Katharine Barald, PhD
Professor Emeritus/a
[email protected]

Available to mentor
Katharine Barald, PhD
Professor Emeritus/a
  • Research Overview
  • Recent Publications
    • Research Overview

    Birds and fish can regenerate their hearing organs and inner ear neurons, but mammals can't. What crucial molecular and cellular differences in the way the inner ear forms and regenerates are responsible for these differences? What role does the immune system play in inner ear development and its possible repair? Can these findings be used to enhance cochlear implant function?

    Recent Publications See All Publications
    • Journal Article
      Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2).
      Shen Y-C, Arellano-Garcia C, Menjivar RE, Jewett EM, Dohle W, Karchugina S, Chernoff J, Potter BVL, Barald KF. BMC Pharmacol Toxicol, 2019 Nov 15; 20 (1): 67 DOI:10.1186/s40360-019-0369-8
      PMID: 31730023
    • Journal Article
      Chemokines and cytokines on the neuroimmunoaxis: Inner ear neurotrophic cytokines in development and disease. Prospects for repair?
      Barald KF, Shen Y-C, Bianchi LM. Exp Neurol, 2018 Mar; 301 (Pt B): 92 - 99. DOI:10.1016/j.expneurol.2017.10.009
      PMID: 29080793
    • Journal Article
      The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development.
      Weber LJ, Marcy HK, Shen Y-C, Tomkovich SE, Brooks KM, Hilk KE, Barald KF. Exp Neurol, 2018 Mar; 301 (Pt B): 100 - 109. DOI:10.1016/j.expneurol.2017.09.009
      PMID: 28928022
    • Journal Article
      A drop array culture for patterning adherent mouse embryonic stem cell-derived neurospheres.
      Dixon AR, Ramirez Y, Haengel K, Barald KF. J Tissue Eng Regen Med, 2018 Jan; 12 (1): e379 - e383. DOI:10.1002/term.2389
      PMID: 27943657
    • Journal Article
      Concomitant differentiation of a population of mouse embryonic stem cells into neuron-like cells and schwann cell-like cells in a slow-flow microfluidic device.
      Ramamurthy P, White JB, Yull Park J, Hume RI, Ebisu F, Mendez F, Takayama S, Barald KF. Dev Dyn, 2017 Jan; 246 (1): 7 - 27. DOI:10.1002/dvdy.24466
      PMID: 27761977
    • Journal Article
      Targeted NF1 cancer therapeutics with multiple modes of action: small molecule hormone-like agents resembling the natural anticancer metabolite, 2-methoxyoestradiol.
      Shen Y-C, Upadhyayula R, Cevallos S, Messick RJ, Hsia T, Leese MP, Jewett DM, Ferrer-Torres D, Roth TM, Dohle W, Potter BVL, Barald KF. Br J Cancer, 2015 Oct 20; 113 (8): 1158 - 1167. DOI:10.1038/bjc.2015.345
      PMID: 26461061
    • Journal Article
      Recent developments in multiplexing techniques for immunohistochemistry.
      Dixon AR, Bathany C, Tsuei M, White J, Barald KF, Takayama S. Expert Rev Mol Diagn, 2015 15 (9): 1171 - 1186. DOI:10.1586/14737159.2015.1069182
      PMID: 26289603
    • Proceeding / Abstract / Poster
      Neuronal differentiation of mouse embryonic stem cells using microfluidic spatial confinement of cell parts and soluble factors
      Dixon AR, Anthony T, Ramirez Y, Barald KF. Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC, 2014 Dec 2; 2014-December: DOI:10.1109/NEBEC.2014.6972775