CCMB Seminar: Indika Rajapakse, PhD CCMB Seminar Series Event Series
Date:
Wednesday, January 15, 2025
Time:
4:00 pm to 5:00 pm
Location:

Palmer Commons, Forum Hall

Zoom link
About This Event

"Foundations for Digital Biology"

Presented by Indika Rajapakse, PhD

Abstract:

Digital twins will empower scientists to engineer biology. In this talk, I will present the construction of a data-guided, universal network for the human genome. From this universal network called the Hardwired Genome (HWG), we can query cell-type-specific wiring and explore how perturbations affect information flow. I will also introduce a numerical prototype which extends hardwiring theory to tissue dynamics and is based on the Kuramoto oscillator, called the Mesmerizer, developed with Steve Smale and Cleve Moler. Finally, I will discuss how combining the HWG and the Mesmerizer can lay the foundation for digital biology.
Presenters
Indika Rajapakse

Professor
Host/Moderator
Brian D. Athey

Professor
Upcoming Events View All Upcoming Events
Tools and Technology Seminar: Sion Kim
"Identifying Chromatin Jets in Loop Extrusion and Replication Processes" presented by Sion Kim (DCMB)
CCMB Seminar: Chase Weidmann, PhD
Join the U-M CCMB/DCMB Seminar Series on bioinformatics, Wednesdays at 4 PM EST, Palmer Commons. Featuring guest speakers, sponsored by Computational Medicine & Bioinformatics.
Tools and Technology Seminar: James Boyko
"Correlated character evolution with hidden Markov models and applications in antibiotic resistance evolution" presented by James Boyko (MIDAS)
CCMB Seminar: Morgan Levine, PhD
Join the U-M CCMB/DCMB Seminar Series on bioinformatics, Wednesdays at 4 PM EST, Palmer Commons. Featuring guest speakers, sponsored by Computational Medicine & Bioinformatics.
Tools and Technology Seminar: Hye Kyong Kweon
“Exploring the Potential of Sulfoproteomics: Overcoming Challenges and Applying to Large-Scale Proteomics” presented by Hye Kyong Kweon (Chemistry)
Tools and Technology Seminar: Yue Zhao
“CEDA: integrating gene expression data with CRISPR-pooled screen data identifies essential genes with higher expression” presented by Yue Zhao (DCMB)
CCMB Seminar: Todd Hollon, PhD
Join the U-M CCMB/DCMB Seminar Series on bioinformatics, Wednesdays at 4 PM EST, Palmer Commons. Featuring guest speakers, sponsored by Computational Medicine & Bioinformatics.
Tools and Technology Seminar: Liyue Shen
“Enhance Efficiency of Diffusion-based Generative Models for Solving Inverse Problems via Posterior Sampling” presented by Liyue Shen (Electrical Engineering & Computer Science)
CCMB Seminar: Wenbo Li, PhD
Join the U-M CCMB/DCMB Seminar Series on bioinformatics, Wednesdays at 4 PM EST, Palmer Commons. Featuring guest speakers, sponsored by Computational Medicine & Bioinformatics.
Tools and Technology Seminar: Wenjing Ma
"Optimal transport analysis of spatial transcriptomics reveals spatial domain development along time trajectories" presented by Wenjing Ma (Biostatistics)
DCMB Industry Day
Have you ever wondered what it is like to work in the biotechnology industry? Are you interested in hearing from industry insiders about how they got started and what skills employers are looking for today? Please join us for the 6th Annual DCMB Industry Day!
Tools and Technology Seminar: Mason Ferlic
“Rethinking Randomizations: A SMART Approach to Optimizing Adaptive Interventions” presented by Mason Ferlic (Statistics; Data Science for Dynamic Intervention Decision-Making Center)
CCMB Seminar: Peter Park, PhD
Join the U-M CCMB/DCMB Seminar Series on bioinformatics, Wednesdays at 4 PM EST, Palmer Commons. Featuring guest speakers, sponsored by Computational Medicine & Bioinformatics.
Tools and Technology Seminar: Mahnoor Gondal
Presented by Mahnoor Gondal
CCMB Seminar: Jason H. Moore, PhD
Professor of Biomedical Informatics; Director, Bioinformatics and Integrative Genomics (BIG) PhD Track
Tools and Technology Seminar: Monica Holmes
Presented by Monica Holmes (DCMB)
CDB Elevator Pitch Workshop
Learn how to craft a compelling elevator pitch
M&I Seminar Series: Vince Young
M&I Seminar Series
Pharmacology Seminar - Dr. Ada Eban-Rothschild
Pharmacology Seminar - Dr. Ada Eban-Rothschild
Wednesday Seminars by Trainees Series (WeST)
Part of the Wednesday Seminars by Trainees Series (WeST)
2025 CDB Seminar
Ashley Libby, PhD, will present "CRISPy Chickens - Genetically coordinated cell fate transitions in neural tube development.
M&I Seminar Series: David Masopust
David Masopust, McKnight University Professor HHMI Faculty Scholar at the University of Minnesota
Intraretinal Stimulation for High Resolution Artificial Vision
Part of the Hearing, Balance and Chemical Sense seminar series.
Photo realistic rendering of neurons
Pharmacology Seminar - Dr. Scott Soderling
Pharmacology Seminar - Dr. Scott Soderling
Wednesday Seminars by Trainees Series (WeST)
Part of the Wednesday Seminars by Trainees Series (WeST)
Matthew Brody, Ph.D. - Pfizer Upjohn Early Career Research Professorship in Molecular Pharmacology Ceremony
Matthew Brody, Ph.D. Ceremony (Pfizer Upjohn Early Career Research Professorship in Molecular Pharmacology)
Matthew Brody headshot
M&I Seminar Series: Deanna Kulpa
Deanna Kulpa, Emory University
Beyond Amyloid: Seeking to Understand the Diverse Causes of Age-related Dementia at the Michigan Alzheimer’s Disease Center
Part of the Hearing, Balance and Chemical Sense seminar series.
Photo realistic rendering of neurons
2025 CDB Seminar
Nicole Edwards, Ph.D., will present "Discovering the development basis of trachea-esophageal congenital anomalies."