Lena Marie Napolitano, MD, FACS, FCCP, MCCM
Joyce and Don Massey Family Foundation Professor
Professor of Surgery
[email protected]

Available to mentor

Lena Marie Napolitano, MD, FACS, FCCP, MCCM
Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • Qualifications
    • Fellow in Surgical Critical Care and Trauma
      University of North Carolina at Chapel Hill, Chapel Hill, 1991
    • Chief Resident in General Surgery
      George Washington University Hospital, Washington D.C., 1990
    • General Surgery Resident
      George Washington University Hospital, Washington D.C., 1989
    • MD
      G, e, 1984
    Center Memberships
    • Center Member
      Center for Integrative Research in Critical Care
    Research Overview

    1. Anemia and blood transfusion in trauma and critical care; Hepcidin regulation of anemia
    2. Optimal Surgical Critical care outcomes. Gender differences in outcome after trauma.
    3. Clinical / biologic predictors of multiple organ dysfunction and failure after trauma or critical illness.
    4. Emergency general surgery, national and worldwide opportunities for excellence.
    5. The role of the gastrointestinal tract as a potentiator of organ dysfunction, sepsis and hypermetabolism in surgical patients. Altered gut permeability and gut mucosal immunity associated with trauma or surgery.

    Recent Publications See All Publications
    • Journal Article
      Early management of adult traumatic spinal cord injury in patients with polytrauma: a consensus and clinical recommendations jointly developed by the World Society of Emergency Surgery (WSES) & the European Association of Neurosurgical Societies (EANS).
      Picetti E, Demetriades AK, Catena F, Aarabi B, Abu-Zidan FM, Alves OL, Ansaloni L, Armonda RA, Badenes R, Bala M, Balogh ZJ, Barbanera A, Bertuccio A, Biffl WL, Bouzat P, Buki A, Castano-Leon AM, Cerasti D, Citerio G, Coccolini F, Coimbra R, Coniglio C, Costa F, De Iure F, Depreitere B, Fainardi E, Fehlings MJ, Gabrovsky N, Godoy DA, Gruen P, Gupta D, Hawryluk GWJ, Helbok R, Hossain I, Hutchinson PJ, Iaccarino C, Inaba K, Ivanov M, Kaprovoy S, Kirkpatrick AW, Klein S, Kolias A, Konovalov NA, Lagares A, Lippa L, Loza-Gomez A, Luoto TM, Maas AIR, Maciejczak A, Maier RV, Marklund N, Martin MJ, Melloni I, Mendoza-Lattes S, Meyfroidt G, Munari M, Napolitano LM, Okonkwo DO, Otomo Y, Papadopoulos MC, Petr O, Peul WC, Pudkrong AK, Qasim Z, Rasulo F, Reizinho C, Ringel F, Rizoli S, Rostami E, Rubiano AM, Russo E, Sarwal A, Schwab JM, Servadei F, Sharma D, Sharif S, Shiban E, Shutter L, Stahel PF, Taccone FS, Terpolilli NA, Thomé C, Toth P, Tsitsopoulos PP, Udy A, Vaccaro AR, Varon AJ, Vavilala MS, Younsi A, Zackova M, Zoerle T, Robba C. World J Emerg Surg, 2024 Jan 18; 19 (1): 4 DOI:10.1186/s13017-023-00525-4
      PMID: 38238783
    • Journal Article
      Early management of adult traumatic spinal cord injury in patients with polytrauma: a consensus and clinical recommendations jointly developed by the World Society of Emergency Surgery (WSES) & the European Association of Neurosurgical Societies (EANS).
