Research Assistant Professor
Surgery
Cardiac Surgery
2800 Plymouth Rd
Ann Arbor, MI 48109-2800
[email protected]
2800 Plymouth Rd
Ann Arbor, MI 48109-2800
Available to mentor
Morgan D Salmon
Research Assistant Professor
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Postdoctoral Research AssociateUniversity of Virginia Health System, Department of Surgery, 2013
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Postdoctoral Research FellowUniversity of Virginia Health System, Charlottesville, 2012
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Center MemberSamuel and Jean Frankel Cardiovascular Center
Aortic aneurysms(AAAs) represent the 15th cause of death and currently have no medical treatment therapy. My interests include studying the roles of DNA and RNA epigenetic regulation of smooth muscle cells and macrophages in aortic aneurysm growth and rupture.
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Millar JK, Salmon M, Nasser E, Malik S, Kolli P, Lu G, Pinteaux E, Hawkins RB, Ailawadi G. J Thorac Cardiovasc Surg, 2024 May; 167 (5): e146 - e158.Journal ArticleEndothelial to mesenchymal transition in the interleukin-1 pathway during aortic aneurysm formation.
DOI:10.1016/j.jtcvs.2023.11.010 PMID: 37951532 -
Song J, Zhang Y, Frieler RA, Andren A, Wood S, Tyrrell DJ, Sajjakulnukit P, Deng JC, Lyssiotis CA, Mortensen RM, Salmon M, Goldstein DR. J Clin Invest, 2023 Dec 12; 134 (3):Journal ArticleItaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice.
DOI:10.1172/JCI173034 PMID: 38085578 -
Kazaleh M, Gioscia-Ryan R, Ailawadi G, Salmon M. Biomedicines, 2023 Dec 19; 12 (1):Journal ArticleOxidative Stress and the Pathogenesis of Aortic Aneurysms.
DOI:10.3390/biomedicines12010003 PMID: 38275364 -
Yodsanit N, Shirasu T, Huang Y, Yin L, Islam ZH, Gregg AC, Riccio AM, Tang R, Kent EW, Wang Y, Xie R, Zhao Y, Ye M, Zhu J, Huang Y, Hoyt N, Zhang M, Hossack JA, Salmon M, Kent KC, Guo L-W, Gong S, Wang B. Bioact Mater, 2023 Aug; 26: 52 - 63.Journal ArticleTargeted PERK inhibition with biomimetic nanoclusters confers preventative and interventional benefits to elastase-induced abdominal aortic aneurysms.
DOI:10.1016/j.bioactmat.2023.02.009 PMID: 36875050 -
Song J, Farris D, Ariza P, Moorjani S, Varghese M, Blin M, Chen J, Tyrrell D, Zhang M, Singer K, Salmon M, Goldstein DR. Aging Cell, 2023 Feb; 22 (2): e13783Journal ArticleAge-associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis.
DOI:10.1111/acel.13783 PMID: 36683460 -
Millar J, Nasser E, Ailawadi G, Salmon M. J Cell Immunol, 2023 5 (2): 22 - 31.Journal ArticleIL-1 in Abdominal Aortic Aneurysms.
DOI:10.33696/immunology.5.163 PMID: 37476160 -
Filiberto AC, Spinosa MD, Elder CT, Su G, Leroy V, Ladd Z, Lu G, Mehaffey JH, Salmon MD, Hawkins RB, Ravichandran KS, Isakson BE, Upchurch GR, Sharma AK. Nat Commun, 2022 Mar 21; 13 (1): 1521Journal ArticleEndothelial pannexin-1 channels modulate macrophage and smooth muscle cell activation in abdominal aortic aneurysm formation.
DOI:10.1038/s41467-022-29233-4 PMID: 35315432 -
Salmon M, Hawkins RB, Dahl J, Scott E, Johnston WF, Ailawadi G. Ann Vasc Surg, 2022 Sep; 85: 358 - 370.Journal ArticleGenetic and Pharmacological Disruption of Interleukin-1α Leads to Augmented Murine Aortic Aneurysm.
DOI:10.1016/j.avsg.2022.05.024 PMID: 35680012