Corydon Ford Collegiate Professor
Professor of Cell and Developmental Biology
[email protected]
Available to mentor
Billy Tsai
Professor
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Xu X, Bell TW, Le T, Zhao I, Walker E, Wang Y, Xu N, Soleimanpour SA, Russ HA, Qi L, Tsai B, Liu M, Arvan P. Diabetes, 2024 Dec 1; 73 (12): 2034 - 2044.Journal ArticleRole of Sec61α2 Translocon in Insulin Biosynthesis.
DOI:10.2337/db24-0115 PMID: 39325584 -
Choi J, Speckhart K, Tsai B, DiMaio D. mBio, 2024 Nov 13; 15 (11): e0281124Journal ArticleRab6a enables BICD2/dynein-mediated trafficking of human papillomavirus from the trans-Golgi network during virus entry.
DOI:10.1128/mbio.02811-24 PMID: 39431827 -
Knupp J, Chen Y-J, Wang E, Arvan P, Tsai B. Cell Rep, 2024 Aug 27; 43 (8): 114619Journal ArticleSigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy.
DOI:10.1016/j.celrep.2024.114619 PMID: 39128005 -
Speckhart K, Choi J, DiMaio D, Tsai B. PLoS Pathog, 2024 Jun; 20 (6): e1012289Journal ArticleThe BICD2 dynein cargo adaptor binds to the HPV16 L2 capsid protein and promotes HPV infection.
DOI:10.1371/journal.ppat.1012289 PMID: 38829892 -
Chen Y-J, Knupp J, Wang E, Arvan P, Tsai B. Autophagy, 2024 Dec; 20 (12): 2843 - 2845.Journal ArticleSIGMAR1/Sigma-1 receptor: a key regulator in stabilizing and translating LC3B mRNA for autophagosome formation.
DOI:10.1080/15548627.2024.2413313 PMID: 39369298 -
Knupp J, Pletan ML, Arvan P, Tsai B. FEBS J, 2023 Dec; 290 (24): 5656 - 5673.Journal ArticleAutophagy of the ER: the secretome finds the lysosome.
DOI:10.1111/febs.16986 PMID: 37920925 -
Pletan M, Liu X, Cha G, Chen Y-J, Knupp J, Tsai B. J Virol, 2023 Aug 31; 97 (8): e0075623Journal ArticleThe atlastin ER morphogenic proteins promote formation of a membrane penetration site during non-enveloped virus entry.
DOI:10.1128/jvi.00756-23 PMID: 37578227 -
Williams JM, Chen Y-J, Cho WJ, Tai AW, Tsai B. J Cell Biol, 2023 Jul 3; 222 (7):Journal ArticleReticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication.
DOI:10.1083/jcb.202203060 PMID: 37093123
Department News
The W.M. Keck Foundation has awarded $1.3M to Assistant Professor Ryan Baldridge, Biological Chemistry, and Corydon Ford Collegiate Professor Billy Tsai, CDB, to develop a next-generation protein degradation technology to revolutionize antiviral treatments for endoplasmic reticulum (ER) dysfunction.
Department News
U-M Medical School researchers Ryan Baldridge, PhD, and Billy Tsai, PhD, are recipients of a $1.3 million grant from the W. M. Keck Foundation.
Department News
New publication by Jeffrey Knupp and Madison Pletan (Tsai Lab)