Adam C Abraham
Research Investigator
Orthopaedic Surgery
Orthopaedic Surgery
109 Zina Pitcher
Ann Arbor, MI 48109
[email protected]

Available to mentor

Adam C Abraham
Research Investigator
  • Qualifications
  • Center Memberships
  • Research Overview
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  • Recent Publications
  • Qualifications
    • Postdoctoral Research Scientist
      Columbia University Medical Center, Orthopaedic Surgery, 2019
    • Postdoctoral Fellow
      Washington University in St. Louis School of Medicine, Orthopaedic Surgery, 2015
    • PhD
      Colorado State University, Fort Collins, 2013
    • MS
      Michigan Technological University, Houghton, 2008
    • BS
      Michigan Technological University, Houghton, 2006
    Center Memberships
    • Center Member
      Biosciences Initiative
    Research Overview

    My multi-disciplinary background spans the fields of mechanical and biomedical engineering with additional training in metabolic diseases and immunology. My research expertise includes multi-scale biomechanics, inflammation, and musculoskeletal disease modeling. My research is focused on:
    1. Musculoskeletal tissue pathophysiology and mechanics
    2. Exercise and overuse mechanobiology of connective soft tissues (e.g. tendons, ligaments, etc.)
    3. Engineering immune-stromal crosstalk during the inflammatory response

    • Department Profile
    Recent Publications See All Publications
    • Preprint
      Nuclear Factor Kappa B Over-Activation in the Intervertebral Disc Leads to Macrophage Recruitment and Severe Disc Degeneration.
      Burt KG, Kim MKM, Viola DC, Abraham AC, Chahine NO. 2023 Aug 8; DOI:10.1101/2023.08.07.552274
      PMID: 37609194
    • Journal Article
      Optogenetic-induced muscle loading leads to mechanical adaptation of the Achilles tendon enthesis in mice.
      Ganji E, Lamia SN, Stepanovich M, Whyte N, Goulet RW, Abraham AC, Killian ML. Sci Adv, 2023 Jun 23; 9 (25): eadf4683 DOI:10.1126/sciadv.adf4683
      PMID: 37352350
    • Journal Article
      Optogenetic-Induced Muscle Loading Leads to Mechanical Adaptation of the Achilles Tendon Enthesis in Mice.
      Ganji E, Lamia SN, Stepanovich M, Whyte N, Abraham AC, Killian ML. bioRxiv, 2023 May 2; DOI:10.1101/2023.04.11.536376
      PMID: 37090593
    • Journal Article
      Comparison of Distal Spine Anchors and Distal Pelvic Anchors in Children With Hypotonic Neuromuscular Scoliosis Treated With Growth-friendly Instrumentation.
      Ahmady A, Rosenthal L, Abraham AC, Parker B, Brooks JT, Cahill PJ, Smith JT, Sponseller PD, Sturm PF, Li Y, Pediatric Spine Study Group . J Pediatr Orthop, 2023 May; 43 (5): e319 - e325. DOI:10.1097/BPO.0000000000002376
      PMID: 36827606
    • Journal Article
      Physical and Soluble Cues Enhance Tendon Progenitor Cell Invasion into Injectable Synthetic Hydrogels
      Kent RN, Said M, Busch ME, Poupard ER, Tsai A, Xia J, Matera DL, Wang WY, DePalma SJ, Hiraki HL, Killian ML, Abraham AC, Shin JW, Huang AH, Shikanov A, Baker BM. Advanced Functional Materials, 2022 Nov 24; 32 (48): DOI:10.1002/adfm.202207556
    • Journal Article
      Tendon progenitor cells as biological augmentation improve functional gait and reduce scar formation after rotator cuff repair.
      Vervaecke AJ, Carbone AD, Abraham A, Bernstein Z, Laudier D, Verborgt O, Galatz LM, Huang AH. J Shoulder Elbow Surg, 2022 Nov; 31 (11): 2366 - 2380. DOI:10.1016/j.jse.2022.05.004
      PMID: 35671924
    • Journal Article
      The role of loading in murine models of rotator cuff disease.
      Abraham AC, Fang F, Golman M, Oikonomou P, Thomopoulos S. J Orthop Res, 2022 Apr; 40 (4): 977 - 986. DOI:10.1002/jor.25113
      PMID: 34081350
    • Preprint
      The role of TGFβ signaling in Gli1+ tendon and enthesis cells
      Song L, Golman M, Abraham A, Zelzer E, Thomopoulos S. 2022 bioRxiv, DOI:10.1101/2022.03.03.482926