Lana Garmire, PhD
Associate Professor of Computational Medicine and Bioinformatics
Associate Professor of Biostatistics
[email protected]

Available to mentor

Lana Garmire, PhD
Associate Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    I'm a nationally and internationally recognized expert in translational and biomedical informatics. I obtained the MA degree in Statistics (2005) and PhD degree in Comparative Biochemistry (Computational Biology focus, 2007), both from UC-Berkeley. I started the first tenure-track faculty position in University of Hawaii Cancer Center later 2012 and was promoted to Associate Professor with tenure in 2017. I moved to University of Michigan in 2018 to expand the research to multi-modal research (genomics, EMR and pathological imaging analysis). I published over 100 papers in top quality journals including Cell, Nature Communications, Genome Biology, Genome Medicine, Clinical Cancer Research. I contributed as the senior corresponding author in the majority of these publications. I delivered over 90 invited talks to institutes including National Library of Medicine (NLM) and National Academy of Sciences (NAS). I have mentored over 90 Assistant Professors, MD fellows, postdocs, graduate students and undergraduates of various academic backgrounds, in Biology, Mathematics, Physics, (bio)Statistics, Bioengineering, Computer Science and Electrical Engineering. Most PhD and postdoc trainees became faculty or senior scientists in private sectors. I served on various NIH study sections and currently am a standing member of BDMA study section. I am on the editorial advisory board for journals Genome Biology and Journal of Proteome Research. Among the awards, the noticeable ones include US Presidential Early Career Scientists and Engineers in 2019, and fellowship of American Institute of Medical and Biological Engineering (AIMBE) since 2022.

    Links
    • Garmire Group
    Qualifications
    • Postdoctoral Fellow
      University of California, San Diego, Bioengineering, 2011
    • PhD
      University of California, Berkeley, Berkeley, 2007
    • MA
      University of California, Berkeley, Berkeley, 2005
    • BS
      Ocean University of China, Qingdao, 2001
    Center Memberships
    • Center Member
      Rogel Cancer Center
    • Center Member
      Precision Health Initiative
    • Center Member
      e-Health and Artificial Intelligence Initiative
    Research Overview

    My research interest lies in applying data science for actionable transformation of human health from the bench to bedside. Current research focus areas include cutting edge single-cell sequencing informatics and genomics; precision medicine through integration of multi-omics data types; novel modeling and computational methods for biomarker research; public health genomics. I apply my biomedical informatics and analytical expertise to study diseases such as cancers, and neonatal/women's health.

    Recent Publications See All Publications
    • Preprint
      Originator: Computational Framework Separating Single-Cell RNA-Seq by Genetic and Contextual Information.
      Unjitwattana T, Huang Q, Du Y, Yang Y, Zhou M, Garmire LX. 2024 Apr 6; DOI:10.1101/2024.04.04.588144
      PMID: 38617220
    • Journal Article
      Antigen-Clustered Nanovaccine Achieves Long-Term Tumor Remission by Promoting B/CD 4 T Cell Crosstalk.
      Li C, Clauson R, Bugada LF, Ke F, He B, Yu Z, Chen H, Jacobovitz B, Hu H, Chuikov P, Hill BD, Rizvi SM, Song Y, Sun K, Axenov P, Huynh D, Wang X, Garmire L, Lei YL, Grigorova I, Wen F, Cascalho M, Gao W, Sun D. ACS Nano, 2024 Apr 2; 18 (13): 9584 - 9604. DOI:10.1021/acsnano.3c13038
      PMID: 38513119
    • Preprint
      Discover overlooked complications after preeclampsia using electronic health records.
      Garmire L, Zhu H, Yangs X, Xie W, Langen E, Li R. 2024 Mar 6; DOI:10.21203/rs.3.rs-3937688/v1
      PMID: 38496631
    • Journal Article
      Challenges and perspectives in computational deconvolution of genomics data.
      Garmire LX, Li Y, Huang Q, Xu C, Teichmann SA, Kaminski N, Pellegrini M, Nguyen Q, Teschendorff AE. Nat Methods, 2024 Mar; 21 (3): 391 - 400. DOI:10.1038/s41592-023-02166-6
      PMID: 38374264
    • Journal Article
      Deep learning and transfer learning identify breast cancer survival subtypes from single-cell imaging data.
      Yadav S, Zhou S, He B, Du Y, Garmire LX. Commun Med (Lond), 2023 Dec 19; 3 (1): 187 DOI:10.1038/s43856-023-00414-6
      PMID: 38114659
    • Preprint
      Perceptual and technical barriers in sharing and formatting metadata accompanying omics studies
      Huang Y-N, Love MI, Ronkowski CF, Deshpande D, Schriml LM, Wong-Beringer A, Mons B, Corbett-Detig R, Hunter CI, Moore JH, Garmire LX, Reddy TBK, Hide WA, Butte AJ, Robinson MD, Mangul S. 2023 Nov 22; arXiv, DOI:10.48550/arxiv.2401.02965
    • Journal Article
      Characterization of long COVID temporal sub-phenotypes by distributed representation learning from electronic health record data: a cohort study.
      Dagliati A, Strasser ZH, Hossein Abad ZS, Klann JG, Wagholikar KB, Mesa R, Visweswaran S, Morris M, Luo Y, Henderson DW, Samayamuthu MJ, Tan BWQ, Verdy G, Omenn GS, Xia Z, Bellazzi R, Consortium for Clinical Characterization of COVID-19 by EHR (4CE), , Murphy SN, Holmes JH, Estiri H, Consortium for Clinical Characterization of COVID-19 by EHR (4CE) . EClinicalMedicine, 2023 Oct; 64: 102210 DOI:10.1016/j.eclinm.2023.102210
      PMID: 37745021
    • Journal Article
      Clinical phenotypes and outcomes in children with multisystem inflammatory syndrome across SARS-CoV-2 variant eras: a multinational study from the 4CE consortium.
      Sperotto F, Gutiérrez-Sacristán A, Makwana S, Li X, Rofeberg VN, Cai T, Bourgeois FT, Omenn GS, Hanauer DA, Sáez C, Bonzel C-L, Bucholz E, Dionne A, Elias MD, García-Barrio N, González TG, Issitt RW, Kernan KF, Laird-Gion J, Maidlow SE, Mandl KD, Ahooyi TM, Moraleda C, Morris M, Moshal KL, Pedrera-Jiménez M, Shah MA, South AM, Spiridou A, Taylor DM, Verdy G, Visweswaran S, Wang X, Xia Z, Zachariasse JM, Consortium for Clinical Characterization of COVID-19 by EHR (4CE) , Newburger JW, Avillach P. EClinicalMedicine, 2023 Oct; 64: 102212 DOI:10.1016/j.eclinm.2023.102212
      PMID: 37745025