Dale Litzenberg, PhD
Clinical Professor of Radiation Oncology
Radiation Oncology
1500 E Medical Center Dr
Ann Arbor, MI 48109
[email protected]

Available to mentor

Dale Litzenberg, PhD
Clinical Professor
  • About
  • Links
  • Qualifications
  • Research Overview
  • Recent Publications
  • About

    Dr. Litzenberg joined the Department of Radiation Oncology in 1997 after completing his PhD in Physics at the University of Michigan. He completed his post-doctoral training in the department and joined the faculty in 2002. His primary research interests include FLASH radiation therapy using ultra high dose rates to reduce toxicity to healthy tissues, and the implementation and integration of new technologies. He was the first to implement and fully integrate a six degree of freedom patient-positioning system with daily image guidance for targeting moving tumors. He was an early pioneer in studying the effect of magnetic fields on radiation therapy beams, and also of real-time electromagnetic tracking of moving tumors.

    Dr. Litzenberg is currently spending half his time at our new clinic in Brighton. Several features on the newest treatment machines were invented or inspired by his previous clinical research and are now being implemented into routine clinical use to improve treatment accuracy.

    Links
    • RadOnc Bio
    Qualifications
    • PhD
      University of Michigan, Ann Arbor, 1997
    • MS
      University of Michigan, Ann Arbor, 1992
    • BS
      Purdue University, West Lafayette, 1990
    Research Overview

    - "FLASH Radiation Therapy": This emerging therapy with extremely high dose rates consumes intracellular oxygen inducing a protective hypoxic state in normal tissues to reduce toxicity while maintaining efficacy
    - "Precision Treatment of Prostate Cancer": Development and implementation of novel targeting and motion management techniques and technology, and clinical trials to improve quality of life.
    - Stereotactic brain radiosurgery
    - Total body irradiation
    - Electromagnetic tracking for real-time targeting of prostate and liver tumors
    - Quality assurance

    Recent Publications See All Publications
    • Journal Article
      A prototype scintillator real-time beam monitor for ultra-high dose rate radiotherapy.
      Levin DS, Friedman PS, Ferretti C, Ristow N, Tecchio M, Litzenberg DW, Bashkirov V, Schulte R. Med Phys, 2024 Apr; 51 (4): 2905 - 2923. DOI:10.1002/mp.17018
      PMID: 38456622
    • Proceeding / Abstract / Poster
      Contemporary androgen deprivation therapy practice patterns in locally advanced prostate cancer treated with definitive radiotherapy: Prospective results from a statewide radiation oncology quality consortium.
      Dykstra M, Regan S, Yin H, McLaughlin P, Boike TP, Bhatt A, Zaki MA, Kendrick D, Mislmani M, Paluch S, Litzenberg D, Mietzel MA, Narayana V, Smith A, Heimburger DK, Schipper MJ, Jackson WC, Dess RT. Journal of Clinical Oncology, 2024 Feb 1; 42 (4_suppl): 307 - 307. DOI:10.1200/jco.2024.42.4_suppl.307
    • Proceeding / Abstract / Poster
      Microboost dose escalation for localized prostate cancer within a statewide radiation oncology quality consortium.
      Regan S, Dykstra M, Yin H, McLaughlin P, Bhatt A, Boike TP, Walker EM, Zaki MA, Kendrick R, Mislmani M, Paluch S, Litzenberg D, Mietzel MA, Narayana V, Smith A, Heimburger DK, Schipper MJ, Jackson WC, Dess RT. Journal of Clinical Oncology, 2024 Feb 1; 42 (4_suppl): 298 - 298. DOI:10.1200/jco.2024.42.4_suppl.298
    • Proceeding / Abstract / Poster
      The development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient during radiation therapy
      Zhang W, Litzenberg D, Huang Y, Chang KW, Oraiqat I, Hadley S, Moros EG, Zhang M, Carson PL, Cuneo KC, El Naqa I, Wang X. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 2024 Jan 1; 12842: DOI:10.1117/12.3000346
    • Journal Article
      Variation in Androgen Deprivation Therapy Use Among Men With Intermediate-Risk Prostate Cancer: Results From a Statewide Radiation Oncology Quality Consortium.
      Dykstra MP, Regan SN, Yin HM, McLaughlin PW, Boike T, Bhatt A, Zaki M, Kendrick D, Mislmani M, Paluch S, Litzenberg DW, Mietzel MA, Narayana V, Smith A, Heimburger DK, Schipper MJ, Jackson WC, Dess RT, Michigan Radiation Oncology Quality Consortium . Int J Radiat Oncol Biol Phys, 2024 Jun 4; DOI:10.1016/j.ijrobp.2024.05.026
      PMID: 38844140
    • Proceeding / Abstract / Poster
      ADT Use and Nodal Irradiation in Men Receiving Post-Prostatectomy Salvage Radiotherapy within a Statewide Radiation Oncology Quality Consortium.
      Regan SN, Dykstra MP, Yin H, McLaughlin PW, Boike TP, Bhatt AK, Walker EM, Zaki M, Kendrick D, Mislmani M, Paluch S, Litzenberg DW, Mietzel M, Narayana V, Smith A, Jackson WC, Heimburger DK, Schipper M, Dess RT. Int J Radiat Oncol Biol Phys, 2023 Oct 1; 117 (2S): e430 - e431. DOI:10.1016/j.ijrobp.2023.06.1596
      PMID: 37785407
    • Proceeding / Abstract / Poster
      Androgen Deprivation Therapy Use among Intermediate Risk Prostate Cancer Patients Undergoing Radiation Therapy across a Statewide Radiation Oncology Quality Consortium.
      Dykstra MP, Regan SN, Yin H, McLaughlin PW, Boike TP, Bhatt AK, Walker EM, Zaki M, Kendrick D, Mislmani M, Paluch S, Litzenberg DW, Mietzel M, Narayana V, Smith A, Jackson WC, Heimburger DK, Schipper M, Dess RT. Int J Radiat Oncol Biol Phys, 2023 Oct 1; 117 (2S): e380 - e381. DOI:10.1016/j.ijrobp.2023.06.2491
      PMID: 37785288
    • Journal Article
      Real-time, volumetric imaging of radiation dose delivery deep into the liver during cancer treatment.
      Zhang W, Oraiqat I, Litzenberg D, Chang K-W, Hadley S, Sunbul NB, Matuszak MM, Tichacek CJ, Moros EG, Carson PL, Cuneo KC, Wang X, El Naqa I. Nat Biotechnol, 2023 Aug; 41 (8): 1160 - 1167. DOI:10.1038/s41587-022-01593-8
      PMID: 36593414