Chelsea Kaplan, PhD
Research Assistant Professor
Anesthesiology
[email protected]

Available to mentor

Chelsea Kaplan, PhD
Research Assistant Professor
  • About
  • Links
  • Qualifications
  • Research Overview
  • Recent Publications
  • About

    Chelsea Kaplan is a Research Assistant Professor in the Department of Anesthesiology and the Director of Neuroimaging in the Chronic Pain and Fatigue Research Center (CPFRC). She completed her undergraduate degree in Brain, Behavior and Cognitive Science and received her doctorate in Neuroscience from the University of Michigan in 2018. Her graduate and postdoctoral training was completed at the CPFRC where she focused on examining the neurobiology of chronic pain using multimodal imaging techniques. Dr. Kaplan’s research includes investigating the central nervous system contributions to nociplastic pain across many conditions, identifying biomarkers that predict treatment outcomes, and examining the neural correlates of inflammation in rheumatic disease and nociplastic pain conditions. Her most recent work is focused on investigating behavioral and neurobiological factors associated with the development and trajectory of chronic pain in children. Understanding the neural vulnerability to pain may provide new insights about pain mechanisms, with the hope that identifying at-risk youth will enable early interventions that may alter the lifelong course of chronic pain.

    Links
    • Chronic Pain & Fatigue Research Center
    Qualifications
    • PhD
      University of Michigan, Ann Arbor, 2018
    Research Overview

    • The neurobiological mechanisms underlying the development of chronic pain during childhood and adolescence
    • Identification of central nervous system biomarkers in nociplastic/centralized pain
    • The relationship between peripheral inflammation and brain function

    Recent Publications See All Publications
    • Journal Article
      Deciphering nociplastic pain: clinical features, risk factors and potential mechanisms.
      Kaplan CM, Kelleher E, Irani A, Schrepf A, Clauw DJ, Harte SE. Nat Rev Neurol, 2024 Jun; 20 (6): 347 - 363. DOI:10.1038/s41582-024-00966-8
      PMID: 38755449
    • Proceeding / Abstract / Poster
      Adverse Childhood Experiences and Multisite Pain Among Children in the United States
      Kheirabadi D, Smith T, Guo Y, Sun J, Pierce J, Bergmans R, Boehnke K, Schrepf A, Clauw D, Kaplan CC, Arewasikporn A. Journal of Pain, 2024 Apr; 25 (4): 53 DOI:10.1016/j.jpain.2024.01.244
    • Journal Article
      Broadening the Scope of Resilience in Chronic Pain: Methods, Social Context, and Development.
      Sturgeon JA, Zubieta C, Kaplan CM, Pierce J, Arewasikporn A, Slepian PM, Hassett AL, Trost Z. Curr Rheumatol Rep, 2024 Apr; 26 (4): 112 - 123. DOI:10.1007/s11926-024-01133-0
      PMID: 38270842
    • Proceeding / Abstract / Poster
      Resting State Connectivity Networks Underpinning Multisite Pain in Adolescent Girls and Boys
      Hidalgo-Lopez E, Smith T, Becker H, Angstadt M, Schrepf A, Williams DA, Clauw D, Harte SE, Kaplan C, Beltz A. Journal of Pain, 2024 Apr; 25 (4): 48 - 49. DOI:10.1016/j.jpain.2024.01.225
    • Proceeding / Abstract / Poster
      Sex Differences in Pain-Related Central Nervous System-Mediated Symptom Clusters in Children with Multisite Pain
      Smith T, Hidalgo-Lopez E, Becker H, Schrepf A, Williams DA, Clauw D, Harte SE, Mindell JA, Beltz A, Kaplan C. Journal of Pain, 2024 Apr; 25 (4): 67 DOI:10.1016/j.jpain.2024.01.307
    • Proceeding / Abstract / Poster
      Sex Differences in Pain-Related Central Nervous System-Mediated Symptom Clusters in Children with Multisite Pain
      Smith T, Hidalgo-Lopez E, Becker H, Schrepf A, Williams DA, Clauw D, Harte SE, Mindell JA, Beltz A, Kaplan C. Journal of Pain, 2024 Apr; 25 (4): 67 DOI:10.1016/j.jpain.2024.01.307
    • Proceeding / Abstract / Poster
      Visual Quantitative Sensory Testing Provides Transdiagnostic Window into Behavioral and Functional Neural Correlates of Nociplastic Pain
      Waller N, Kaplan C, Schrepf A, Ichesco E, Harris R, Clauw D, Harte S. Journal of Pain, 2024 Apr; 25 (4): 49 - 50. DOI:10.1016/j.jpain.2024.01.229
    • Proceeding / Abstract / Poster
      9.9 A preliminary comparison of brain morphometry between youth American football and non-football athletes: a report using adolescent brain cognitive development (ABCD) study data
      Eckner J, Ichesco E, Li Y, Ichesco I, Schrepf A, Alsalaheen B, Almeida A, Lorincz M, Kaplan C, Popovich M, Peltier S, Harris R, He X, Eckner J. 2024 Jan; a47.1 - a4a47. DOI:10.1136/bjsports-2023-concussion.125
    Featured News & Stories Nociplastic pain researchers Chelsea Kaplan, Steven Harte, Andrew Schrepf, Dan Clauw
    Department News
    What we know about nociplastic pain
    A new review article shines light on nociplastic pain, a type of pain some thought to be ‘all in your head’
    Department News
    Fourteen faculty promotions announced
    The University of Michigan Regents approved 14 Department of Anesthesiology faculty promotions during their May 2023 meeting. Promotions will go into effect September 1.