Myron Levine Distinguished University Professor of Human Genetics
Professor of Human Genetics
Professor of Neurology
Medical School
[email protected]
Available to mentor
Miriam H Meisler
Professor
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Center MemberCenter for Cell Plasticity and Organ Design
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Doctrove Q, Park Y, Calame DG, Kitzman J, Lenk GM, Meisler MH. Mammalian Genome, 2025 Mar 1; 36 (1): 83 - 92.Journal ArticleProtein family FAM241 in human and mouse
DOI:10.1007/s00335-024-10096-7 PMID: 39715844 -
Yu W, Hill SF, Huang Y, Zhu L, Demetriou Y, Ziobro J, Reger F, Jia X, Mattis J, Meisler MH. Annals of Neurology, 2024 Nov 1; 96 (5): 958 - 969.Journal ArticleAllele-Specific Editing of a Dominant SCN8A Epilepsy Variant Protects against Seizures and Lethality in a Murine Model
DOI:10.1002/ana.27053 PMID: 39158034 -
Yu W, Hill S, Zhu L, Demetriou Y, Reger F, Mattis J, Meisler M. Neurobiology of Disease, 2024 Jul 8; 199:Journal ArticleDentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy
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Meyer-Schuman R, Cale AR, Pierluissi JA, Jonatzke KE, Park YN, Lenk GM, Oprescu SN, Grachtchouk MA, Dlugosz AA, Beg AA, Meisler MH, Antonellis A. Human Genetics and Genomics Advances, 2024 Jul 18; 5 (3):Journal ArticleA model organism pipeline provides insight into the clinical heterogeneity of TARS1 loss-of-function variants
DOI:10.1016/j.xhgg.2024.100324 PMID: 38956874 -
Accogli A, Park YN, Lenk GM, Severino M, Scala M, Denecke J, Hempel M, Lessel D, Kortüm F, Salpietro V, de Marco P, Guerrisi S, Torella A, Nigro V, Srour M, Turro E, Labarque V, Freson K, Piatelli G, Capra V, Kitzman JO, Meisler MH. Genetics in Medicine, 2024 May 1; 26 (5):Journal ArticleBiallelic loss-of-function variants of SLC12A9 cause lysosome dysfunction and a syndromic neurodevelopmental disorder
DOI:10.1016/j.gim.2024.101097 PMID: 38334070 -
Yamakawa K, Meisler MH, Isom LL. 2024 Jul 29; Jasper's Basic Mechanisms of the Epilepsies, 881 - 920.ChapterSodium Channelopathies in Human and Animal Models of Epilepsy and Neurodevelopmental Disorders
DOI:10.1093/med/9780197549469.003.0044 -
Hill* SF, Yu* W, Ziobro J, Chalasani S, Reger F, Meisler MH. Annals of Neurology, 2024 Apr 1; 95 (4): 754 - 759.Journal ArticleLong-Term Downregulation of the Sodium Channel Gene Scn8a Is Therapeutic in Mouse Models of SCN8A Epilepsy
DOI:10.1002/ana.26861 PMID: 38113311 -
Meyer-Schuman R, Cale AR, Pierluissi JA, Jonatzke KE, Park YN, Lenk GM, Oprescu SN, Grachtchouk MA, Dlugosz AA, Beg AA, Meisler MH, Antonellis A. 2024 Mar 27;PreprintPredictive modeling provides insight into the clinical heterogeneity associated with TARS1 loss-of-function mutations.
DOI:10.1101/2024.03.25.586600 PMID: 38585737
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
