Marci M Lesperance, MD, MS

Marci M. Lesperance
Professor of Otolaryngology-Head and Neck Surgery
Medical School
Pediatric Otolaryngology Head and Neck Surgery
1540 E. Hospital Dr.
Ann Arbor, MI 48109
[email protected]
Available to mentor
Marci M Lesperance, MD, MS
Marci M. Lesperance
Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    Dr. Marci Lesperance is the associate chief clinical officer for Children’s Specialty and Women’s Services, University of Michigan Medical Group. She served as the division chief of Pediatric Otolaryngology at Michigan Medicine for 15 years. Her research has been funded by NIH and outside foundations. She has previously served as surgeon in chief for the Children’s and Women’s Hospital, program director for the University of Michigan’s Pediatric Otolaryngology Fellowship, and past president of the American Society of Pediatric Otolaryngology. She currently serves as the pediatric otolaryngology section editor for Cummings Otolaryngology-Head and Neck Surgery, 6th and 7th editions.

    Lesperance grew up in Northville, Michigan and attended Detroit Country Day High School. As the oldest of four children of a nurse and an engineer, she was always drawn to science and children. She received her medical degree at the University of Michigan Medical School (1988), completed her residency in otolaryngology-head and neck surgery at the University of Michigan Health System (1994) and a fellowship in pediatric otolaryngology at the Children's National Medical Center (1996).

    Through medical school at the University of Michigan, Lesperance had the opportunity to work with the renowned faculty in the otolaryngology department. She was attracted to otolaryngology by the opportunity to be an expert in the head and neck, which involves critical senses and functions such as hearing and breathing. She devotes her practice to pediatric otolaryngology for the privilege of interacting with children and their parents and help the children overcome illnesses so that they can grow and achieve their best potential.

    Qualifications

    • MS
      University of Michigan, Ann Arbor, MI, United States
      1990 - 1991
    • MD
      University of Michigan, Ann Arbor, MI, United States
      1984 - 1988
    • BS
      University of Michigan, Ann Arbor, MI, United States
      1982 - 1986

    Center Memberships

    • Center Member
      Kresge Hearing Research Institute

    Research Overview

    Dr. Marci Lesperance's research interests include hereditary hearing loss, molecular genetics of hearing loss and genetic testing.

    Recent Publications

    See All Publications
    • Journal Article
      Gene Therapy for Infants and Children With Otoferlin-Related Auditory Neuropathy Spectrum Disorder
      Lesperance MM, Devare J, McCreery RW, Cushing S, Hirose K. Ear and Hearing, 2026 Jan 1; DOI:10.1097/AUD.0000000000001773
    • Chapter
      Management of Pediatric Dysphagia, Laryngopharyngeal and Gastroesophageal Reflux Disease, and Eosinophilic Esophagitis
      Chun R, Singer A, Arvedson J. 2025 Nov 12; Cummings Otolaryngology Head and Neck Surgery,
    • Presentation
      Clinical Challenges and Opportunities for Implementing Gene Therapy for Hearing Loss
      Lesperance M, Devare J. 2025 Feb 25;
    • Chapter
      Anesthesia in Pediatric Otolaryngology
      Holman A, Eliott A, Samba S, Puglia M. 2025 Cummings Otolaryngology: Head & Neck Surgery,
    • Chapter
      Anesthesia in Pediatric Otolaryngology
      Holman A, Elliott A, Samba S, Puglia M. 2025 Dec 4; Cummings Otolaryngology: Head and Neck Surgery,
    • Proceeding / Abstract / Poster
      Hear here: community-based care for an inherited sensorineural hearing loss in the Swiss Amish of Branch County, Michigan
      Sunde KE, Pritchard AB, Lesperance M. 2023 Aug 25;
    • Chapter
      Anesthesia in Pediatric Otolaryngology
      Puglia M, Holman A, Elliott A, Gruffi C. 2022 Cummings Pediatric Otolaryngology,
    • Book
      Cummings Pediatric Otolaryngology
      Lesperance MM. 2021 Jan 1; 1 - 577. DOI:10.1016/B978-0-323-69618-0.01001-5