurological burden was covered by U.S. News & World Report, Daily Mail, Science Magazine,, and many more.
    photo of Brian Callaghan
    Research News
    Is the Burden of Neurologic Disease Higher After Influenza or COVID-19?
    Brian Callaghan, M.D., M.S., authored research published in Neurology, the official journal of the American Academy of Neurology, that answered just that.
    photo of Brian Callaghan and Evan Reynolds
    Research News
    Drs. Reynolds and Callaghan Speak to U.S. News About Out-of-Pocket Diabetes Costs
    U.S. News & World Report featured Drs. Evan Reynolds and Brian Callaghan, whose recent study found that total and out-of-pocket costs for diabetics run hundreds to thousands of dollars more than regular medical expenses for people without diabetes.
    doctor measuring waistline
    Research News
    Examining cognitive health benefits and stigma of surgery as weight management tool
    Nutritional Insight interviewed Brian Callaghan, M.D., on new research published in the Journal of Nutrition, Health & Aging.