Available to mentor
I'm a nationally and internationally recognized expert in translational and biomedical informatics. I obtained the MA degree in Statistics (2005) and PhD degree in Comparative Biochemistry (Computational Biology focus, 2007), both from UC-Berkeley. I started the first tenure-track faculty position in University of Hawaii Cancer Center later 2012 and was promoted to Associate Professor with tenure in 2017. I moved to University of Michigan in 2018 to expand the research to multi-modal research (genomics, EMR and pathological imaging analysis). I published over 100 papers in top quality journals including Cell, Nature Communications, Genome Biology, Genome Medicine, Clinical Cancer Research. I contributed as the senior corresponding author in the majority of these publications. I delivered over 90 invited talks to institutes including National Library of Medicine (NLM) and National Academy of Sciences (NAS). I have mentored over 90 Assistant Professors, MD fellows, postdocs, graduate students and undergraduates of various academic backgrounds, in Biology, Mathematics, Physics, (bio)Statistics, Bioengineering, Computer Science and Electrical Engineering. Most PhD and postdoc trainees became faculty or senior scientists in private sectors. I served on various NIH study sections and currently am a standing member of BDMA study section. I am on the editorial advisory board for journals Genome Biology and Journal of Proteome Research. Among the awards, the noticeable ones include US Presidential Early Career Scientists and Engineers in 2019, and fellowship of American Institute of Medical and Biological Engineering (AIMBE) since 2022.
Garmire Group
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Postdoctoral FellowUniversity of California, San Diego, Bioengineering, 2011
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PhDUniversity of California, Berkeley, Berkeley, 2007
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MAUniversity of California, Berkeley, Berkeley, 2005
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BSOcean University of China, Qingdao, 2001
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Center MemberRogel Cancer Center
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Center MemberInstitute for Healthcare Policy and Innovation
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Center MemberPrecision Health Initiative
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Center Membere-Health and Artificial Intelligence Initiative
My research interest lies in applying data science for actionable transformation of human health from the bench to bedside. Current research focus areas include cutting edge single-cell sequencing informatics and genomics; precision medicine through integration of multi-omics data types; novel modeling and computational methods for biomarker research; public health genomics. I apply my biomedical informatics and analytical expertise to study diseases such as cancers, and neonatal/women's health.
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Zhu H, Yang X, Tao L, Xie W, Chang J-H, Wang ZP, Langen E, Li R, Gamire LX. 2024 Nov 2;PreprintDiscover overlooked complications after preeclampsia from three real-world medical record datasets of over 100,000 pregnancies.
DOI:10.1101/2023.12.05.23299296 PMID: 38405849 -
Li Y, Stanojevic S, He B, Jing Z, Huang Q, Kang J, Garmire LX. Res Sq, 2024 Oct 25;Journal ArticleAdding Highly Variable Genes to Spatially Variable Genes Can Improve Cell Type Clustering Performance in Spatial Transcriptomics Data.
DOI:10.21203/rs.3.rs-5315913/v1 PMID: 39502778 -
Li Y, Choi KS, Dunlop BW, Craighead WE, Mayberg HS, Garmire L, Guo Y, Kang J. 2024 Oct 3; arXiv,PreprintBSNMani: Bayesian Scalar-on-network Regression with Manifold Learning
DOI:10.48550/arxiv.2410.02965 -
Zahiri J, Mirzaie M, Duan K, Xiao Y, Aamodt C, Yang X, Nazari S, Andreason C, Lopez L, Barnes CC, Arias S, Nalabolu S, Garmire L, Wang T, Hoekzema K, Eichler EE, Pierce K, Lewis NE, Courchesne E. 2024 Sep 23;PreprintBeyond the Spectrum: Subtype-Specific Molecular Insights into Autism Spectrum Disorder Via Multimodal Data Integration.
DOI:10.1101/2024.09.17.24313857 PMID: 39399028 -
Du Y, Benny PA, Shao Y, Schlueter RJ, Gurary A, Lum-Jones A, Lassiter CB, AlAkwaa FM, Tiirikainen M, Towner D, Ward WS, Garmire LX. 2024 Aug 13;PreprintMulti-omics Analysis of Umbilical Cord Hematopoietic Stem Cells from a Multi-ethnic Cohort of Hawaii Reveals the Transgenerational Effect of Maternal Pre-Pregnancy Obesity.
DOI:10.1101/2024.07.27.24310936 PMID: 39108521 -
Chopra H, Cao C, Alice H, Kak S, Maska B, Tagett R, Sugai J, Garmire L, Kaigler D. 2024 Aug 3;PreprintLandscape of Differentiation Potentials as a "Hallmark" in Oral-derived MSCs.
DOI:10.1101/2024.08.02.606413 PMID: 39211139 -
Garmire L. 2024 Jul 10;PresentationUtilize the Cellular Heterogeneity at the Single Cell Level for Cancer Treatment and Survival Prediction
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Garmire L. 2024 Jun 14;Presentationsingle-cell and spatial transcriptomics-based cancer drug and progression prediction