Roman Giger, PhD
Dr Richard Mark Newman Research Professor of Cell and Developmental Biology
Professor of Cell and Developmental Biology
Professor of Neurology
Medical School
[email protected]

Available to mentor
Roman Giger, PhD
Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications
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    Qualifications
    • Postdoctoral fellow
      Johns Hopkins University School of Medicine, Neuroscience, 2001
    • postdoctoral fellow
      Netherlands Institute for Neuroscience, Amsterdam, 1997
    • PhD
      University of Zurich, 1995
    • MS
      University of Zurich, 1991
    • BS
      University of Zurich, 1990
    Center Memberships
    • Center Member
      Center for Cell Plasticity and Organ Design
    • Center Member
      Biosciences Initiative
    Research Overview

    Nervous system regeneration, sciatic nerve, optic nerve, axon growth, neuroinflammation, axon-glia interaction, myelination, mouse genetics

    Links
    • Giger Lab
    Recent Publications See All Publications
    • Journal Article
      AxoMetric: A Rapid and Unbiased Tool for Automated Quantification of Axon Regeneration in Tissue Sections.
      Finneran MC, Rhamani T, Salioski IV, Schmitd LB, Passino R, Johnson CN, Giger RJ. bioRxiv, 2025 Jul 3; DOI:10.1101/2025.07.02.662816
      PMID: PMC12236587
    • Presentation
      Protecting the Inflamed Vasculature to Enhance Immune-Mediated Retinal Ganglion Cell Regeneration
      Giger, Ph.D. RJ. 2025 Jul 17;
    • Preprint
      Neurons maintain sequential order during radial migration by DSCAM-facilitated antagonism of N-Cadherin
      Yang T, Hergenreder T, Veling MW, Wang Y, Fuerst PG, Giger RJ, Zhao X-F. 2025 Jun 20; bioRxiv, DOI:10.1101/2025.06.16.659927
    • Presentation
      Advances in singe cell sequencing of injured mammalian PNS tissue
      Giger, Ph.D. RJ. 2025 Jul 17;
    • Journal Article
      Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature.
      Childs CJ, Poling HM, Chen K, Tsai Y-H, Wu A, Vallie A, Eiken MK, Huang S, Sweet CW, Schreiner R, Xiao Z, Spencer RC, Paris SA, Conchola AS, Villanueva JW, Anderman MF, Holloway EM, Singh A, Giger RJ, Mahe MM, Loebel C, Helmrath MA, Walton KD, Rafii S, Spence JR. Cell Stem Cell, 2025 Mar 21; S1934 - 5909. DOI:10.1016/j.stem.2025.02.007
    • Preprint
      Assigning Targetable Molecular Pathways to Transdiagnostic Subgroups Across Autism and Related Neurodevelopmental Disorders
      Ellegood J, Beauchamp A, Yee YC, Devenyi GA, Ziolkowski J, Qiu LR, Askalan R, Ayub M, Suetterlin P, Donovan APA, Pérez-Sisqués L, Basson A, Quesnel K, Berube N, Woo T, Beversdorf D, Bjornsson H, Blakely R, Crawley J, Crosbie J, Orr BO, Davis G, Genestine M, DiCicco-Bloom E, Egan S, Fink KD, Asbury S, Lai J, Rilett K, Foster J, Vincent JB, Frankland PW, Georgiades S, Penagarikano O, Geschwind D, Giger RJ, Markx S, Gogos J, Golzio C, Pagani M, Gozzi A, Pacey LK, Hampson D, Huang T-N, Yen T-L, Hsueh Y-P, Iaboni A, Amar M, Iaokoucheva L, Jones JK, Kelley EA, Kieffer B, Bae M, Jung H, Kim H, Park H, Roh JD, Kim E, Konopka G, Laliberté C, Lefebvre J, Eagleson K, Levitt P, Martins-Bach AB, Cunningham TJ, Fisher E, Miller KL, Mills AA, Muotri AR, Nicolson R, Noakes LS, Nieman BJ, Canales C, Nord AS, Nutter LMJ, Tam E, Osborne LR, Clipperton-Allen A, Page D, Babineau B, Moon A, Palmer T, Yan K, Picketts DJ, Xia Q, Powell CM, Raznahan A, Robins DM, Rumbaugh G, Sengar AS, Salter MW, Schachar R, D’Abate L, Bradley CA, Scherer SW, Copping NA, Pektova SP, Silverman J, Singh K, Kim N-S, Yoon K-J, Ming G-L, Song H, Spring S, Nakatani J, Nakai N, Nomura J, Takumi T, Tsai P, Bruce M, Jones K, Van de Water J, van Eede MC, Kerr TM, Muller C, VanderWeele JV, Vandewouw M, Weksberg R, Wevrick R, Belinson H, Wynshaw-Boris A, Zarbalis K, Trost B, Taylor M, Mars RB, Chakravarty MM, Kushki A, Anagnostou E, Lerch JP. 2025 Mar 12; bioRxiv, DOI:10.1101/2025.03.04.641443
    • Presentation
      Characterization of Immune Cells and Molecules that Promote and Suppress CNS Axon Regeneration
      Giger, Ph.D. RJ. 2025 Jul 17;
    • Journal Article
      Diverse and Location-Specific Roles of PlexinA2, PlexinA4, and NCAM in Developing Hippocampal Mossy Fibers
      Zhao X-F, Kohen R, Van Battum EY, Zeng Y, Zhang X, Johnson CN, Wang K, Lim BC, Oses-Prieto JA, Rasband JM, Burlingame AL, Pasterkamp RJ, Rasband MN, Giger RJ. bioRxiv, 2025 May 16; 2024.12.15.628586 - 2024.12.15.628586. DOI:10.1101/2024.12.15.628586
    Featured News & Stories
    Department News
    Congratulations to Roman Giger being named a AAAS Fellow!
    Roman Giger, Ph.D., is named as a 2024 American Association for the Advancement of Science (AAAS).
    Department News
    April 25, 2024 New Publication from the Giger Lab!
    "Structure and function of Semaphorin-5A glycosaminoglycan interactions," has been published in Nature Communications.