Mitra Aliabouzar
Research Assistant Professor, Radiology
Assistant Research Scientist, Mechanical Engineering
Radiology Department
1301 Catherine Street, Medical Sciences Building 1, room 6446
Ann Arbor, Michigan 48109
[email protected]

Available to mentor

Mitra Aliabouzar
Research Assistant Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    My research specializes in integrating acoustics, mechanics, and material science to advance biomedical applications of ultrasound. The key technique utilized is acoustic droplet vaporization (ADV), which is the vaporization of perfluorocarbon liquid droplets using short ultrasound pulses. My lab focus is on comprehending the fundamental physics of ADV, essential for tailoring its use in specific applications like in situ microrheology and targeted drug delivery. To achieve this, we use ultras-high-speed microscopy, theoretical modeling, acoustic measurements, and confocal imaging to elucidate the mechanism involved and optimize for specific applications.

    Links
    • https://www.ultrasound.med.umich.edu/principal-investigators/mitra-aliabouzar
    • https://scholar.google.com/citations?hl=en&user=F91Xl6kAAAAJ&view_op=list_works&sortby=pubdate
    Qualifications
    • Postdoctoral Research Fellow
      University of Michigan Medical School, Radiology, 2022
    • PhD in Mechanical Engineering
      George Washington University, Washington D.C., 2018
    • Master of Science in Biomedical Engineering
      Sharif University of Technology, Tehran, 2011
    • Bachelor of Science in Biomedical Engineering
      Tehran Polytechnic, Tehran, 2008
    Center Memberships
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    Research Overview

    * Understanding the release mechanisms and transport dynamics of ultrasound responsive therapeutic agents via ultra high speed imaging
    * Characterizing micro-mechanical properties of biomaterials via acoustic and microscopic techniques using acoustic droplet vaporization and high speed rheometry
    * Developing acoustic mapping techniques for real-time monitoring and quantification of ultrasound therapy

    Recent Publications See All Publications
    • Journal Article
      Ultra-high-speed dynamics of acoustic droplet vaporization in soft biomaterials: Effects of viscoelasticity, frequency, and bulk boiling point.
      Abeid BA, Fabiilli ML, Estrada JB, Aliabouzar M. Ultrason Sonochem, 2024 Feb; 103: 106754 DOI:10.1016/j.ultsonch.2024.106754
      PMID: 38252981
    • Journal Article
      Ultra-fast mechanics and bioeffects of acoustic droplet vaporization in tissue-mimicking hydrogels
      Aliabouzar M, Abeid BA, Estrada JB, Fabiilli ML. The Journal of the Acoustical Society of America, 2023 Oct 1; 154 (4_supplement): a51 - a52. DOI:10.1121/10.0022767
    • Journal Article
      Real-time spatiotemporal characterization of mechanics and sonoporation of acoustic droplet vaporization in acoustically responsive scaffolds.
      Aliabouzar M, Abeid BA, Kripfgans OD, Fowlkes JB, Estrada JB, Fabiilli ML. Appl Phys Lett, 2023 Sep 11; 123 (11): 114101 DOI:10.1063/5.0159661
      PMID: 37705893
    • Journal Article
      Bubble nucleation and dynamics in acoustic droplet vaporization: a review of concepts, applications, and new directions.
      Aliabouzar M, Kripfgans OD, Brian Fowlkes J, Fabiilli ML. Z Med Phys, 2023 Aug; 33 (3): 387 - 406. DOI:10.1016/j.zemedi.2023.01.004
      PMID: 36775778
    • Journal Article
      Acoustic droplet vaporization for on-demand modulation of microporosity in smart hydrogels.
      Aliabouzar M, Quesada C, Chan ZQ, Fowlkes JB, Franceschi RT, Putnam AJ, Fabiilli ML. Acta Biomater, 2023 Jul 1; 164: 195 - 208. DOI:10.1016/j.actbio.2023.04.037
      PMID: 37121372
    • Journal Article
      Probing the mechanisms of acoustic droplet vaporization
      Aliabouzar M. The Journal of the Acoustical Society of America, 2022 Oct 1; 152 (4): a76 - a76. DOI:10.1121/10.0015600
    • Journal Article
      Material Properties, Dissolution and Time Evolution of PEGylated Lipid-Shelled Microbubbles: Effects of the Polyethylene Glycol Hydrophilic Chain Configurations.
      Azami RH, Aliabouzar M, Osborn J, Kumar KN, Forsberg F, Eisenbrey JR, Mallik S, Sarkar K. Ultrasound Med Biol, 2022 Sep; 48 (9): 1720 - 1732. DOI:10.1016/j.ultrasmedbio.2022.04.216
      PMID: 35697583
    • Journal Article
      Multi-time scale characterization of acoustic droplet vaporization and payload release of phase-shift emulsions using high-speed microscopy.
      Aliabouzar M, Kripfgans OD, Estrada JB, Brian Fowlkes J, Fabiilli ML. Ultrason Sonochem, 2022 Aug; 88: 106090 DOI:10.1016/j.ultsonch.2022.106090
      PMID: 35835060