Research Investigator
Biological Chemistry
[email protected]
Available to mentor
Kevin Bohannon, PhD
Research Investigator
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Postdoctoral FellowUniversity of Michigan, Pharmacology, 2019
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PhD in VirologyNorthwestern University, Chicago, IL, 2013
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B.S. in BiologyIndiana University, Bloomington, IN, 2006
ESCRT proteins are recruited to disrupted membranes, where they promote repair and resilience. I am interested in determining the specific molecular patterns that trigger ESCRT recruitment.
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Chen W, Motsinger MM, Li J, Bohannon KP, Hanson PI. Proc Natl Acad Sci U S A, 2024 May 28; 121 (22): e2318412121Journal ArticleCa2+-sensor ALG-2 engages ESCRTs to enhance lysosomal membrane resilience to osmotic stress.
DOI:10.1073/pnas.2318412121 PMID: 38781205 -
Bohannon KP, Hanson PI. Curr Opin Cell Biol, 2020 Aug; 65: 122 - 130.Journal ArticleESCRT puts its thumb on the nanoscale: Fixing tiny holes in endolysosomes.
DOI:10.1016/j.ceb.2020.06.002 PMID: 32731154 -
Abbineni PS, Bohannon KP, Bittner MA, Axelrod D, Holz RW. Biophysical Journal, 2018 Feb; 114 (3): 284aProceeding / Abstract / PosterSecretory Granule Lumenal Proteins Have Highly Limited Mobility
DOI:10.1016/j.bpj.2017.11.1632 -
Bendahmane M, Bohannon KP, Rao TC, Michael SW, Abbineni P, Ranski AH, Bradberry MM, Tran S, Chon NL, Knight JD, Lin H, Chapman ER, Anantharam A. Biophysical Journal, 2018 Feb; 114 (3): 282aProceeding / Abstract / PosterThe Synaptotagmin Calcium-Binding Loops Modulate the Rate of Fusion Pore Expansion
DOI:10.1016/j.bpj.2017.11.1623 -
Bittner MA, Bohannon KP, Axelrod D, Holz RW. bioRxiv,PreprintIdentification of β-synuclein on secretory granules in chromaffin cells and the effects of α-and β-synuclein on BDNF discharge following fusion
DOI:10.1101/158220 -
Abbineni PS, Bohannon KP, Bittner MA, Axelrod D, Holz RW. Biophysical Journal, 2017 Feb; 112 (3): 472aProceeding / Abstract / PosterMeasurement of the Mobility of Lumenal and Membrane Proteins of Individual Secretory Granules
DOI:10.1016/j.bpj.2016.11.2533 -
2016 Oct 1;PresentationHow could a DNA vaccine stop the Zika virus?
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2016 Aug 1;PresentationPhysiological Implications of Slow Fusion Pore Expansion on Protein Discharge
Department News
Kevin Bohannon, PhD, named Research Scout for Michigan Medicine funding program