1500 East Medical Center Drive, UH B2C490 SPC 5010
Ann Arbor, MI 48109
Available to mentor
As Co-Chair of the Cancer Center Neuro-Oncology Clinical Research Team and Principal Investigator of multiple clinical trials, Dr. Kim is a leader in brain tumor clinical research and involved with efforts institutionally, regionally and nationally. Her primary focus is on the use of advanced imaging modalities as a biomarker to understand the biologic basis of tumor response and treatment resistance to radiation therapy, in order to individually adapt radiation treatment and improve outcome in patients with malignant gliomas. She is also interested in the evaluation of advanced imaging techniques to predict long-term toxicity and response in patients with low grade gliomas and brain metastases. Dr. Kim is principal investigator of several ongoing clinical trials evaluating the use of a newly developed advanced MR imaging technique for the intensification of radiation treatment in patients with newly diagnosed glioblastoma, and the evaluation of a novel radiosensitizer (RRx-001) in combination with radiotherapy in patients with brain metastases.
Personal page on department website Department of Radiation Oncology
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ResidentThe University of Texas MD Anderson Cancer Center, Radiation Oncology, 2013
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InternMetroHealth Medical Center, Cleveland, 2009
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MDCase Western Reserve University School of Medicine, Cleveland, 2008
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BACase Western Reserve University, 10900 Euclid Avenue, 2004
Prediction of treatment response and adaptive individualization of radiation treatment using advanced imaging modalities in malignant gliomas
Evaluation of novel, targeted radiosensitizers in patients with brain metastases
Clinical trials for brain metastases and adult gliomas
Adult central nervous system tumors of the brain and spine
Stereotactic radiosurgery
Stereotactic body radiation therapy
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Kim IA, Winter KA, Sperduto PW, De Los Santos JF, Peereboom DM, Ogunleye T, Boulter D, Fritz JM, Cho KH, Shin KH, Zoberi I, Choi S, Palmer JD, Liem B, Kim YB, Anderson BM, Thakrar AW, Muanza TM, Kim MM, Choi DH, Mehta MP, White JR. Int J Radiat Oncol Biol Phys, 2024 Apr 1; 118 (5): 1391 - 1401.Journal ArticleConcurrent Lapatinib With Brain Radiation Therapy in Patients With HER2+ Breast Cancer With Brain Metastases: NRG Oncology-KROG/RTOG 1119 Phase 2 Randomized Trial.
DOI:10.1016/j.ijrobp.2023.07.019 PMID: 37506981 -
Breen WG, Aryal MP, Cao Y, Kim MM. Neuro Oncol, 2024 Mar 4; 26 (12 Suppl 2): S17 - S25.Journal ArticleIntegrating multi-modal imaging in radiation treatments for glioblastoma.
DOI:10.1093/neuonc/noad187 PMID: 38437666 -
Redmond KJ, Hattangadi-Gluth J, Pollum EL, Trifiletti DM, Kim MM, Milano M. Int J Radiat Oncol Biol Phys, 2024 Feb 1; 118 (2): 313 - 317.Journal ArticleNavigating the Spinal Frontier: Recent Data on Stereotactic Body Radiation Therapy for Spine Metastases.
DOI:10.1016/j.ijrobp.2023.11.015 PMID: 38220248 -
Karschnia P, Smits M, Reifenberger G, Le Rhun E, Ellingson BM, Galldiks N, Kim MM, Huse JT, Schnell O, Harter PN, Mohme M, Expert Rater Panel , von Baumgarten L, Albert NL, Huang RY, Mehta MP, van den Bent M, Weller M, Vogelbaum MA, Chang SM, Berger MS, Tonn J-C. Lancet Oncol, 2023 Nov; 24 (11): e438 - e450.Journal ArticleA framework for standardised tissue sampling and processing during resection of diffuse intracranial glioma: joint recommendations from four RANO groups.
DOI:10.1016/S1470-2045(23)00453-9 PMID: 37922934 -
Scott AJ, Correa LO, Edwards DM, Sun Y, Ravikumar V, Andren AC, Zhang L, Srinivasan S, Jairath N, Verbal K, Muraszko K, Sagher O, Carty SA, Hervey-Jumper S, Orringer D, Kim MM, Junck L, Umemura Y, Leung D, Venneti S, Camelo-Piragua S, Lawrence TS, Ippolito JE, Al-Holou WN, Chinnaiyan P, Heth J, Rao A, Lyssiotis CA, Wahl DR. Antioxid Redox Signal, 2023 Nov; 39 (13-15): 942 - 956.Journal ArticleMetabolomic Profiles of Human Glioma Inform Patient Survival.
DOI:10.1089/ars.2022.0085 PMID: 36852494 -
Trifiletti DM, Milano MT, Redmond KJ, Pollom EL, Hattangadi-Gluth JA, Kim MM. Int J Radiat Oncol Biol Phys, 2023 Oct 1; 117 (2): 293 - 296.Journal ArticleTreatment Planning Expansions in Glioblastoma: How Less Can Be More.
DOI:10.1016/j.ijrobp.2023.03.062 PMID: 37652602 -
Umemura Y, Orringer D, Junck L, Varela ML, West MEJ, Faisal SM, Comba A, Heth J, Sagher O, Leung D, Mammoser A, Hervey-Jumper S, Zamler D, Yadav VN, Dunn P, Al-Holou W, Hollon T, Kim MM, Wahl DR, Camelo-Piragua S, Lieberman AP, Venneti S, McKeever P, Lawrence T, Kurokawa R, Sagher K, Altshuler D, Zhao L, Muraszko K, Castro MG, Lowenstein PR. Lancet Oncol, 2023 Sep; 24 (9): 1042 - 1052.Journal ArticleCombined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
DOI:10.1016/S1470-2045(23)00347-9 PMID: 37657463 -
Venneti S, Kawakibi AR, Ji S, Waszak SM, Sweha SR, Mota M, Pun M, Deogharkar A, Chung C, Tarapore RS, Ramage S, Chi A, Wen PY, Arrillaga-Romany I, Batchelor TT, Butowski NA, Sumrall A, Shonka N, Harrison RA, de Groot J, Mehta M, Hall MD, Daghistani D, Cloughesy TF, Ellingson BM, Beccaria K, Varlet P, Kim MM, Umemura Y, Garton H, Franson A, Schwartz J, Jain R, Kachman M, Baum H, Burant CF, Mottl SL, Cartaxo RT, John V, Messinger D, Qin T, Peterson E, Sajjakulnukit P, Ravi K, Waugh A, Walling D, Ding Y, Xia Z, Schwendeman A, Hawes D, Yang F, Judkins AR, Wahl D, Lyssiotis CA, de la Nava D, Alonso MM, Eze A, Spitzer J, Schmidt SV, Duchatel RJ, Dun MD, Cain JE, Jiang L, Stopka SA, Baquer G, Regan MS, Filbin MG, Agar NYR, Zhao L, Kumar-Sinha C, Mody R, Chinnaiyan A, Kurokawa R, Pratt D, Yadav VN, Grill J, Kline C, Mueller S, Resnick A, Nazarian J, Allen JE, Odia Y, Gardner SL, Koschmann C. Cancer Discov, 2023 Nov 1; 13 (11): 2370 - 2393.Journal ArticleClinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
DOI:10.1158/2159-8290.CD-23-0131 PMID: 37584601
