Daniel R. Goldstein obtained his medical degree from St. George’s, University of London, UK. He undertook a medical residency at Johns Hopkins Bayview Medical Center in Baltimore, MD, USA and his cardiovascular disease, heart failure and transplantation training at the University of Alabama, Birmingham (UAB). At UAB he was postdoctoral fellow studying transplantation immunology. Until April 2016, his entire faculty career has been at the Yale School of Medicine, New Haven CT, USA.

On April 1, 2016, he moved to the University of Michigan to direct a basic science center on cardiovascular aging (Michigan Biology of Cardiovascular Aging, MBOCA). His research interests include how inflammation impacts organ transplantation and how aging impacts acute and chronic inflammation. He is a member of the American Society of Clinical Investigation, an Established Investigator of the American Heart Association, a Paul Beeson Scholar in Aging Research, a recipient of an Academic Leadership Award from the National Institute on Aging, National Institute of Health, and a recipient of an Outstanding Investigator R35 award from the National Heart, Lung, and Blood Institute. In January 2021, he became the Editor-in-Chief of The Journal of Heart and Lung Transplantation www.JHLTonline.org, the journal of the www.ishlt.org.

Dr. Goldstein is interested in how aging impacts innate immunity. Currently, he works in two broad areas: aging and respiratory viral infections and aging and vascular diseases.

Active research programs:

• How aging impacts inflammation resolution during lung inflammation
• How aging impacts mitochondrial quality control to impact acute and chronic inflammation
• Role of senescence in acute viral infections
• How aging impacts the vasculature to increase transplant vasculopathy
• Mechanisms by which aging impacts atherosclerosis and aortic aneurysms