      Picetti E, Demetriades AK, Catena F, Aarabi B, Abu-Zidan FM, Alves OL, Ansaloni L, Armonda RA, Badenes R, Bala M, Balogh ZJ, Barbanera A, Bertuccio A, Biffl WL, Bouzat P, Buki A, Castano-Leon AM, Cerasti D, Citerio G, Coccolini F, Coimbra R, Coniglio C, Costa F, De Iure F, Depreitere B, Fainardi E, Fehlings MJ, Gabrovsky N, Godoy DA, Gruen P, Gupta D, Hawryluk GWJ, Helbok R, Hossain I, Hutchinson PJ, Iaccarino C, Inaba K, Ivanov M, Kaprovoy S, Kirkpatrick AW, Klein S, Kolias A, Konovalov NA, Lagares A, Lippa L, Loza-Gomez A, Luoto TM, Maas AIR, Maciejczak A, Maier RV, Marklund N, Martin MJ, Melloni I, Mendoza-Lattes S, Meyfroidt G, Munari M, Napolitano LM, Okonkwo DO, Otomo Y, Papadopoulos MC, Petr O, Peul WC, Pudkrong AK, Qasim Z, Rasulo F, Reizinho C, Ringel F, Rizoli S, Rostami E, Rubiano AM, Russo E, Sarwal A, Schwab JM, Servadei F, Sharma D, Sharif S, Shiban E, Shutter L, Stahel PF, Taccone FS, Terpolilli NA, Thomé C, Toth P, Tsitsopoulos PP, Udy A, Vaccaro AR, Varon AJ, Vavilala MS, Younsi A, Zackova M, Zoerle T, Robba C. World J Emerg Surg, 2024 Jan 18; 19 (1): 4 DOI:10.1186/s13017-023-00525-4
      PMID: 38238783
    • Journal Article
      Improving outcomes in emergency general surgery: Construct of a collaborative quality initiative.
      Hemmila MR, Neiman PU, Hoppe BL, Gerhardinger L, Kramer KA, Jakubus JL, Mikhail JN, Yang AY, Lindsey HJ, Golden RJ, Mitchell EJ, Scott JW, Napolitano LM. J Trauma Acute Care Surg, 2024 May 1; 96 (5): 715 - 726. DOI:10.1097/TA.0000000000004248
      PMID: 38189669
    • Journal Article
      Modern mechanical ventilation strategies for the acute care surgeon: What you need to know.
      Park PK, Napolitano LM. J Trauma Acute Care Surg, 2024 Apr 1; 96 (4): 523 - 536. DOI:10.1097/TA.0000000000004194
      PMID: 38196095
    • Journal Article
      Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action.
      Worldwide Antimicrobial Resistance National/International Network Group (WARNING) Collaborators . World J Emerg Surg, 2023 Oct 16; 18 (1): 50 DOI:10.1186/s13017-023-00518-3
      PMID: 37845673
    • Journal Article
      Sigh Ventilation in Patients With Trauma: The SiVent Randomized Clinical Trial.
      Albert RK, Jurkovich GJ, Connett J, Helgeson ES, Keniston A, Voelker H, Lindberg S, Proper JL, Bochicchio G, Stein DM, Cain C, Tesoriero R, Brown CVR, Davis J, Napolitano L, Carver T, Cipolle M, Cardenas L, Minei J, Nirula R, Doucet J, Miller PR, Johnson J, Inaba K, Kao L. JAMA, 2023 Nov 28; 330 (20): 1982 - 1990. DOI:10.1001/jama.2023.21739
      PMID: 37877609
    • Journal Article
      American Association for the Surgery of Trauma/American College of Surgeons Committee on Trauma clinical protocol for management of acute respiratory distress syndrome and severe hypoxemia.
      Fawley JA, Tignanelli CJ, Werner NL, Kasotakis G, Mandell SP, Glass NE, Dries DJ, Costantini TW, Napolitano LM. J Trauma Acute Care Surg, 2023 Oct 1; 95 (4): 592 - 602. DOI:10.1097/TA.0000000000004046
      PMID: 37314843
    • Journal Article
      Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries.
      NIHR Global Health Research Unit on Global Surgery Collaborators . BJA Open, 2023 Sep; 7: 100207 DOI:10.1016/j.bjao.2023.100207
      PMID: 37655933