109 Zina Pitcher Place, Biomedical Science Research Building A502
Ann Arbor, MI 48109
Available to mentor
Dr. Galban is a Research Associate Professor of Radiology with a dual appointment in the Department of Surgery. She is Associate Director of the Center for Basic and Translational Science and a member of the Center for Molecular Imaging and the Rogel Cancer Center. Dr. Galban’s group focuses on developing and establishing imaging technologies and mouse models of various malignancies recapitulating human disease with the goal of developing novel therapies. Ongoing projects in Dr. Galban’s lab include investigating the mechanisms of molecularly targeted and immune-based therapies utilizing imaging in cell culture and mouse models in the lethal pediatric brain tumor Diffuse Intrinsic Pontine Glioma (DIPG), with particular focus on targeting cancer stem cells in DIPG and other pediatric gliomas; resistance mechanisms in the tumor microenvironment in KRAS-mutant lung cancer, facilitated by use of KrasG12D inducible and reversible genetically engineered mouse models of NSCLC and patient derived organoids; and identifying molecular and imaging biomarkers for early diagnosis of lung cancer in patients with idiopathic pulmonary fibrosis. Dr. Galban was the recipient of the University of Michigan Medical School’s Research Faculty Recognition Award in 2021 and the medical school’s Endowment for Basic Sciences Teaching Award in 2023.
https://medicine.umich.edu/dept/radiology/stefanie-galban-phd
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Postdoctoral FellowshipUniversity of Michigan, Pathology, 2009
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Postdoctoral FellowNational Institute on Aging, Cellular and Molecular Biology, 2006
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Postdoctoral FellowshipHeinrich Heine University Düsseldorf, Biochemistry and Molecular Biology, 2004
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PhDJohannes Gutenberg University, Mainz, 2003
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MSJohannes Gutenberg University, Mainz, 1999
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Center MemberRogel Cancer Center
• Generation of genetically engineered mouse models of cancer.
• Use of molecular imaging as a tool to facilitate understanding of oncogenesis.
• Identification of prognostic markers and surrogate biomarkers in cancer.
• Immune-oncology: understanding the tumor microenvironment to enhance therapeutic efficacy.
• Development of new therapeutic paradigms for pediatric brain tumors.
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Bell AJ, Pal R, Labaki WW, Hoff BA, Wang JM, Murray S, Kazerooni EA, Galban S, Lynch DA, Humphries SM, Martinez FJ, Hatt CR, Han MK, Ram S, Galban CJ. Respir Res, 2024 Feb 28; 25 (1): 106Journal ArticleLocal heterogeneity of normal lung parenchyma and small airways disease are associated with COPD severity and progression.
DOI:10.1186/s12931-024-02729-x PMID: 38419014 -
Hinshaw R, Espinoza C, Zhang Y, Pasca di Magliano M, Galban S. Cancer Immunology Research, 2024 Oct 18; 12 (10_Supplement): b019 - b019.Journal ArticleAbstract B019: Investigating the role of antigen-presenting fibroblasts in the tumor microenvironment of non-small cell lung cancer
DOI:10.1158/2326-6074.tumimm24-b019 -
Bell AJ, Ram S, Labaki WW, Murray S, Kazerooni EA, Galban S, Martinez FJ, Hatt CR, Wang JM, Ivanov V, McGettigan P, Khokhlovich E, Maiorino E, Suryadevara R, Boueiz A, Castaldi P, Mirkes EM, Zinovyev A, Gorban AN, Galban CJ, Han MK. Am J Respir Crit Care Med, 2024 Sep 13;Journal ArticleTemporal Exploration of COPD Phenotypes: Insights from the COPDGene and SPIROMICS Cohorts.
DOI:10.1164/rccm.202401-0127OC PMID: 39269427 -
Cartaxo R, Nieblas-Bedolla E, Niculcea M, Miclea M, Siada R, Schwark K, Ji S, Gera A, Doherty R, Galban S, Nuechterlein N, Hara T, Parent J, Filbin M, Koschmann C. Neuro-Oncology, 2024 Jun 18; 26 (Supplement_4):Journal ArticleHGG-52. MULTI-INTEGRIN TARGETING EFFECTIVELY SUPPRESSES DIFFUSE MIDLINE GLIOMA MIGRATION
DOI:10.1093/neuonc/noae064.336 -
Galban S. 2024 May 10;PresentationOffice of Faculty Affairs and Faculty Development Research Faculty Grant Orientation
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Galban S. 2024 Apr 30;PresentationRogel Cancer Center Basic Science Retreat: "The Role of the Tumor Microenvironment in Resistance to Oncogenic KRAS Inhibition in Lung Cancer"
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Waits S, Hughes T, Kemp S, Chang A, Galban S. 2024 Apr 16;PresentationPromotion Panel
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Galban S. 2024 Mar 19;PresentationConcurrent Inhibition of DNA-PK and homology-directed DNA repair for the treatment of Diffuse Intrinsic Pontine Glioma (DIPG/DMG-H3K27 altered)