Available to mentor
Dr. Beamish’s career in Nephrology was inspired by the remarkable ability of some patients to recover after severe kidney injury. The strongest motivator for his research is finding treatments that encourage recovery in more patients. The broad goal of Dr. Beamish’s laboratory is to discover new strategies to promote kidney regeneration using an approach that integrates both engineering and biological tools. Dr. Beamish completed a BS and PhD in Chemical and Biomedical Engineering, respectively, as well as clinical training in Internal Medicine and Nephrology. His expertise spans many disciplines, including biomaterials engineering, animal models of kidney injury and physiology, analysis of multimodal sequencing data, deep-learning image analysis, and the genetics and molecular biology of transcriptional regulation in kidney cells. His work has been supported by the American Heart Association, the American Society of Nephrology, and the NIH. In addition to his research activities, Dr. Beamish also directs the outpatient nephrology clinics at the VA Ann Arbor Healthcare System.
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Nephrology FellowshipUniversity of Michigan–Ann Arbor, Ann Arbor, 2016
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Internal Medicine ResidencyUniversity Hospitals Case Medical Center, Cleveland, 2014
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MD, PhDCase Western Reserve University, Cleveland, 2011
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BSNorthwestern University, Evanston, 2003
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Beamish JA, Watts JA, Dressler GR. J Biol Chem, 2024 Jun 29; 300 (8): 107520Journal ArticleGene regulation in regeneration after acute kidney injury.
DOI:10.1016/j.jbc.2024.107520 PMID: 38950862 -
Beamish J. 2024 Jun 4;PresentationThe functions of Pax8 as a master regulator of proximal tubule identity
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Friend NE, Beamish JA, Margolis EA, Schott NG, Stegemann JP, Putnam AJ. J Biomed Mater Res A, 2024 Apr; 112 (4): 549 - 561.Journal ArticlePre-cultured, cell-encapsulating fibrin microbeads for the vascularization of ischemic tissues.
DOI:10.1002/jbm.a.37580 PMID: 37326361 -
Soofi A, Li V, Beamish JA, Abdrabh S, Hamad M, Das NK, Shah YM, Dressler GR. Am J Physiol Renal Physiol, 2024 Feb 1; 326 (2): F178 - F188.Journal ArticleRenal-specific loss of ferroportin disrupts iron homeostasis and attenuates recovery from acute kidney injury.
DOI:10.1152/ajprenal.00184.2023 PMID: 37994409 -
McElliott MC, Al-Suraimi A, Telang AC, Ference-Salo JT, Chowdhury M, Soofi A, Dressler GR, Beamish JA. Sci Rep, 2023 Apr 19; 13 (1): 6361Journal ArticleHigh-throughput image analysis with deep learning captures heterogeneity and spatial relationships after kidney injury.
DOI:10.1038/s41598-023-33433-3 PMID: 37076596 -
McElliott MC, Telang AC, Otto EA, Soofi AA, Dressler GR, Beamish JA. Journal of the American Society of Nephrology, 2023 Nov; 34 (11S): 455 - 455.Journal ArticleLoss of Pax2 and Pax8 Induces Resistance to Ischemia in S3 Proximal Tubule
DOI:10.1681/asn.20233411s1455a -
Soofi AA, Li V, Beamish JA, Dressler GR. Journal of the American Society of Nephrology, 2023 Nov; 34 (11S): 118 - 119.Journal ArticleMouse Model of Local Iron Homeostasis Disruption in AKI
DOI:10.1681/asn.20233411s1118d -
Telang AC, McElliott MC, Ference-Salo JT, Beamish JA. Journal of the American Society of Nephrology, 2023 Nov; 34 (11S): 725 - 725.Journal ArticleRapid Loss of Proximal-Tubule-Specific Gene Expression in Primary Culture Associates with HNF4a Downregulation
DOI:10.1681/asn.20233411s1725c