1301 Catherine Street, Medical Sciences Building 1, room 6446
Ann Arbor, Michigan 48109
Available to mentor
My research specializes in integrating acoustics, mechanics, and material science to advance biomedical applications of ultrasound. The key technique utilized is acoustic droplet vaporization (ADV), which is the vaporization of perfluorocarbon liquid droplets using short ultrasound pulses. My lab focus is on comprehending the fundamental physics of ADV, essential for tailoring its use in specific applications like in situ microrheology and targeted drug delivery. To achieve this, we use ultras-high-speed microscopy, theoretical modeling, acoustic measurements, and confocal imaging to elucidate the mechanism involved and optimize for specific applications.
https://www.ultrasound.med.umich.edu/principal-investigators/mitra-aliabouzar https://scholar.google.com/citations?hl=en&user=F91Xl6kAAAAJ&view_op=list_works&sortby=pubdate
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Postdoctoral Research FellowUniversity of Michigan Medical School, Radiology, 2022
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PhD in Mechanical EngineeringGeorge Washington University, Washington D.C., 2018
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Master of Science in Biomedical EngineeringSharif University of Technology, Tehran, 2011
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Bachelor of Science in Biomedical EngineeringTehran Polytechnic, Tehran, 2008
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Center MemberSamuel and Jean Frankel Cardiovascular Center
* Understanding the release mechanisms and transport dynamics of ultrasound responsive therapeutic agents via ultra high speed imaging
* Characterizing micro-mechanical properties of biomaterials via acoustic and microscopic techniques using acoustic droplet vaporization and high speed rheometry
* Developing acoustic mapping techniques for real-time monitoring and quantification of ultrasound therapy
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Abeid BA, Fabiilli ML, Estrada JB, Aliabouzar M. Ultrason Sonochem, 2024 Feb; 103: 106754Journal ArticleUltra-high-speed dynamics of acoustic droplet vaporization in soft biomaterials: Effects of viscoelasticity, frequency, and bulk boiling point.
DOI:10.1016/j.ultsonch.2024.106754 PMID: 38252981 -
Aliabouzar M, Abeid BA, Estrada JB, Fabiilli ML. The Journal of the Acoustical Society of America, 2023 Oct 1; 154 (4_supplement): a51 - a52.Journal ArticleUltra-fast mechanics and bioeffects of acoustic droplet vaporization in tissue-mimicking hydrogels
DOI:10.1121/10.0022767 -
Aliabouzar M, Abeid BA, Kripfgans OD, Fowlkes JB, Estrada JB, Fabiilli ML. Appl Phys Lett, 2023 Sep 11; 123 (11): 114101Journal ArticleReal-time spatiotemporal characterization of mechanics and sonoporation of acoustic droplet vaporization in acoustically responsive scaffolds.
DOI:10.1063/5.0159661 PMID: 37705893 -
Aliabouzar M, Kripfgans OD, Brian Fowlkes J, Fabiilli ML. Z Med Phys, 2023 Aug; 33 (3): 387 - 406.Journal ArticleBubble nucleation and dynamics in acoustic droplet vaporization: a review of concepts, applications, and new directions.
DOI:10.1016/j.zemedi.2023.01.004 PMID: 36775778 -
Aliabouzar M, Quesada C, Chan ZQ, Fowlkes JB, Franceschi RT, Putnam AJ, Fabiilli ML. Acta Biomater, 2023 Jul 1; 164: 195 - 208.Journal ArticleAcoustic droplet vaporization for on-demand modulation of microporosity in smart hydrogels.
DOI:10.1016/j.actbio.2023.04.037 PMID: 37121372 -
Aliabouzar M. The Journal of the Acoustical Society of America, 2022 Oct 1; 152 (4): a76 - a76.Journal ArticleProbing the mechanisms of acoustic droplet vaporization
DOI:10.1121/10.0015600 -
Azami RH, Aliabouzar M, Osborn J, Kumar KN, Forsberg F, Eisenbrey JR, Mallik S, Sarkar K. Ultrasound Med Biol, 2022 Sep; 48 (9): 1720 - 1732.Journal ArticleMaterial Properties, Dissolution and Time Evolution of PEGylated Lipid-Shelled Microbubbles: Effects of the Polyethylene Glycol Hydrophilic Chain Configurations.
DOI:10.1016/j.ultrasmedbio.2022.04.216 PMID: 35697583 -
Aliabouzar M, Kripfgans OD, Estrada JB, Brian Fowlkes J, Fabiilli ML. Ultrason Sonochem, 2022 Aug; 88: 106090Journal ArticleMulti-time scale characterization of acoustic droplet vaporization and payload release of phase-shift emulsions using high-speed microscopy.
DOI:10.1016/j.ultsonch.2022.106090 PMID: 35835060