Huira Chong Kopera, PhD
Associate Research Scientist
[email protected]

Available to mentor

Huira Chong Kopera, PhD
Associate Research Scientist
  • Qualifications
  • Recent Publications
  • Qualifications
    • Postdoctoral Research Fellow
      University of Michigan, Human Genetics, 2012
    Recent Publications See All Publications
    • Journal Article
      Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development.
      Chung C, Yang X, Bae T, Vong KI, Mittal S, Donkels C, Westley Phillips H, Li Z, Marsh APL, Breuss MW, Ball LL, Garcia CAB, George RD, Gu J, Xu M, Barrows C, James KN, Stanley V, Nidhiry AS, Khoury S, Howe G, Riley E, Xu X, Copeland B, Wang Y, Kim SH, Kang H-C, Schulze-Bonhage A, Haas CA, Urbach H, Prinz M, Limbrick DD, Gurnett CA, Smyth MD, Sattar S, Nespeca M, Gonda DD, Imai K, Takahashi Y, Chen H-H, Tsai J-W, Conti V, Guerrini R, Devinsky O, Silva WA, Machado HR, Mathern GW, Abyzov A, Baldassari S, Baulac S, Focal Cortical Dysplasia Neurogenetics Consortium , Brain Somatic Mosaicism Network , Gleeson JG. Nat Genet, 2023 Feb; 55 (2): 209 - 220. DOI:10.1038/s41588-022-01276-9
      PMID: 36635388
    • Journal Article
      Control-independent mosaic single nucleotide variant detection with DeepMosaic.
      Yang X, Xu X, Breuss MW, Antaki D, Ball LL, Chung C, Shen J, Li C, George RD, Wang Y, Bae T, Cheng Y, Abyzov A, Wei L, Alexandrov LB, Sebat JL, NIMH Brain Somatic Mosaicism Network , Gleeson JG. Nat Biotechnol, 2023 Jun; 41 (6): 870 - 877. DOI:10.1038/s41587-022-01559-w
      PMID: 36593400
    • Journal Article
      Somatic mosaicism reveals clonal distributions of neocortical development.
      Breuss MW, Yang X, Schlachetzki JCM, Antaki D, Lana AJ, Xu X, Chung C, Chai G, Stanley V, Song Q, Newmeyer TF, Nguyen A, O'Brien S, Hoeksema MA, Cao B, Nott A, McEvoy-Venneri J, Pasillas MP, Barton ST, Copeland BR, Nahas S, Van Der Kraan L, Ding Y, NIMH Brain Somatic Mosaicism Network , Glass CK, Gleeson JG. Nature, 2022 Apr; 604 (7907): 689 - 696. DOI:10.1038/s41586-022-04602-7
      PMID: 35444276
    • Journal Article
      Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability.
      Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, Roberts RC, Huttner A, Kleinman JE, Hyde TM, Straub RE, Walsh CA, Brain Somatic Mosaicism Network§ , Urban AE, Leckman JF, Weinberger DR, Vaccarino FM, Abyzov A. Science, 2022 Jul 29; 377 (6605): 511 - 517. DOI:10.1126/science.abm6222
      PMID: 35901164
    • Journal Article
      A neurodegeneration gene, WDR45, links impaired ferritinophagy to iron accumulation.
      Aring L, Choi E-K, Kopera H, Lanigan T, Iwase S, Klionsky DJ, Seo YA. J Neurochem, 2022 Feb; 160 (3): 356 - 375. DOI:10.1111/jnc.15548
      PMID: 34837396
    • Journal Article
      Comprehensive identification of somatic nucleotide variants in human brain tissue.
      Wang Y, Bae T, Thorpe J, Sherman MA, Jones AG, Cho S, Daily K, Dou Y, Ganz J, Galor A, Lobon I, Pattni R, Rosenbluh C, Tomasi S, Tomasini L, Yang X, Zhou B, Akbarian S, Ball LL, Bizzotto S, Emery SB, Doan R, Fasching L, Jang Y, Juan D, Lizano E, Luquette LJ, Moldovan JB, Narurkar R, Oetjens MT, Rodin RE, Sekar S, Shin JH, Soriano E, Straub RE, Zhou W, Chess A, Gleeson JG, Marquès-Bonet T, Park PJ, Peters MA, Pevsner J, Walsh CA, Weinberger DR, Brain Somatic Mosaicism Network , Vaccarino FM, Moran JV, Urban AE, Kidd JM, Mills RE, Abyzov A. Genome Biol, 2021 Mar 29; 22 (1): 92 DOI:10.1186/s13059-021-02285-3
      PMID: 33781308
    • Journal Article
      Landmarks of human embryonic development inscribed in somatic mutations.
      Bizzotto S, Dou Y, Ganz J, Doan RN, Kwon M, Bohrson CL, Kim SN, Bae T, Abyzov A, NIMH Brain Somatic Mosaicism Network , Park PJ, Walsh CA. Science, 2021 Mar 19; 371 (6535): 1249 - 1253. DOI:10.1126/science.abe1544
      PMID: 33737485
    • Journal Article
      Principles of Genetic Engineering.
      Lanigan TM, Kopera HC, Saunders TL. Genes (Basel), 2020 Mar 10; 11 (3): DOI:10.3390/genes11030291
      PMID: 32164255
    Featured News & Stories
    Department News
    Highlighted Publications - July 2024
    Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
    Department News
    Highlighted Publications - June 2024
    Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.