Noelle Carlozzi, PhD

Dr. Noelle E. Carlozzi is a Professor with Tenure in the Departments of Physical Medicine & Rehabilitation and Surgery at the University of Michigan, Michigan Medicine, and a Research Professor in the Survey Research Center at the Institute for Social Research. She is also Director of the Center for Clinical Outcomes Development and Application (CODA) at the University of Michigan. Dr. Carlozzi has a broad background in clinical psychology with specialized training in neuropsychology. She is an internationally recognized expert in patient-reported outcome measurement, care partner-reported outcome measurement, psychometrics, neuropsychological assessment, qualitative and mixed-methods research, and the development and validation of clinical outcome assessment tools. Much of her work focuses on developing and applying measures that capture the lived experiences, symptoms, functioning, health-related quality of life, and unmet needs of patients, care partners, and families affected by chronic, neurological, and disabling health conditions. Her research uses rigorous state-of-the-art measurement methods, including qualitative concept elicitation, cognitive interviewing, classical test theory, item response theory, differential item functioning analyses, computer adaptive testing, and validation of patient-reported and care partner-reported outcome measures. She has led or collaborated on the development of multiple outcome measurement systems, including the HDQLIFE measurement system for individuals with Huntington disease; the TBI-CareQOL measurement system for caregivers of people with traumatic brain injury; and the REDD-CAT measurement system, which assesses health-seeking behaviors and social determinants of health among people with type 2 diabetes mellitus. Dr. Carlozzi’s research portfolio includes extensive experience on federally, foundation, industry, and patient-centered research projects. Her work spans a wide range of clinical and caregiving populations, including Huntington disease, traumatic brain injury, dementia and Alzheimer’s disease-related dementias, spinal cord injury, stroke, nephrotic syndrome and other kidney diseases, diabetes, dizziness and vestibular disorders, lipodystrophy syndromes, surgical populations, pediatric conditions, and care partners across these groups. A major focus of her current work is improving measurement and intervention science for care partners and families. She currently leads NIH-funded studies focused on developing new measures to characterize informal dementia caregiver networks, including nontraditional caregivers, and new measures of financial stress, financial strain, asset depletion, and financial toxicity among families affected by dementia. This work aims to better capture caregiving experiences that are often overlooked in research and clinical care, particularly among extended family members, friends, neighbors, fictive kin, and other informal care partners. Dr. Carlozzi also has substantial expertise in mobile health, intensive longitudinal assessment, real-time patient-reported outcomes, wearable-based data collection, and just-in-time adaptive interventions. Her recent work uses mHealth applications, passive sensing, and repeated real-world assessments to understand daily variation in symptoms, functioning, and health-related quality of life, and to deliver personalized self-management support to care partners when and where it is most needed. In addition to her research, Dr. Carlozzi provides expert consultation to academic investigators, clinicians, health systems, federal partners, and industry collaborators interested in patient-reported outcomes, clinical outcome assessments, computer adaptive testing, NIH Toolbox measures, PROMIS, Neuro-QoL, qualitative methods, psychometrics, and measurement selection for clinical trials and clinical care.

patient-reported outcomes; neuropsychological assessment; mhealth just-in-time adaptive behavioral interventions; caregivers; traumatic brain injury; Huntington disease; dementia; psychometrics