Available to mentor
Chelsea Kaplan is a Research Assistant Professor in the Department of Anesthesiology and the Director of Neuroimaging in the Chronic Pain and Fatigue Research Center (CPFRC). She completed her undergraduate degree in Brain, Behavior and Cognitive Science and received her doctorate in Neuroscience from the University of Michigan in 2018. Her graduate and postdoctoral training was completed at the CPFRC where she focused on examining the neurobiology of chronic pain using multimodal imaging techniques. Dr. Kaplan’s research includes investigating the central nervous system contributions to nociplastic pain across many conditions, identifying biomarkers that predict treatment outcomes, and examining the neural correlates of inflammation in rheumatic disease and nociplastic pain conditions. Her most recent work is focused on investigating behavioral and neurobiological factors associated with the development and trajectory of chronic pain in children. Understanding the neural vulnerability to pain may provide new insights about pain mechanisms, with the hope that identifying at-risk youth will enable early interventions that may alter the lifelong course of chronic pain.
Chronic Pain & Fatigue Research Center
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Research FellowUniversity of Michigan–Ann Arbor, T32, 2022
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Postdoctoral ResearcherUniversity of Michigan, USA, 2022
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PhDUniversity of Michigan, 2018
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Center MemberMExperts-Opioid Research Institute
• The neurobiological mechanisms underlying the development of chronic pain during childhood and adolescence
• Identification of central nervous system biomarkers in nociplastic/centralized pain
• The relationship between peripheral inflammation and brain function
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Sunzini F, Stefanov K, Al-Wasity S, Kaplan C, Schrepf A, Waller N, Harte S, Harris R, Clauw DJ, McLean J, Siebert S, Goodyear CS, Waiter GD, Basu N. Arthritis Research and Therapy, 2025 Dec 1; 27 (1):Journal ArticleThe insula represents a key neurobiological pain hub in psoriatic arthritis
DOI:10.1186/s13075-025-03526-7 PMID: 40165287 -
Portengen C, Smith T, Hidalgo-Lopez E, Becker H, Lenert M, Schrepf A, Harte S, Kaplan C, Beltz A. 2025 Jun 15;Proceeding / Abstract / PosterEarly Pubertal Timing is a Risk Factor for Adolescent Dysmenorrhea
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Hidalgo-Lopez E, Smith T, Portengen C, Becker H, Beltz A, Kaplan C. 2025 Jun 15;Proceeding / Abstract / PosterSex and Puberty-Related Brain Structure Differences in Youth With and Without Multisite
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De Lott LB, Kaplan C, Harte S, Clauw DJ, Galor A, Vehof J, Shtein RM. Survey of Ophthalmology, 2025 May 1; 70 (3): 536 - 543.Journal ArticleNociplastic pain among individuals with chronic ocular surface pain: One cause for “pain without stain”?
DOI:10.1016/j.survophthal.2025.01.004 PMID: 39814104 -
Mauck MC, Barth KS, Bell KM, Brooks AK, Chadwick AL, Gunn CA, Hurley RW, Ivanova A, Piva SR, Schneider MJ, Bailey JF, Bagaason S, Batorsky A, Borckardt JJ, Bowden AE, Carey TS, Castellanos J, Chen L, Chidgey B, Dalton D, Dufour JS, Fields AJ, Fritz JM, Goolsby RW, Greco CM, Harris RE, Harte S, Hassett AL, Hoffmeyer A, Jones Berkeley S, Kaplan C, Kidwell KM, Knapik GG, Kosorok MR, Kurillo G, Lobo R, Lotz JC, Mackey S, Mageswaran P, Majumdar S, Mao J, Marras WS, McCumber M, McLean SA, Mehling W, Mitchell UH, Napadow VJ, O'Neill C, Patel KV, Peltier S, Psioda M, Rowland B, Rundell SD, Schrepf A, Sperger J, Vo N, Wallace MS, Wasan AD, Weaver TE, Weber KA, Williams DA, Wilson L, Zeidan F, Zhao B, Anstrom KJ, Clauw DJ, Sowa GA. Pain Med, 2025 Apr 9;Journal ArticleThe Design and Rationale of the Biomarkers for Evaluating Spine Treatments (BEST) Trial: A Sequential Multiple Assignment Randomized Trial.
DOI:10.1093/pm/pnaf032 PMID: 40205455 -
Hidalgo-Lopez E, Beltz AM, Lenert ME, Harte S, Schrepf A, Kaplan CM. 2025 Apr 29;Proceeding / Abstract / PosterIndividualized Neural Networks Differ Based on Depressive Symptoms in Women with Urologic Chronic Pelvic Pain Syndrome
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Evanski JM, Kaplan C, Harte SE. 2025 Apr 29;Proceeding / Abstract / PosterSex Differences in Endocannabinoid Levels And Associations With Pain Risk Factors In Adolescents
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Hidalgo-Lopez E, Smith T, Angstadt M, Becker HC, Schrepf A, Clauw DJ, Harte SE, Heitzeg MM, Mindell JA, Kaplan CM, Beltz AM. JAMA Netw Open, 2025 Apr 1; 8 (4): e255364Journal ArticleSex, Neural Networks, and Behavioral Symptoms Among Adolescents With Multisite Pain.
DOI:10.1001/jamanetworkopen.2025.5364 PMID: 40238096
