After completing my medical training and residency in Pediatrics at Washington University in Saint Louis, I began my subspecialty training in Neonatology at the University of Michigan. During my fellowship training I worked as a postdoctoral fellow in the laboratory of David Ginsburg where I learned to use modern genetic techniques to investigate disorders of bleeding and thrombosis. I have established in independent bench research program focused on thrombosis and hemostasis and have established national and international collborations. As an active attending Neonatologist, my clinical work focuses on the care of newborns with severe illness related to prematurity, transitional disorders, congenital anomalies or overwhelming infection. I also provide antenatal consultation to parents with complicated pregnancies. I work in a multidisciplinary level 4 NICU where I lead teams of neonatology fellows, pediatric residents and advance practice nurses and physician assistants. I have been directing recruitment of new faculty to our Division of Neonatal-Perinatal Medicine for three years. I have specific clinical interests in the area of transfusion, anticoagulation and ECMO and have helped to develop clinical practice guidlines in our NICU related to these areas.

My laboratory investigates the genetic determinants of complex phenotypes that surround the maintenance of hemostasis and the avoidance of hemorrhage or excessive thrombosis. We have developed expertise in computational genetics (genome-wide association studies, rare variant association studies, mendelian randomization) and bench based genetic screens (phage display, deep mutational scanning, lentivirus delivered CRISPR targeting and proximity labeling proteomics). I train undergraduates, PhD and post-doctoral fellows in basic cell and molecular biology techniques to answer questions regarding the role of human genetic variation in thrombosis and hemostasis. My research work is primarily funded by the NIH-NHLBI. I serve on ad hoc NIH F30/F31/F32 and R01 study sections and I am an active member of the American Society of Hematology where I serve on ASH Scholar study sections and until 2023 on the scientific subcommittee on Epigenetics and Genomics. I have established institutional, national and international collaborations and present our work at national and international meetings. I currently serve as an associate editor for the Journal of Thrombosis and Haemostasis focusing on manuscripts using genomic tools or pediatric populations. I serve on the variant curation expert panel for von Willebrand disease as a part of ClinGen.