Robert H Bartlett Collegiate Professor of the Life Sciences
Research Associate Professor
Life Sciences Institute
Associate Professor of Internal Medicine
Associate Professor of Cell and Developmental Biology
[email protected]
Available to mentor
Cheng-yu Lee
Research Associate Professor
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Center MemberCenter for Cell Plasticity and Organ Design
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Center MemberRogel Cancer Center
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Komori H, Rastogi G, Bugay JP, Luo H, Lin S, Angers S, Smibert CA, Lipshitz HD, Lee C-Y. bioRxiv, 2024 Apr 30;Journal ArticlePost-transcriptional regulatory pre-complex assembly drives timely cell-state transitions during differentiation.
DOI:10.1101/2024.04.29.591706 PMID: 38746105 -
Rajan A, Anhezini L, Rives-Quinto N, Chhabra JY, Neville MC, Larson ED, Goodwin SF, Harrison MM, Lee C-Y. Elife, 2023 Jun 14; 12:Journal ArticleLow-level repressive histone marks fine-tune gene transcription in neural stem cells.
DOI:10.7554/eLife.86127 PMID: 37314324 -
Rajan A, Anhezini L, Rives-Quinto N, Neville MC, Larson ED, Goodwin SF, Harrison MM, Lee C-Y. bioRxiv,PreprintLow-level repressive histone marks fine-tune stemness gene transcription in neural stem cells
DOI:10.1101/2022.11.18.517130 -
Larson ED, Komori H, Fitzpatrick ZA, Krabbenhoft SD, Lee C-Y, Harrison M. G3 (Bethesda), 2022 Aug 25; 12 (9):Journal ArticlePremature translation of the Drosophila zygotic genome activator Zelda is not sufficient to precociously activate gene expression.
DOI:10.1093/g3journal/jkac159 PMID: 35876878 -
Larson ED, Komori H, Fitzpatrick ZA, Krabbenhoft SD, Lee C-Y, Harrison M. bioRxiv,PreprintPremature translation of the zygotic genome activator Zelda is not sufficient to precociously activate gene expression
DOI:10.1101/2022.03.22.485419 -
Rajan A, Ostgaard CM, Lee C-Y. Int J Mol Sci, 2021 Nov 28; 22 (23):Journal ArticleRegulation of Neural Stem Cell Competency and Commitment during Indirect Neurogenesis.
DOI:10.3390/ijms222312871 PMID: 34884676 -
Larson ED, Komori H, Gibson TJ, Ostgaard CM, Hamm DC, Schnell JM, Lee C-Y, Harrison MM. Nat Commun, 2021 Dec 9; 12 (1): 7153Journal ArticleCell-type-specific chromatin occupancy by the pioneer factor Zelda drives key developmental transitions in Drosophila.
DOI:10.1038/s41467-021-27506-y PMID: 34887421 -
2021 Jul 1;PresentationSequential activation of transcriptional repressors safeguards indirect neurogenesis by decommissioning the enhancer of stem cell functionality genes during progenitor commitment